Search Results - "Coburn, Peyton T."
-
1
Gys1 Antisense Therapy Prevents Disease-Driving Aggregates and Epileptiform Discharges in a Lafora Disease Mouse Model
Published in Neurotherapeutics (01-10-2023)“…Patients with Lafora disease have a mutation in EPM2A or EPM2B , resulting in dysregulation of glycogen metabolism throughout the body and aberrant glycogen…”
Get full text
Journal Article -
2
Extracellular vesicle transfer of miR-1 to adipose tissue modifies lipolytic pathways following resistance exercise
Published in JCI insight (08-11-2024)“…Extracellular vesicles (EVs) have emerged as important mediators of inter-tissue signaling and exercise adaptations. In this human study (n = 32), we provide…”
Get full text
Journal Article -
3
In situ microwave fixation provides an instantaneous snapshot of the brain metabolome
Published in Cell reports methods (24-04-2023)“…Brain glucose metabolism is highly heterogeneous among brain regions and continues postmortem. In particular, we demonstrate exhaustion of glycogen and glucose…”
Get full text
Journal Article