Search Results - "Coats, B. S."

Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors by Dunbar, E. M., Coats, B. S., Shroads, A. L., Langaee, T., Lew, A., Forder, J. R., Shuster, J. J., Wagner, D. A., Stacpoole, P. W.

“…Summary Background Recurrent malignant brain tumors (RMBTs) carry a poor prognosis. Dichloroacetate (DCA) activates mitochondrial oxidative metabolism and has…”
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Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children by Shroads, A. L., Coats, B. S., McDonough, C. W., Langaee, T., Stacpoole, P. W.

“…Dichloroacetate (DCA) is biotransformed by glutathione transferase zeta 1 (GSTZ1), a bifunctional enzyme that, as maleylacetoacetate isomerase (MAAI),…”
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Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor by Davis, Steven R, Stacpoole, Peter W, Williamson, Jerry, Kick, Lilia S, Quinlivan, Eoin P, Coats, Bonnie S, Shane, Barry, Bailey, Lynn B, Gregory, 3rd, Jesse F

“…Hyperhomocysteinemia in humans is associated with genetic variants of several enzymes of folate and one-carbon metabolism and deficiencies of folate and…”
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Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and men by Davis, S.R, Scheer, J.B, Quinlivan, E.P, Coats, B.S, Stacpoole, P.W, Gregory, J.F. III

“…Background: The effects of vitamin B-6 status on steady-state kinetics of homocysteine metabolism in humans are unclear. Objective: The objective was to…”
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The methylenetetrahydrofolate reductase 677C->T polymorphism and dietary folate restriction affect plasma one-carbon metabolites and red blood cell folate concentrations and distribution in women by Davis, Steven R, Quinlivan, Eoin P, Shelnutt, Karla P, Maneval, David R, Ghandour, Haifa, Capdevila, Antonieta, Coats, Bonnie S, Wagner, Conrad, Selhub, Jacob, Bailey, Lynn B, Shuster, Jonathan J, Stacpoole, Peter W, Gregory, 3rd, Jesse F

“…Whether folate status and the methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism interact to affect methionine-cycle metabolite concentrations…”
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Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women by Davis, Steven R, Quinlivan, Eoin P, Shelnutt, Karla P, Ghandour, Haifa, Capdevila, Antonieta, Coats, Bonnie S, Wagner, Conrad, Shane, Barry, Selhub, Jacob, Bailey, Lynn B, Shuster, Jonathan J, Stacpoole, Peter W, Gregory, 3rd, Jesse F

“…The effects of folate status and the methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism on the kinetics of homocysteine metabolism are unclear…”
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Changes in psychological status and health-related quality of life following total shoulder arthroplasty by Cho, Chul-Hyun, MD, PhD, Coats-Thomas, Margaret S., BS, Warner, Jon J.P., MD

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Meta-Analysis of Apparent Diffusion Coefficients in the Newborn Brain by Coats, Jacqueline S., BA, Freeberg, Adam, MPH, Pajela, Elaine G., BS, Obenaus, André, PhD, Ashwal, Stephen, MD

“…Diffusion-weighted imaging and its quantitative apparent diffusion coefficient can assess severity in newborn hypoxic-ischemic injuries. A meta-analysis…”
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Assessment of painful total shoulder arthroplasty using computed tomography arthrography by Mallo, Gregory C., MD, Burton, Lauren, BA, Coats-Thomas, Margaret, BS, Daniels, S. David, BS, Sinz, Nathan J., BA, Warner, Jon J.P., MD

“…Background This study assessed the accuracy of computed tomography (CT) arthrography when evaluating glenoid component stability in the setting of…”
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