Search Results - "Coatti, Giuliana C"
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Genistein Affects Expression of Cytochrome P450 (CYP450) Genes in Hepatocellular Carcinoma (HEPG2/C3A) Cell Line
Published in Drug metabolism letters (2018)“…Genistein (5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) is the most abundant isoflavone in soybean, which has been associated with a lower risk of…”
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Dual SMAD inhibition enhances the longevity of human epididymis epithelial cells
Published in Cell and tissue research (01-02-2023)“…Primary human epididymis epithelial (HEE) cells are valuable reagents for functional studies on the human epididymis. We used them previously to determine the…”
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A promoter-dependent upstream activator augments CFTR expression in diverse epithelial cell types
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-06-2024)“…The cystic fibrosis transmembrane conductance regulator (CFTR) gene encodes an anion-selective channel found in epithelial cell membranes. Mutations in CFTR…”
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The impact of genomic distance on enhancer‐promoter interactions at the CFTR locus
Published in Journal of cellular and molecular medicine (01-02-2024)“…We identified and characterized multiple cell‐type selective enhancers of the CFTR gene promoter in previous work and demonstrated active looping of these…”
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An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
Published in Journal of neuroscience research (01-01-2021)“…ACTL6B is a component of the neuronal BRG1/brm‐associated factor (nBAF) complex, which is required for chromatin remodeling in postmitotic neurons. We recently…”
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Random changepoint segmented regression with smooth transition
Published in Statistical methods in medical research (01-03-2021)“…We consider random changepoint segmented regression models to analyse data from a study conducted to verify whether treatment with stem cells may delay the…”
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Overexpression of KLC2 due to a homozygous deletion in the non-coding region causes SPOAN syndrome
Published in Human molecular genetics (15-12-2015)“…SPOAN syndrome is a neurodegenerative disorder mainly characterized by spastic paraplegia, optic atrophy and neuropathy (SPOAN). Affected patients are…”
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