Search Results - "Co, Dominic O"
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Autoimmune Encephalitis: Distinguishing Features and Specific Therapies
Published in Critical care clinics (01-04-2022)“…Autoimmune encephalitis is characterized by subacute onset of the altered mental status that can rapidly progress to autonomic instability and refractory…”
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T Cell Interactions in Mycobacterial Granulomas: Non-Specific T Cells Regulate Mycobacteria-Specific T Cells in Granulomatous Lesions
Published in Cells (Basel, Switzerland) (24-11-2021)“…Infections with pathogenic mycobacteria are controlled by the formation of a unique structure known as a granuloma. The granuloma represents a host-pathogen…”
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Acquired Demyelinating Syndromes
Published in The Medical clinics of North America (01-01-2024)“…Acquired demyelinating syndromes (ADS) are a heterogenous group of inflammatory demyelinating conditions that include presentations of optic neuritis,…”
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Juvenile Dermatomyositis: Immunopathogenesis, Role of Myositis-Specific Autoantibodies, and Review of Rituximab Use
Published in Pediatric dermatology (01-07-2011)“…: Juvenile dermatomyositis (JDM) is an autoimmune disease of the skin and muscle that affects children. The etiology is poorly understood, but genetic…”
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Bilateral Rasmussen Encephalitis: Good Outcome Following Hemispherotomy
Published in Pediatric neurology (01-02-2024)“…Bilateral Rasmussen encephalitis is a rare variant of a debilitating, typically unihemispheric disease with limited treatment options. Few cases with bilateral…”
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Childhood-Onset Systemic Lupus Erythematosus
Published in Pediatrics in review (01-06-2024)Get full text
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New Medications Are Needed for Children With Juvenile Idiopathic Arthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2020)“…Objective To document the need for additional Food and Drug Administration (FDA)–approved medications for the treatment of juvenile idiopathic arthritis (JIA)…”
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Virally Activated CD8 T Cells Home to Mycobacterium bovis BCG-Induced Granulomas but Enhance Antimycobacterial Protection Only in Immunodeficient Mice
Published in Infection and Immunity (01-03-2007)“…The effect of secondary infections on CD4 T-cell-regulated chronic granulomatous inflammation is not well understood. Here, we have investigated the effect of…”
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Disease Course, Treatments, and Outcomes of Children With Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease
Published in Arthritis care & research (2010) (01-03-2024)“…Objective Systemic juvenile idiopathic arthritis–associated lung disease (SJIA‐LD) is a life‐threatening disease complication. Key questions remain regarding…”
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Infection with Mycobacterium bovis BCG diverts traffic of myelin oligodendroglial glycoprotein autoantigen-specific T cells away from the central nervous system and ameliorates experimental autoimmune encephalomyelitis
Published in Clinical and diagnostic laboratory immunology (01-07-2003)“…Infectious agents have been proposed to influence susceptibility to autoimmune diseases such as multiple sclerosis. We induced a Th1-mediated central nervous…”
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Toxic Epidermal Necrolysis-Like Cutaneous Lupus in Pediatric Patients: A Case Series and Review
Published in Pediatrics (Evanston) (01-06-2016)“…Bullous eruptions in patients with underlying systemic lupus erythematosus (LE) can mimic toxic-epidermal necrolysis (TEN), a rapidly progressive mucocutaneous…”
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Methotrexate for inflammatory skin disease in pediatric patients: Consensus treatment guidelines
Published in Pediatric dermatology (01-09-2023)“…Methotrexate (MTX) is a readily accessible drug, first used in 1948 and employed for a wide variety of indications since then. However, despite widespread…”
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Clinical characteristics and management of clinically amyopathic juvenile dermatomyositis across four academic centers
Published in Pediatric dermatology (01-03-2021)“…Background/Objectives Clinically amyopathic juvenile dermatomyositis (CAJDM) is an uncommon but important subset of patients with juvenile dermatomyositis,…”
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Lipoatrophic panniculitis in an adolescent
Published in Pediatric dermatology (01-05-2020)“…Lipoatrophic panniculitis (LP) is a rare childhood panniculitis characterized by sclerotic, atrophic plaques on the extremities. We present a case of LP…”
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How Often are Pediatric Patients with Clinically Amyopathic Dermatomyositis Truly Amyopathic?
Published in Pediatric dermatology (01-01-2017)“…Background Pediatric patients can present with skin manifestations of dermatomyositis without overt weakness (clinically amyopathic juvenile dermatomyositis…”
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Immune-Mediated Diseases of the Central Nervous System: A Specificity-Focused Diagnostic Paradigm
Published in The Pediatric clinics of North America (01-02-2017)“…Immune-mediated diseases of the central nervous system show wide variability both symptomatically and with respect to underlying pathophysiology. Recognizing…”
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Hypergammaglobulinemic purpura of Waldenström in children
Published in Pediatric dermatology (01-05-2020)“…Background Hypergammaglobulinemic purpura of Waldenström (HGPW), a rare cutaneous eruption characterized by the triad of recurrent episodes of lower extremity…”
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Immune-Mediated Diseases of the Central Nervous System
Published in The Pediatric clinics of North America (01-02-2017)“…Immune-mediated diseases of the central nervous system show wide variability both symptomatically and with respect to underlying pathophysiology. Recognizing…”
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Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression
Published in The Journal of immunology (1950) (01-12-2013)“…To study regulatory T (Treg) cell control of chronic autoimmunity in a lymphoreplete host, we created and characterized a new model of autoimmune lung…”
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