Search Results - "Cochran, J"
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Isotopic evidence concerning the habitat of Nautilus macromphalus in New Caledonia
Published in PloS one (26-07-2022)“…Modern nautilids ( Nautilus and Allonautilus ) have often been studied by paleontologists to better understand the anatomy and ecology of fossil relatives…”
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Targeting GLP-1 receptor trafficking to improve agonist efficacy
Published in Nature communications (23-04-2018)“…Glucagon-like peptide-1 receptor (GLP-1R) activation promotes insulin secretion from pancreatic beta cells, causes weight loss, and is an important…”
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Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
Published in Journal of cell science (01-03-2013)“…Normally post-mitotic neurons that aberrantly re-enter the cell cycle without dividing account for a substantial fraction of the neurons that die in…”
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The status of coral reef ecology research in the Red Sea
Published in Coral reefs (01-09-2013)“…The Red Sea has long been recognized as a region of high biodiversity and endemism. Despite this diversity and early history of scientific work, our…”
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Polarized X-ray scattering reveals non-crystalline orientational ordering in organic films
Published in Nature materials (15-04-2012)“…Molecular orientation critically influences the mechanical, chemical, optical and electronic properties of organic materials. So far, molecular-scale ordering…”
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Reduced PIN1 expression in neocortical and limbic brain regions in female Alzheimer’s patients correlates with cognitive and neuropathological phenotypes
Published in Neurobiology of aging (01-09-2024)“…Women have a higher incidence of Alzheimer’s disease (AD), even after adjusting for increased longevity. Thus, there is an urgent need to identify genes that…”
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High response rate to PD-1 blockade in desmoplastic melanomas
Published in Nature (London) (18-01-2018)“…Immune checkpoint blockade with anti-PD-1 or anti-PD-L1 agents produces a high response rate in patients with desmoplastic melanoma. Highly sensitive skin…”
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Nonholonomic Source Seeking With Tuning of Angular Velocity
Published in IEEE transactions on automatic control (01-04-2009)“…We consider the problem of seeking the source of a scalar signal using an autonomous vehicle modeled as the nonholonomic unicycle. The vehicle does not have…”
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Cell-Binding Assays for Determining the Affinity of Protein-Protein Interactions: Technologies and Considerations
Published in Methods in enzymology (2016)“…Determining the equilibrium-binding affinity (Kd) of two interacting proteins is essential not only for the biochemical study of protein signaling and function…”
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Immunotherapy Resistance by Inflammation-Induced Dedifferentiation
Published in Cancer discovery (01-08-2018)“…A promising arsenal of targeted and immunotherapy treatments for metastatic melanoma has emerged over the last decade. With these therapies, we now face new…”
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Exome sequencing-based copy-number variation and loss of heterozygosity detection: ExomeCNV
Published in Bioinformatics (01-10-2011)“…Motivation: The ability to detect copy-number variation (CNV) and loss of heterozygosity (LOH) from exome sequencing data extends the utility of this powerful…”
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The dendritic hypothesis for Alzheimer's disease pathophysiology
Published in Brain research bulletin (01-04-2014)“…Highlights • Dendritic neuropathology is ubiquitous in Alzheimer's Disease (AD). • Aβ causes dendritic neuropathology in AD. • Dendritic mislocalization of Tau…”
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13
APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer’s Disease
Published in The New England journal of medicine (31-10-2024)“…To the Editor: The report by Quiroz et al. (June 20 issue) 1 on the Colombian PSEN1 E280A pedigree suggests a protective effect of apolipoprotein E3…”
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Colchicine Inhibits Neutrophil Extracellular Trap Formation in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention
Published in Journal of the American Heart Association (05-01-2021)“…Background Release of neutrophil extracellular traps (NETs) after percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) is associated with…”
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Final Version of 2009 AJCC Melanoma Staging and Classification
Published in Journal of clinical oncology (20-12-2009)“…To revise the staging system for cutaneous melanoma on the basis of data from an expanded American Joint Committee on Cancer (AJCC) Melanoma Staging Database…”
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Genomic diagnosis for children with intellectual disability and/or developmental delay
Published in Genome medicine (30-05-2017)“…Developmental disabilities have diverse genetic causes that must be identified to facilitate precise diagnoses. We describe genomic data from 371 affected…”
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Monte Carlo study of particle identification at the CEPC using TPC dE / dx information
Published in The European physical journal. C, Particles and fields (01-06-2018)“…The kaon identification is crucial for the flavor physics, and also benefits the flavor and charge reconstruction of the jets. We explore the particle…”
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New Antarctic gravity anomaly grid for enhanced geodetic and geophysical studies in Antarctica
Published in Geophysical research letters (28-01-2016)“…Gravity surveying is challenging in Antarctica because of its hostile environment and inaccessibility. Nevertheless, many ground‐based, airborne, and shipborne…”
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The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity
Published in Human molecular genetics (01-12-2015)“…CD2-associated protein (CD2AP) is a leading genetic risk factor for Alzheimer's disease, but little is known about the function of CD2AP in the brain. We…”
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Response to Holstege et al
Published in American journal of human genetics (03-09-2020)Get full text
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