Search Results - "Cobos, María Jover"
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L‐ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure
Published in Hepatology (Baltimore, Md.) (01-07-2009)“…Hyperammonemia is a feature of acute liver failure (ALF), which is associated with increased intracranial pressure (ICP) and brain herniation. We hypothesized…”
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Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells
Published in Nature medicine (01-06-2015)“…Pallett et al. report that myeloid derived suppressor cells expand, home to the liver, and inhibit T cell-mediated liver damage in chronic hepatitis B virus…”
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Increased renal expression and urinary excretion of TLR4 in acute kidney injury associated with cirrhosis
Published in Liver international (01-03-2013)“…Background Patients with cirrhosis frequently develop renal dysfunction, a proportion of who do not fulfill criteria for hepatorenal syndrome (HRS). We…”
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Role of Toll‐Like Receptor 4 in Mediating Multiorgan Dysfunction in Mice With Acetaminophen Induced Acute Liver Failure
Published in Liver transplantation (01-07-2013)“…Strategies for the prevention of multiorgan dysfunction (MOD) in acetaminophen (APAP)‐induced acute liver failure (ALF) are an unmet need. Our study tested the…”
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The brain in acute on chronic liver failure
Published in Metabolic brain disease (01-12-2014)“…Acute-on-chronic liver failure (ACLF) is a newly defined clinical entity with significant morbidity and mortality (~40–90 % at 1 year dependent on need for…”
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Treatment of hyperammonemia in liver failure
Published in Current opinion in clinical nutrition and metabolic care (01-01-2014)“…PURPOSE OF REVIEWHyperammonemia is thought to be central in the pathophysiology of hepatic encephalopathy in patients suffering from liver failure. The purpose…”
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Prevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression
Published in Journal of hepatology (01-05-2012)“…Background & Aims Superimposed infection and/or inflammation precipitate renal failure in cirrhosis. This study aimed at testing the hypothesis that increased…”
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Ornithine phenylacetate revisited
Published in Metabolic brain disease (01-06-2013)“…In patients with liver failure hyperammonemia is associated with the development of hepatic encephalopathy (HE) and immune impairment. Treatment of…”
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Increased renal expression and urinary excretion of TLR 4 in acute kidney injury associated with cirrhosis
Published in Liver international (01-03-2013)“…Abstract Background Patients with cirrhosis frequently develop renal dysfunction, a proportion of who do not fulfill criteria for hepatorenal syndrome ( HRS )…”
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Journal Article