Search Results - "Coates, TD"

Placenta growth factor activates monocytes and correlates with sickle cell disease severity by Perelman, Natalya, Selvaraj, Suresh K., Batra, Sandeep, Luck, Lori R., Erdreich-Epstein, Anat, Coates, Thomas D., Kalra, Vijay K., Malik, Punam

“…Sickle cell disease (SCD) results in chronic hypoxia and secondarily increased erythropoietin concentrations. Leukocytosis and activated monocytes are also…”
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MRI R2 and R2 mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients by Wood, John C., Enriquez, Cathleen, Ghugre, Nilesh, Tyzka, J. Michael, Carson, Susan, Nelson, Marvin D., Coates, Thomas D.

“…Measurements of hepatic iron concentration (HIC) are important predictors of transfusional iron burden and long-term outcome in patients with…”
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The cost of health care for children and adults with sickle cell disease by Kauf, Teresa L., Coates, Thomas D., Huazhi, Liu, Mody‐Patel, Nikita, Hartzema, Abraham G.

“…Although sickle cell disease (SCD) is marked by high utilization of medical resources, the full cost of care for patients with SCD, including care not directly…”
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Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease by Wood, John C., Tyszka, J. Michael, Carson, Susan, Nelson, Marvin D., Coates, Thomas D.

“…Cardiac T2* (magnetic resonance imaging relaxation parameter) is abnormally low in approximately 40% of adults with thalassemia major (TM), suggesting…”
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Cardiac iron determines cardiac T2, T2, and T1 in the gerbil model of iron cardiomyopathy by WOOD, John C, OTTO-DUESSEL, Maya, AGUILAR, Michelle, NICK, Hanspeter, NELSON, Marvin D, COATES, Thomas D, POLLACK, Harvey, MOATS, Rex

“…Transfusional therapy for thalassemia major and sickle cell disease can lead to iron deposition and damage to the heart, liver, and endocrine organs. Iron…”
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Improved R2 measurements in myocardial iron overload by Ghugre, Nilesh R., Enriquez, Cathleen M., Coates, Thomas D., Nelson Jr, Marvin D., Wood, John C.

“…Purpose To optimize R2*(1/T2*) measurements for cardiac iron detection in sickle cell and thalassemia patients. Materials and Methods We studied 31 patients…”
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The effect of hypnosis on pain and peripheral blood flow in sickle-cell disease: a pilot study by Bhatt, Ravi R, Martin, Sarah R, Evans, Subhadra, Lung, Kirsten, Coates, Thomas D, Zeltzer, Lonnie K, Tsao, Jennie C

“…Vaso-occlusive pain crises (VOCs) are the "hallmark" of sickle-cell disease (SCD) and can lead to sympathetic nervous system dysfunction. Increased sympathetic…”
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Physiology and Pathophysiology of Iron Cardiomyopathy in Thalassemia by WOOD, JOHN C., ENRIQUEZ, CATHLEEN, GHUGRE, NILESH, OTTO-DUESSEL, MAYA, AGUILAR, MICHELLE, NELSON, MARVIN D., MOATS, REX, COATES, THOMAS D.

“…: Iron cardiomyopathy remains the leading cause of death in patients with thalassemia major. Magnetic resonance imaging (MRI) is ideally suited for monitoring…”
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Mechanisms of tissue-iron relaxivity: Nuclear magnetic resonance studies of human liver biopsy specimens by Ghugre, Nilesh R., Coates, Thomas D., Nelson, Marvin D., Wood, John C.

“…MRI is becoming an increasingly important tool to assess iron overload disorders, but the complex nature of proton–iron interactions has troubled noninvasive…”
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A novel cross-correlation methodology for assessing biophysical responses associated with pain by Sunwoo, John, Chalacheva, Patjanaporn, Khaleel, Maha, Shah, Payal, Sposto, Richard, Kato, Roberta M, Detterich, Jon, Zeltzer, Lonnie K, Wood, John C, Coates, Thomas D, Khoo, Michael Ck

“…The purpose of this work was to noninvasively detect and quantify microvascular blood flow changes in response to externally applied pain in humans. The…”
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Fetal haemoglobin augmentation in E/β° thalassaemia : clinical and haematological outcome by SINGER, Sylvia T, KUYPERS, Frans A, OLIVIERI, Nancy F, WEATHERALL, David J, MIGNACCA, Robert, COATES, Thomas D, DAVIES, Sally, SWEETERS, Nancy, VICHINSKY, Elliott P

“…Patients with E/beta(0) thalassaemia, the most common haemoglobinopathy in many Asian countries, might benefit from drugs that increase fetal and total…”
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PHM1 COST-EFFECTIVENESS OF ONCE-DAILY ORAL CHELATION THERAPY WITH DEFERASIROX VERSUS INFUSIONAL DEFEROXAMINE IN TRANSFUSION-DEPENDENT THALASSEMIA PATIENTS by Delea, T, Sofrygin, O, Thomas, S, Baladi, JF, Phatak, P, Coates, TD

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PHM4 COSTS AND CONSEQUENCES OF INADEQUATE COMPLIANCE WITH DEFEROXAMINE THERAPY IN PATIENTS WITH TRANSFUSION-DEPENDENT THALASSEMIA by Delea, T, Sofrygin, O, Thomas, S, Baladi, JF, Coates, TD, Phatak, P

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Sickle Erythrocytes Adhere to Polymorphonuclear Neutrophils and Activate the Neutrophil Respiratory Burst by Hofstra, Thomas C., Kalra, Vijay K., Meiselman, Herbert J., Coates, Thomas D.

“…The vasoocclusive process in patients with sickle cell disease (SCD) is complex and involves interactions among sickle erythrocytes (SS-RBC), vascular…”
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Classification of simple stimuli based on detected nerve activity by Coates, S.D., Larson-Prior, L.J., Wolpert, S., Prior, F.

“…Describes an interface and a signal processing methodology that use measured neural signals to image overall axonal activity in intact peripheral nerve. Since…”
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A practical approach to neutrophil disorders by Kyono, Wade, Coates, Thomas D

“…This review discusses disorders of altered neutrophil number and function and provide a basic framework for patient evaluation and management. The sections…”
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An In Vitro Model of Human Red Blood Cell Production From Hematopoietic Progenitor Cells by Malik, Punam, Fisher, Timothy C., Barsky, Lora L.W., Zeng, Licheng, Izadi, Parvin, Hiti, Alan L., Weinberg, Kenneth I., Coates, Thomas D., Meiselman, Herbert J., Kohn, Donald B.

“…Hemoglobinopathies, such as β-thalassemias and sickle cell anemia (SCA), are among the most common inherited gene defects. Novel models of human erythropoiesis…”
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Mechanism of cigarette smoke condensate induced adhesion of human monocytes to cultured endothelial cells by Kalra, V K, Ying, Y, Deemer, K, Natarajan, R, Nadler, J L, Coates, T D

“…Cigarette smoking is ranked among the leading risk factors in the etiology of atherosclerotic vascular disease. The mechanisms, however, that link cigarette…”
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Function of the cytoskeleton in human neutrophils and methods for evaluation by Torres, Martine, Coates, Thomas D

“…The cytoskeleton plays a critical role in the determination of cell shape and serves as a scaffold for critical cellular enzymes and adhesion molecules. It…”
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Control and monitoring of a parallel processed neural network via the World Wide Web by Coates, Thomas D

“…Training an artificial neural network (ANN) can be a time-consuming process. The training time can be decreased by implementing the network on a parallel…”
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