Search Results - "Cockle, Sarah"
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Clinical characteristics and burden of illness among adolescent and adult patients with severe asthma by asthma control: the IDEAL study
Published in The Journal of asthma (01-04-2021)“…Severe asthma (SA) can be uncontrolled despite guideline-directed treatment. We described SA characteristics and identified factors associated with…”
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Biologic treatment eligibility for real-world patients with severe asthma: The IDEAL study
Published in The Journal of asthma (01-02-2018)“…Objectives: Severe asthma comprises several distinct phenotypes. Consequently, patients with severe asthma can be eligible for more than one biologic treatment…”
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Comparative effectiveness of mepolizumab and omalizumab in severe asthma: An indirect treatment comparison
Published in Respiratory medicine (01-02-2017)“…Abstract Background Severe asthma is a heterogeneous disease. Patients with both eosinophilic and allergic asthma phenotypes may be eligible for treatment with…”
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Multinational cohort study of mortality in patients with asthma and severe asthma
Published in Respiratory medicine (01-04-2020)“…Data on the risk of death following an asthma exacerbation are scarce. With this multinational cohort study, we assessed all-cause mortality rates, mortality…”
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Impact of exacerbations on St George's Respiratory Questionnaire score in patients with severe asthma: post hoc analyses of two clinical trials and an observational study
Published in The Journal of asthma (01-09-2020)“…Objective: To assess the effect of asthma exacerbations and mepolizumab treatment on health status of patients with severe asthma using the St George's…”
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Mepolizumab improves work productivity, activity limitation, symptoms, and rescue medication use in severe eosinophilic asthma
Published in The clinical respiratory journal (01-03-2022)“…Patients with severe eosinophilic asthma experience daily activity limitations and reduced productivity at work. Using anonymized individual patient‐level data…”
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Qualitative evaluation of the St George's Respiratory Questionnaire in patients with severe asthma
Published in Respiratory medicine (01-05-2017)“…Abstract Purpose Content validity is the extent to which a patient-reported outcome measure evaluates the concepts most relevant to a patient's condition and…”
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Evaluation of Potential Continuation Rules for Mepolizumab Treatment of Severe Eosinophilic Asthma
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-05-2018)“…Mepolizumab significantly reduces exacerbations in patients with severe eosinophilic asthma. The early identification of patients likely to receive long-term…”
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Evaluation of the psychometric properties of the St George's Respiratory Questionnaire in patients with severe asthma
Published in Respiratory medicine (01-07-2017)“…Abstract Purpose Limited data exist on the quantitative validity of the St George's Respiratory Questionnaire (SGRQ) in asthma populations. This study…”
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Comparison of laboratory- and field-based exercise tests for COPD: a systematic review
Published in International journal of chronic obstructive pulmonary disease (01-01-2015)“…Exercise tests are often used to evaluate the functional status of patients with COPD. However, to the best of our knowledge, a comprehensive systematic…”
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Comparative efficacy of combination bronchodilator therapies in COPD: a network meta-analysis
Published in International journal of chronic obstructive pulmonary disease (01-01-2015)“…Several new fixed-dose combination bronchodilators have been recently launched, and assessing their efficacy relative to each other, and with open dual…”
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Perception of oral corticosteroid side effects in patients with corticosteroid-dependent asthma
Published in Journal of allergy and clinical immunology (01-02-2017)“…Rationale Corticosteroid-dependent patients are concerned with drug-related complications associated with long term oral corticosteroid (OCS) treatment…”
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Abstract TP68: Guideline For Acute Stroke Discharge: A Tool Developed By Nebraska Mission: Lifeline Stroke Rehabilitation Taskforce
Published in Stroke (1970) (01-02-2022)“…IntroductionNebraska MissionLifeline Stroke is a 4-year initiative to increase guideline-based treatment of acute stroke across the continuum of care…”
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Incidence, risk factors and re‐exacerbation rate of severe asthma exacerbations in a multinational, multidatabase pediatric cohort study
Published in Pediatric allergy and immunology (01-07-2020)“…Background There are sparse real‐world data on severe asthma exacerbations (SAE) in children. This multinational cohort study assessed the incidence of and…”
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Quantitative Validity of the Sgrq in Patients with Severe Asthma
Published in Journal of allergy and clinical immunology (01-02-2016)“…Methods Psychometric properties of the SGRQ were tested using treatment-masked data from two clinical trials (MENSA, SIRIUS) of mepolizumab, an anti-IL5…”
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Impact of Asthma Exacerbations on Health Status in Patients with Severe Asthma
Published in Journal of allergy and clinical immunology (01-02-2016)“…The St George's Respiratory Questionnaire (SGRQ), a measure of health status in obstructive airway disease, was measured at baseline and end of treatment in a…”
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Comparative Effectiveness of Mepolizumab and Omalizumab in Severe Asthma: An Indirect Comparison
Published in Journal of allergy and clinical immunology (01-02-2016)“…Included studies were double-blind randomized controlled clinical trials (RCTs) >=12 weeks' in duration among severe asthma patients >=12 years old, with a…”
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Systematic Review of the Association Between Laboratory- and Field-Based Exercise Tests and Lung Function in Patients with Chronic Obstructive Pulmonary Disease - See more at: http://journal.copdfoundation.org/#sthash.NtJo2ItZ.dpuf
Published in Chronic obstructive pulmonary diseases (2015)Get full text
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Systematic Review of the Association Between Laboratory- and Field-Based Exercise Tests and Lung Function in Patients with Chronic Obstructive Pulmonary Disease
Published in Chronic obstructive pulmonary diseases (08-07-2015)“…Typical symptoms of chronic obstructive pulmonary disease (COPD) include breathlessness and reduced exercise capacity. Several laboratory- and field-based…”
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