Search Results - "Cochran, D.L."

Inflammation and Uncoupling as Mechanisms of Periodontal Bone Loss by Graves, D.T., Li, J., Cochran, D.L.

“…Periodontal disease is characterized by both inflammation and bone loss. Advances in research in both these areas have led to a new appreciation of not only…”
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Enhanced Bone Apposition to a Chemically Modified SLA Titanium Surface by Buser, D., Broggini, N., Wieland, M., Schenk, R.K., Denzer, A.J., Cochran, D.L., Hoffmann, B., Lussi, A., Steinemann, S.G.

“…Increased surface roughness of dental implants has demonstrated greater bone apposition; however, the effect of modifying surface chemistry remains unknown. In…”
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Peri-implant Inflammation Defined by the Implant-Abutment Interface by Broggini, N., McManus, L.M., Hermann, J.S., Medina, R., Schenk, R.K., Buser, D., Cochran, D.L.

“…An implant-abutment interface at the alveolar bone crest is associated with sustained peri-implant inflammation; however, whether magnitude of inflammation is…”
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Persistent Acute Inflammation at the Implant-Abutment Interface by Broggini, N., McManus, L.M., Hermann, J.S., Medina, R.U., Oates, T.W., Schenk, R.K., Buser, D., Mellonig, J.T., Cochran, D.L.

“…The inflammatory response adjacent to implants has not been well-investigated and may influence peri-implant tissue levels. The purpose of this study was to…”
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Biomechanical evaluation of the interfacial strength of a chemically modified sandblasted and acid-etched titanium surface by Ferguson, S.J., Broggini, N., Wieland, M., de Wild, M., Rupp, F., Geis-Gerstorfer, J., Cochran, D.L., Buser, D.

“…The functional capacity of osseointegrated dental implants to bear load is largely dependent on the quality of the interface between the bone and implant…”
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In Vitro Wound Healing Responses to Enamel Matrix Derivative by Hoang, A.M., Oates, T.W., Cochran, D.L.

“…Background: Enamel matrix derivative (EMD) contains a variety of hydrophobic enamel matrix proteins and is extracted from developing embryonal enamel of…”
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Amelogenin is a Cell Adhesion Protein by Hoang, A.M., Klebe, R.J., Steffensen, B., Ryu, O.H., Simmer, J.P., Cochran, D.L.

“…Amelogenin, the major protein component of tooth enamel, is shown to be a cell adhesion protein. Since it had been shown that an amelogenin-containing…”
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Ability of Deproteinized Cancellous Bovine Bone to Induce New Bone Formation by Schwartz, Z., Weesner, T., Van Dijk, S., Cochran, D.L., Mellonig, J.T., Lohmann, C.H., Carnes, D.L., Goldstein, M., Dean, D.D., Boyan, B.D.

“…Background: Preclinical and clinical studies indicate that deproteinized cancellous bovine bone is osteoconductive and may be osteopromotive. Previous studies…”
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Porcine Fetal Enamel Matrix Derivative Enhances Bone Formation Induced by Demineralized Freeze Dried Bone Allograft In Vivo by Boyan, B.D., Weesner, T.C., Lohmann, C.H., Andreacchio, D., Carnes, D.L., Dean, D.D., Cochran, D.L., Schwartz, Z.

“…Background: Embryonic enamel matrix proteins are involved in the formation of acellular cementum during development of the periodontal attachment apparatus,…”
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Osteoblast-Mediated Mineral Deposition in Culture is Dependent on Surface Microtopography by Boyan, B.D., Bonewald, L.F., Paschalis, E.P., Lohmann, C.H., Rosser, J., Cochran, D.L., Dean, D.D., Schwartz, Z., Boskey, A.L.

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Ability of commercial demineralized freeze-dried bone allograft to induce new bone formation by Schwartz, Z, Mellonig, J T, Carnes, Jr, D L, de la Fontaine, J, Cochran, D L, Dean, D D, Boyan, B D

“…Demineralized freeze-dried bone allograft (DFDBA) has been used extensively in periodontal therapy. The rationale for use of DFDBA includes the fact that…”
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Evaluation of a prototype trilayer membrane (PTLM) for lateral ridge augmentation: an experimental study in the canine mandible by von Arx, T., Cochran, D.L., Schenk, R.K., Buser, D.

“…The objective of this animal study was to evaluate a biodegradable/bioresorbable prototype trilayer membrane (PTLM) consisting of two collagen layers and an…”
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Effects of Bisphosphonate on Matrix Metalloproteinase Enzymes in Human Periodontal Ligament Cells by Nakaya, H., Osawa, G., Iwasaki, N., Cochran, D.L., Kamoi, K., Oates, T.W.

“…Background: The host response is a critical component in the pathogenesis of periodontitis. In fact, the clinical benefits associated with regulating the host…”
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Effects of Periodontal Therapy on Rate of Preterm Delivery: A Randomized Controlled Trial by Offenbacher, S, Beck, J.D, Jared, H.L, Mauriello, S.M, Mendoza, L.C, Couper, D.J, Stewart, D.D, Murtha, A.P, Cochran, D.L, Dudley, D.J, Reddy, M.S, Geurs, N.C, Hauth, J.C

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Effect of porcine fetal enamel matrix derivative on chondrocyte proliferation, differentiation, and local factor production is dependent on cell maturation state by Dean, D D, Lohmann, C H, Sylvia, V L, Cochran, D L, Liu, Y, Boyan, B D, Schwartz, Z

“…Recent studies have shown that porcine fetal enamel matrix derivative (EMD) can enhance the osteoinductive ability of demineralized freeze-dried bone allograft…”
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Growth factor effects on the expression of collagenase and TIMP-1 in periodontal ligament cells by Alvares, O, Klebe, R, Grant, G, Cochran, D L

“…The fibroblast is a prominent cellular component of the periodontal ligament. It is believed to play an important role in collagen metabolism in health and…”
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A Randomized Clinical Trial Evaluating rh-FGF-2/β-TCP in Periodontal Defects by Cochran, D.L., Oh, T.-J., Mills, M.P., Clem, D.S., McClain, P.K., Schallhorn, R.A., McGuire, M.K., Scheyer, E.T., Giannobile, W.V., Reddy, M.S., Abou-Arraj, R.V., Vassilopoulos, P.J., Genco, R.J., Geurs, N.C., Takemura, A.

“…Biological mediators have been used to enhance periodontal regeneration. The aim of this prospective randomized controlled study was to evaluate the safety and…”
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Integrin α2β1 plays a critical role in osteoblast response to micron-scale surface structure and surface energy of titanium substrates by Olivares-Navarrete, R, Raz, P, Zhao, G, Chen, J, Wieland, M, Cochran, D.L, Chaudhri, R.A, Ornoy, A, Boyan, B.D, Schwartz, Z

“…Efforts to improve bone response to biomaterials have focused on ligands that bind α5β1 integrins. However, antibodies to α5β1 reduce osteoblast proliferation…”
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Mechanisms regulating increased production of osteoprotegerin by osteoblasts cultured on microstructured titanium surfaces by Schwartz, Zvi, Olivares-Navarrete, Rene, Wieland, Marco, Cochran, David L, Boyan, Barbara D

“…Abstract Osteoblasts grown on microstructured Ti surfaces enhance osteointegration by producing local factors that regulate bone formation as well as bone…”
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Development and Characterization of a Transformed Human Periodontal Ligament Cell Line by Hoang, A.M., Chen, D., Oates, T.W., Jiang, C., Harris, S.E., Cochran, D.L.

“…Periodontal ligament (pdl) cells are thought to be important for establishing and maintaining a stable interface between bone and teeth. In addition, PDL cells…”
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