Search Results - "Cocco, Tiziana"

PGC-1s in the Spotlight with Parkinson's Disease by Piccinin, Elena, Sardanelli, Anna Maria, Seibel, Peter, Moschetta, Antonio, Cocco, Tiziana, Villani, Gaetano

“…Parkinson's disease is one of the most common neurodegenerative disorders worldwide, characterized by a progressive loss of dopaminergic neurons mainly…”
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Effect of resveratrol on mitochondrial function: Implications in parkin-associated familiar Parkinson's disease by Ferretta, Anna, Gaballo, Antonio, Tanzarella, Paola, Piccoli, Claudia, Capitanio, Nazzareno, Nico, Beatrice, Annese, Tiziana, Di Paola, Marco, Dell'Aquila, Claudia, De Mari, Michele, Ferranini, Ermanno, Bonifati, Vincenzo, Pacelli, Consiglia, Cocco, Tiziana

“…Mitochondrial dysfunction and oxidative stress occur in Parkinson's disease (PD), but the molecular mechanisms controlling these events are not completely…”
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Phytochemicals from Red Onion, Grown with Eco-Sustainable Fertilizers, Protect Mammalian Cells from Oxidative Stress, Increasing Their Viability by Matrella, Maria Laura, Valletti, Alessio, Marra, Federica, Mallamaci, Carmelo, Cocco, Tiziana, Muscolo, Adele

“…Red onion, a species of great economic importance rich in phytochemicals (bioactive compounds) known for its medicinal properties, was fertilized with…”
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cAMP/PKA Signaling Modulates Mitochondrial Supercomplex Organization by Signorile, Anna, Pacelli, Consiglia, Palese, Luigi Leonardo, Santeramo, Arcangela, Roca, Emilio, Cocco, Tiziana, De Rasmo, Domenico

“…The oxidative phosphorylation (OXPHOS) system couples the transfer of electrons to oxygen with pumping of protons across the inner mitochondrial membrane,…”
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High OXPHOS efficiency in RA-FUdr-differentiated SH-SY5Y cells: involvement of cAMP signalling and respiratory supercomplexes by Matrella, Maria Laura, Valletti, Alessio, Gigante, Isabella, De Rasmo, Domenico, Signorile, Anna, Russo, Silvia, Lobasso, Simona, Lobraico, Donatella, Dibattista, Michele, Pacelli, Consiglia, Cocco, Tiziana

“…Neurons are highly dependent on mitochondria to meet their bioenergetic needs and understanding the metabolic changes during the differentiation process is…”
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Parkin Mutation Affects Clock Gene-Dependent Energy Metabolism by Pacelli, Consiglia, Rotundo, Giovannina, Lecce, Lucia, Menga, Marta, Bidollari, Eris, Scrima, Rosella, Cela, Olga, Piccoli, Claudia, Cocco, Tiziana, Vescovi, Angelo Luigi, Mazzoccoli, Gianluigi, Rosati, Jessica, Capitanio, Nazzareno

“…Growing evidence highlights a tight connection between circadian rhythms, molecular clockworks, and mitochondrial function. In particular, mitochondrial…”
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Tomatine Displays Antitumor Potential in In Vitro Models of Metastatic Melanoma by Serratì, Simona, Porcelli, Letizia, Guida, Stefania, Ferretta, Anna, Iacobazzi, Rosa Maria, Cocco, Tiziana, Maida, Immacolata, Tamasi, Gabriella, Rossi, Claudio, Manganelli, Michele, Tommasi, Stefania, Azzariti, Amalia, Guida, Gabriella

“…There is a growing interest in the cytotoxic effects of bioactive glycoalkaloids, such as α-tomatine on tumor cells. Here, for the first time, we determine the…”
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Lipidomics of intact mitochondria by MALDI-TOF/MS by Angelini, Roberto, Vitale, Rita, Patil, Vinay A., Cocco, Tiziana, Ludwig, Bernd, Greenberg, Miriam L., Corcelli, Angela

“…A simple and fast method of lipid analysis of isolated intact mitochondria by means of MALDI-TOF mass spectrometry is described. Mitochondria isolated from…”
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Synergistic Effect of Mitochondrial and Lysosomal Dysfunction in Parkinson's Disease by Guerra, Flora, Girolimetti, Giulia, Beli, Raffaella, Mitruccio, Marco, Pacelli, Consiglia, Ferretta, Anna, Gasparre, Giuseppe, Cocco, Tiziana, Bucci, Cecilia

“…Crosstalk between lysosomes and mitochondria plays a central role in Parkinson's Disease (PD). Lysosomal function may be influenced by mitochondrial quality…”
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Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy by Celestini, Valentina, Tezil, Tugsan, Russo, Luciana, Fasano, Candida, Sanese, Paola, Forte, Giovanna, Peserico, Alessia, Lepore Signorile, Martina, Longo, Giovanna, De Rasmo, Domenico, Signorile, Anna, Gadaleta, Raffaella Maria, Scialpi, Natasha, Terao, Mineko, Garattini, Enrico, Cocco, Tiziana, Villani, Gaetano, Moschetta, Antonio, Grossi, Valentina, Simone, Cristiano

“…While aberrant cancer cell growth is frequently associated with altered biochemical metabolism, normal mitochondrial functions are usually preserved and…”
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Resveratrol Treatment in Human Parkin -Mutant Fibroblasts Modulates cAMP and Calcium Homeostasis Regulating the Expression of Mitochondria-Associated Membranes Resident Proteins by Signorile, Anna, Ferretta, Anna, Pacelli, Consiglia, Capitanio, Nazzareno, Tanzarella, Paola, Matrella, Maria Laura, Valletti, Alessio, De Rasmo, Domenico, Cocco, Tiziana

“…Parkin plays an important role in ensuring efficient mitochondrial function and calcium homeostasis. -mutant human fibroblasts, with defective oxidative…”
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Pathogenic role of oxidative and nitrosative stress in primary biliary cirrhosis by Grattagliano, Ignazio, Calamita, Giuseppe, Cocco, Tiziana, Wang, David Q-H, Portincasa, Piero

“…Primary biliary cirrhosis is a multifactor autoimmune disease characterized by hepatic and systemic manifestations,with immune system dysregulation and…”
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Translational control mechanisms in cutaneous malignant melanoma: the role of eIF2α by Maida, Immacolata, Zanna, Paola, Guida, Stefania, Ferretta, Anna, Cocco, Tiziana, Palese, Luigi Leonardo, Londei, Paola, Benelli, Dario, Azzariti, Amalia, Tommasi, Stefania, Guida, Michele, Pellacani, Giovanni, Guida, Gabriella

“…Melanoma cells develop adaptive responses in order to cope with particular conditions of tumor microenvironment, characterized by stress conditions and…”
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TNFα signals via p66(Shc) to induce E-Selectin, promote leukocyte transmigration and enhance permeability in human endothelial cells by Laviola, Luigi, Orlando, Maura Roberta, Incalza, Maria Angela, Caccioppoli, Cristina, Melchiorre, Mariangela, Leonardini, Anna, Cignarelli, Angelo, Tortosa, Federica, Labarbuta, Rossella, Martemucci, Sabina, Pacelli, Consiglia, Cocco, Tiziana, Perrini, Sebastio, Natalicchio, Annalisa, Giorgino, Francesco

“…Endothelial cells participate in inflammatory events leading to atherogenesis by regulating endothelial cell permeability via the expression of VE-Cadherin and…”
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Increased Levels of cAMP by the Calcium-Dependent Activation of Soluble Adenylyl Cyclase in Parkin -Mutant Fibroblasts by Tanzarella, Paola, Ferretta, Anna, Barile, Simona Nicol, Ancona, Mariella, De Rasmo, Domenico, Signorile, Anna, Papa, Sergio, Capitanio, Nazzareno, Pacelli, Consiglia, Cocco, Tiziana

“…Almost half of autosomal recessive early-onset parkinsonism has been associated with mutations in , coding for parkin, which plays an important role in…”
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Mitochondrial oxidative alterations following partial hepatectomy by Guerrieri, Ferruccio, Vendemiale, Gianluigi, Grattagliano, Ignazio, Cocco, Tiziana, Pellecchia, Giovanna, Altomare, Emanuele

“…Mitochondria, isolated from rat livers during the early phase of liver regeneration (7–24 h after partial hepatectomy), show: (i) decrease in the rate of ATP…”
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The nuclear-encoded 18 kDa (IP) AQDQ subunit of bovine heart complex I is phosphorylated by the mitochondrial cAMP-dependent protein kinase by Papa, Sergio, Sardanelli, Anna Maria, Cocco, Tiziana, Speranza, Francesco, Scacco, Salvatore C., Technikova-Dobrova, Zuzana

“…In bovine heart mitochondria a protein of M r 18 kDa, phosphorylated by mtPKA, is associated to the NADH-ubiquinone oxidoreductase in the inner membrane and is…”
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Lipid profiling of parkin‐mutant human skin fibroblasts by Lobasso, Simona, Tanzarella, Paola, Vergara, Daniele, Maffia, Michele, Cocco, Tiziana, Corcelli, Angela

“…Parkin mutations are a major cause of early‐onset Parkinson's disease (PD). The impairment of protein quality control system together with defects in…”
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Antioxidant and Antitumor Activity of a Bioactive Polyphenolic Fraction Isolated from the Brewing Process by Tatullo, Marco, Simone, Grazia Maria, Tarullo, Franco, Irlandese, Gianfranco, Vito, Danila De, Marrelli, Massimo, Santacroce, Luigi, Cocco, Tiziana, Ballini, Andrea, Scacco, Salvatore

“…There is increasing interest in identifying natural bioactive compounds that can improve mitochondrial functionality and regulate apoptosis. The brewery…”
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New insight into the role of metabolic reprogramming in melanoma cells harboring BRAF mutations by Ferretta, Anna, Maida, Immacolata, Guida, Stefania, Azzariti, Amalia, Porcelli, Letizia, Tommasi, Stefania, Zanna, Paola, Cocco, Tiziana, Guida, Michele, Guida, Gabriella

“…This study explores the V600BRAF-MITF-PGC-1α axis and compares metabolic and functional changes occurring in primary and metastatic V600BRAF melanoma cell…”
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