Search Results - "Cock, Hannah R"

Established Status Epilepticus Treatment Trial (ESETT) by Cock, Hannah R.

“…Summary Phenytoin (PHT) has been the standard treatment for convulsive status epilepticus (SE) where initial benzodiazepines have failed for many years,…”
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Acute down-regulation of adenosine A1 receptor activity in status epilepticus by Hamil, Nicola E., Cock, Hannah R., Walker, Matthew C.

“…Summary Purpose:  Status epilepticus (SE) remains a potentially devastating condition that quickly becomes refractory to antiepileptic drug treatment and…”
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Levetiracetam: Antiepileptic Properties and Protective Effects on Mitochondrial Dysfunction in Experimental Status Epilepticus by Gibbs, Julie E., Walker, Matthew C., Cock, Hannah R.

“…Purpose: To assess the anticonvulsant activity of the novel antiepileptic drug, levetiracetam (LEV) in a model of self‐sustaining limbic status epilepticus,…”
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Drug-induced status epilepticus by Cock, Hannah R

“…Abstract Drug-induced status epilepticus (SE) is a relatively uncommon phenomenon, probably accounting for less than 5% of all SE cases, although limitations…”
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Medical management of status epilepticus: Emergency room to intensive care unit by Crawshaw, Ania A., Cock, Hannah R.

“…•Video of seizures in the emergency department can be vital for long term management.•Seizure control within 1–2 hours improves outcome in convulsive status…”
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Antiepileptic Effect of Gap‐junction Blockers in a Rat Model of Refractory Focal Cortical Epilepsy by Nilsen, Karen E., Kelso, Andrew R. C., Cock, Hannah R.

“…Purpose: Epilepsy is the most common serious neurologic disease, and current treatments are ineffective for ≤30% of patients. Gap junctions have been…”
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Characterization of the Tetanus Toxin Model of Refractory Focal Neocortical Epilepsy in the Rat by Nilsen, Karen E., Walker, Matthew C., Cock, Hannah R.

“…Purpose: To characterize in detail a model of focal neocortical epilepsy. Methods: Chronic focal epilepsy was induced by injecting 25–50 ng of tetanus toxin or…”
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Functional neurological disorders: acute presentations and management by Cock, Hannah R, Edwards, Mark J

“…Functional neurological disorders (FND) are common and associated with significant morbidity and healthcare costs. Patients with FND often present acutely,…”
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Patterns of benzodiazepine underdosing in the Established Status Epilepticus Treatment Trial by Sathe, Abhishek G., Underwood, Ellen, Coles, Lisa D., Elm, Jordan J., Silbergleit, Robert, Chamberlain, James M., Kapur, Jaideep, Cock, Hannah R., Fountain, Nathan B., Shinnar, Shlomo, Lowenstein, Daniel H., Rosenthal, Eric S., Conwit, Robin A., Bleck, Thomas P., Cloyd, James C.

“…Objective This study was undertaken to describe patterns of benzodiazepine use as first‐line treatment of status epilepticus (SE) and test the association of…”
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Time to onset of cannabidiol treatment effect and resolution of adverse events in tuberous sclerosis complex: Post hoc analysis of randomized controlled phase 3 trial GWPCARE6 by Wu, Joyce Y., Cock, Hannah R., Devinsky, Orrin, Joshi, Charuta, Miller, Ian, Roberts, Colin M., Sanchez‐Carpintero, Rocio, Checketts, Daniel, Sahebkar, Farhad

“…Objective To estimate the timing of cannabidiol (CBD) treatment effect (seizure reduction and adverse events [AEs]) onset, we conducted a post hoc analysis of…”
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Medical student perceptions of clinical neurosurgery teaching in an undergraduate medical school curriculum by Knight, James, Stroud, Lauren, Geyton, Thomas, Stead, Anthony, Cock, Hannah R.

“…Aim: The aim of this study was to evaluate undergraduate medical student perceptions as to the value of different types of neurosurgical teaching to their…”
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Corrigendum to “Medical management of status epilepticus: Emergency room to intensive care unit” [Seizure: Eur. J. Epilep. 75 (2020) 145–152] by Crawshaw, Ania A., Cock, Hannah R.

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Valproate and the Pregnancy Prevention Programme: exceptional circumstances by Watkins, Lance V, Cock, Hannah R, Angus-Leppan, Heather, Shankar, Rohit

“…In March 2018 the European Medicines Agency endorsed new measures to avoid in utero valproate exposure. Subsequently, updated valproate regulations published…”
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Underdosing of Benzodiazepines in Patients With Status Epilepticus Enrolled in Established Status Epilepticus Treatment Trial by Sathe, Abhishek G., Tillman, Holly, Coles, Lisa D., Elm, Jordan J., Silbergleit, Robert, Chamberlain, James, Kapur, Jaideep, Cock, Hannah R., Fountain, Nathan B., Shinnar, Shlomo, Lowenstein, Daniel H., Conwit, Robin A., Bleck, Thomas P., Cloyd, James C., Panagos, Peter

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Learning from an exceptional boy by Cock, Hannah R

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Screening of anxiety and quality of life in people with epilepsy by Gur-Ozmen, Selen, Leibetseder, Annette, Cock, Hannah R, Agrawal, Niruj, von Oertzen, Tim J

“…Highlights • Moderate to severe anxiety is a frequent comorbidity in epilepsy, in our cohort prevalence was 26,4%. • Depression was the only significant…”
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Implementing clinical guidelines by Mayer, Josephine, Kipps, Christopher, Cock, Hannah R

“…Clinical guidelines that support practice and improve care are essential in this era of evidence-based medicine. However, implementing this guidance often…”
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Testing blood and CSF in people with epilepsy: a practical guide by Sutton, Fiona, Barca, Diana, Komoltsev, Ilia, Craiu, Dana, Guekht, Alla, von Oertzen, Tim, Cock, Hannah R.

“…Laboratory investigations, whilst not essential to the diagnosis of seizures or of epilepsy, can be fundamental to determining the cause and guiding…”
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The association of patient weight and dose of fosphenytoin, levetiracetam, and valproic acid with treatment success in status epilepticus by Sathe, Abhishek G., Elm, Jordan J., Cloyd, James C., Chamberlain, James M., Silbergleit, Robert, Kapur, Jaideep, Cock, Hannah R., Fountain, Nathan B., Shinnar, Shlomo, Lowenstein, Daniel H., Conwit, Robin A., Bleck, Thomas P., Coles, Lisa D.

“…The Established Status Epilepticus Treatment Trial was a blinded, comparative‐effectiveness study of fosphenytoin, levetiracetam, and valproic acid in…”
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Stress and epilepsy: fact or fiction, and what can we do about it? by Galtrey, Clare M, Mula, Marco, Cock, Hannah R

“…People with epilepsy report that stress is their most common trigger for seizures and some believe it caused their epilepsy in the first place. The extensive…”
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