Search Results - "Cockell, M."
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Reconstitution of Yeast Silent Chromatin: Multiple Contact Sites and O-AADPR Binding Load SIR Complexes onto Nucleosomes In Vitro
Published in Molecular cell (13-02-2009)“…At yeast telomeres and silent mating-type loci, chromatin assumes a higher-order structure that represses transcription by means of the histone deacetylase…”
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The molecular biology of the SIR proteins
Published in Gene (14-11-2001)“…Silent or heritably repressed genes constitute the major fraction of genetic information in higher eukaryotic cells. Budding yeast has very little…”
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A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast
Published in The EMBO journal (15-01-2001)“…In budding yeast, the silent information regulator Sir2p is a nuclear NAD‐dependent deacetylase that is essential for both telomeric and rDNA silencing. All…”
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The Carboxy Termini of Sir4 and Rap1 Affect Sir3 Localization: Evidence for a Multicomponent Complex Required for Yeast Telomeric Silencing
Published in The Journal of cell biology (01-05-1995)“…The Silent Information Regulatory proteins, Sir3 and Sir4, and the telomeric repeat-binding protein RAP1 are required for the chromatin-mediated gene…”
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Functional Differentiation of tbf1 Orthologues in Fission and Budding Yeasts
Published in Eukaryotic Cell (01-02-2009)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae
Published in Genetics (Austin) (01-03-2000)“…Silent information regulator (Sir) 2 is a limiting component of the Sir2/3/4 complex, which represses transcription at subtelomeric and HM loci. Sir2p also…”
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The nucleolus: Nucleolar space for RENT
Published in Current biology (12-08-1999)“…Recent studies indicate that the nucleolus is not just a site of ribosome biogenesis. Intriguing links have been found between nucleolar components and the…”
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Identification of a cell-specific DNA-binding activity that interacts with a transcriptional activator of genes expressed in the acinar pancreas
Published in Molecular and Cellular Biology (01-06-1989)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Binding sites for hepatocyte nuclear factor 3 beta or 3 gamma and pancreas transcription factor 1 are required for efficient expression of the gene encoding pancreatic alpha-amylase
Published in Molecular and Cellular Biology (01-04-1995)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Targeting Sir proteins to sites of action: a general mechanism for regulated repression
Published in Cold Spring Harbor Symposia on Quantitative Biology (1998)Get full text
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Location of the primary sites of micrococcal nuclease cleavage on the nucleosome core
Published in Journal of molecular biology (25-10-1983)“…The positions and relative frequencies of the primary cleavages made by micrococcal nuclease on the DNA of nucleosome core particles have been found by…”
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Nuclear compartments and gene regulation
Published in Current opinion in genetics & development (01-04-1999)“…Improvements in fluorescence microscopy have allowed us to explore the three-dimensional organization of the nucleus in ways that were impossible ten years…”
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lis-1 is required for dynein-dependent cell division processes in C. elegans embryos
Published in Journal of cell science (01-09-2004)“…We investigated the role of the evolutionarily conserved protein Lis1 in cell division processes of Caenorhabditis elegans embryos. We identified apparent null…”
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Nuclear organization and silencing: trafficking of Sir proteins
Published in Novartis Foundation symposium (1998)“…In budding yeast genes integrated near telomeres succumb to a variegated pattern of gene repression that requires the silent information regulatory proteins…”
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Sif2p interacts with the Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast
Published in Current biology (18-06-1998)“…Several regions of the Saccharomyces cerevisiae genome are subject to position-dependent transcriptional repression mediated by a multi-component…”
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Telomeres, not the end of the story
Published in BioEssays (01-05-1997)“…Transcription in organisms as diverse as yeast and mammals is subject to chromosomal position effects that result in heritable and variegated patterns of gene…”
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yeast protein encoded by PUB1 binds T-rich single stranded DNA
Published in Nucleic acids research (11-01-1994)“…We have characterized binding activities in yeast which recognise the T-rich strand of the yeast ARS consensus element and have purified two of these to…”
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Analysis of sir2p domains required for rDNA and telomeric silencing in saccharomyces cerevisiae
Published in Genetics (Austin) (01-08-2000)Get full text
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19
Teachers' pay
Published in Times (London, England : 1788) (23-09-1995)Get full text
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Insurance policy for the EEC
Published in Times (London, England : 1788) (24-12-1980)Get full text
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