Search Results - "Cobo‐Vuilleumier, Nadia"

Thyroid hormones in diabetes, cancer, and aging by Gauthier, Benoit R., Sola‐García, Alejandro, Cáliz‐Molina, María Ángeles, Lorenzo, Petra Isabel, Cobo‐Vuilleumier, Nadia, Capilla‐González, Vivian, Martin‐Montalvo, Alejandro

“…Thyroid hormones are central in the control of health and disease. Here we review the latest findings in thyroid hormone research in the field of diabetes,…”
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Molecular Modelling of Islet β-Cell Adaptation to Inflammation in Pregnancy and Gestational Diabetes Mellitus by Lorenzo, Petra I, Martín-Montalvo, Alejandro, Cobo Vuilleumier, Nadia, Gauthier, Benoit R

“…Gestational diabetes mellitus (GDM), a metabolic disease that develops with the increase in insulin resistance during late pregnancy, is currently one of the…”
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Harnessing the Endogenous Plasticity of Pancreatic Islets: A Feasible Regenerative Medicine Therapy for Diabetes? by Lorenzo, Petra I, Cobo-Vuilleumier, Nadia, Martín-Vázquez, Eugenia, López-Noriega, Livia, Gauthier, Benoit R

“…Diabetes is a chronic metabolic disease caused by an absolute or relative deficiency in functional pancreatic β-cells that leads to defective control of blood…”
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Roles of extracellular vesicles associated non-coding RNAs in Diabetes Mellitus by Gauthier, Benoit R, Cobo-Vuilleumier, Nadia, López-Noriega, Livia

“…Extracellular vesicles (EVs), especially exosomes (50 to 150 nm), have been shown to play important roles in a wide range of physiological and pathological…”
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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus by Cobo-Vuilleumier, Nadia, Lorenzo, Petra I., Rodríguez, Noelia García, Herrera Gómez, Irene de Gracia, Fuente-Martin, Esther, López-Noriega, Livia, Mellado-Gil, José Manuel, Romero-Zerbo, Silvana-Yanina, Baquié, Mathurin, Lachaud, Christian Claude, Stifter, Katja, Perdomo, German, Bugliani, Marco, De Tata, Vincenzo, Bosco, Domenico, Parnaud, Geraldine, Pozo, David, Hmadcha, Abdelkrim, Florido, Javier P., Toscano, Miguel G., de Haan, Peter, Schoonjans, Kristina, Sánchez Palazón, Luis, Marchetti, Piero, Schirmbeck, Reinhold, Martín-Montalvo, Alejandro, Meda, Paolo, Soria, Bernat, Bermúdez-Silva, Francisco-Javier, St-Onge, Luc, Gauthier, Benoit R.

“…Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies focused on repressing the immune…”
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Levothyroxine enhances glucose clearance and blunts the onset of experimental type 1 diabetes mellitus in mice by López‐Noriega, Livia, Cobo‐Vuilleumier, Nadia, Narbona‐Pérez, Álvaro Jesús, Araujo‐Garrido, Juan Luis, Lorenzo, Petra Isabel, Mellado‐Gil, José Manuel, Moreno, José Carlos, Gauthier, Benoit R, Martín‐Montalvo, Alejandro

“…Background and Purpose Thyroid hormones induce several changes in whole body metabolism that are known to improve metabolic homeostasis. However, adverse side…”
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Abnormal cannabidiol ameliorates inflammation preserving pancreatic beta cells in mouse models of experimental type 1 diabetes and beta cell damage by González-Mariscal, Isabel, Pozo-Morales, Macarena, Romero-Zerbo, Silvana Y., Espinosa-Jimenez, Vanesa, Escamilla-Sánchez, Alejandro, Sánchez-Salido, Lourdes, Cobo-Vuilleumier, Nadia, Gauthier, Benoit R., Bermúdez-Silva, Francisco J.

“…The atypical cannabinoid Abn-CBD improves the inflammatory status in preclinical models of several pathologies, including autoimmune diseases. However, its…”
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The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease by Romero-Zerbo, Silvana Y, García-Fernández, María, Espinosa-Jiménez, Vanesa, Pozo-Morales, Macarena, Escamilla-Sánchez, Alejandro, Sánchez-Salido, Lourdes, Lara, Estrella, Cobo-Vuilleumier, Nadia, Rafacho, Alex, Olveira, Gabriel, Rojo-Martínez, Gemma, Gauthier, Benoit R, González-Mariscal, Isabel, Bermúdez-Silva, Francisco J

“…The synthetic atypical cannabinoid Abn-CBD, a cannabidiol (CBD) derivative, has been recently shown to modulate the immune system in different organs, but its…”
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The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice by Romero-Zerbo, Silvana Y., Ruz-Maldonado, Inmaculada, Espinosa-Jiménez, Vanesa, Rafacho, Alex, Gómez-Conde, Ana I., Sánchez-Salido, Lourdes, Cobo-Vuilleumier, Nadia, Gauthier, Benoit R., Tinahones, Francisco J., Persaud, Shanta J., Bermúdez-Silva, Francisco J.

“…LH-21 is a triazol derivative that has been described as a low-permeant neutral CB1 antagonist, though its pharmacology is still unclear. It has been…”
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Immunohistochemical assessment of Pax8 expression during pancreatic islet development and in human neuroendocrine tumors by Lorenzo, Petra I., Jimenez Moreno, Carmen M., Delgado, Irene, Cobo-Vuilleumier, Nadia, Meier, Raphael, Gomez-Izquierdo, Lourdes, Berney, Thierry, Garcia-Carbonero, Rocio, Rojas, Anabel, Gauthier, Benoit R.

“…The paired box transcription factor Pax8 is critical for development of the eye, thyroid gland as well as the urinary and reproductive organs. In adult, Pax8…”
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NR5A2/LRH-1 regulates the PTGS2-PGE2-PTGER1 pathway contributing to pancreatic islet survival and function by Martin Vázquez, Eugenia, Cobo-Vuilleumier, Nadia, Araujo Legido, Raquel, Marín-Cañas, Sandra, Nola, Emanuele, Dorronsoro, Akaitz, López Bermudo, Lucia, Crespo, Alejandra, Romero-Zerbo, Silvana Y., García-Fernández, Maria, Martin Montalvo, Alejandro, Rojas, Anabel, Comaills, Valentine, Bérmudez-Silva, Francisco J., Gannon, Maureen, Martin, Franz, Eizirik, Decio, Lorenzo, Petra I., Gauthier, Benoit R.

“…LRH-1/NR5A2 is implicated in islet morphogenesis postnatally, and its activation using the agonist BL001 protects islets against apoptosis, reverting…”
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Targeting LRH-1/NR5A2 to treat type 1 diabetes mellitus by Cobo-Vuilleumier, Nadia, Lorenzo, Petra I, Gauthier, Benoit R

“…Type 1 diabetes mellitus (T1DM) is defined as an autoimmune disease that targets the selective destruction of islet insulin-producing beta cells by…”
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Dissecting the Brain/Islet Axis in Metabesity by Fuente-Martín, Esther, Mellado-Gil, Jose M, Cobo-Vuilleumier, Nadia, Martín-Montalvo, Alejandro, Romero-Zerbo, Silvana Y, Diaz Contreras, Irene, Hmadcha, Abdelkrim, Soria, Bernat, Martin Bermudo, Francisco, Reyes, Jose C, Bermúdez-Silva, Francisco J, Lorenzo, Petra I, Gauthier, Benoit R

“…The high prevalence of type 2 diabetes mellitus (T2DM), together with the fact that current treatments are only palliative and do not avoid major secondary…”
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Clinical Heterogeneity in Monogenic Diabetes Caused by Mutations in the Glucokinase Gene (GCK-MODY) by Cuesta-Muñoz, Antonio L, Tuomi, Tiinamaija, Cobo-Vuilleumier, Nadia, Koskela, Hanna, Odili, Stella, Stride, Amanda, Buettger, Carol, Otonkoski, Timo, Froguel, Philippe, Grimsby, Joseph, Garcia-Gimeno, Maria, Matschinsky, Franz M

“…OBJECTIVE: To evaluate the heterogeneity in the clinical expression in a family with glucokinase mature-onset diabetes of the young (GCK-MODY). RESEARCH DESIGN…”
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Corrigendum to “Islet β-Cell Mass Preservation and Regeneration in Diabetes Mellitus: Four Factors with Potential Therapeutic Interest” by Mellado-Gil, Jose Manuel, Gauthier, Benoit R., Cobo-Vuilleumier, Nadia

“…In the article titled “Islet β-Cell Mass Preservation and Regeneration in Diabetes Mellitus: Four Factors with Potential Therapeutic Interest” [1], a grant…”
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A Simple High Efficiency Intra-Islet Transduction Protocol Using Lentiviral Vectors by Jimenez-Moreno, Carmen Maria, Herrera-Gomez, Irene de Gracia, Lopez-Noriega, Livia, Lorenzo, Petra Isabel, Cobo-Vuilleumier, Nadia, Fuente-Martin, Esther, Mellado-Gil, Jose Manuel, Parnaud, Geraldine, Bosco, Domenico, Gauthier, Benoit Raymond, Martin-Montalvo, Alejandro

“…Successful normalization of blood glucose in patients transplanted with pancreatic islets isolated from cadaveric donors established the proof-of-concept that…”
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Time for a paradigm shift in treating type 1 diabetes mellitus: coupling inflammation to islet regeneration by Cobo-Vuilleumier, Nadia, Gauthier, Benoit R.

“…Type 1 diabetes mellitus (T1DM) is an autoimmune disease that targets the destruction of islet beta-cells resulting in insulin deficiency, hyperglycemia and…”
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Islet β-Cell Mass Preservation and Regeneration in Diabetes Mellitus: Four Factors with Potential Therapeutic Interest by Mellado-Gil, Jose Manuel, Cobo-Vuilleumier, Nadia, Gauthier, Benoit R

“…Islet β-cell replacement and regeneration are two promising approaches for the treatment of Type 1 Diabetes Mellitus. Indeed, the success of islet…”
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The PTGS2/COX2-PGE2 signaling cascade in inflammation: Pro or anti? A case study with type 1 diabetes mellitus by Martín-Vázquez, Eugenia, Cobo-Vuilleumier, Nadia, López-Noriega, Livia, Lorenzo, Petra I, Gauthier, Benoit R

“…Prostaglandins are lipid mediators involved in physiological processes, such as constriction or dilation of blood vessels, but also pathophysiological…”
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The PTGS2/COX2-PGE 2 signaling cascade in inflammation: Pro or anti? A case study with type 1 diabetes mellitus by Martín-Vázquez, Eugenia, Cobo-Vuilleumier, Nadia, López-Noriega, Livia, Lorenzo, Petra I., Gauthier, Benoit R.

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