Search Results - "Cmelik, Richard"
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Adamantane-Substituted Purines and Their β-Cyclodextrin Complexes: Synthesis and Biological Activity
Published in International journal of molecular sciences (24-11-2021)“…Cyclin-dependent kinases (CDKs) play an important role in the cell-division cycle. Synthetic inhibitors of CDKs are based on 2,6,9-trisubstituted purines and…”
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Sulfate supplementation affects nutrient and photosynthetic status of Arabidopsis thaliana and Nicotiana tabacum differently under prolonged exposure to cadmium
Published in Journal of hazardous materials (05-03-2023)“…Hydroponic experiments were performed to examine the effect of prolonged sulfate limitation combined with cadmium (Cd) exposure in Arabidopsis thaliana and a…”
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Enzybiotics LYSSTAPH-S and LYSDERM-S as Potential Therapeutic Agents for Chronic MRSA Wound Infections
Published in Antibiotics (Basel) (01-08-2020)“…Antibacterial antibiotic therapy has played an important role in the treatment of bacterial infections for almost a century. The increasing resistance of…”
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Fluorescein-based low-molecular-mass markers of isoelectric point for tracing pH gradient using high sensitivity capillary isoelectric focusing with laser-induced fluorescence detection
Published in Analytica chimica acta (01-12-2024)“…Successful implementation of capillary isoelectric focusing (cIEF) in general requires the use of reference points - markers of isoelectric point. The…”
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Novel adamantane-bearing anilines and properties of their supramolecular complexes with β-cyclodextrin
Published in Supramolecular chemistry (01-10-2011)“…Several novel anilines bearing 1-adamantyl substituents that are useful for drug modification were synthesised from the corresponding 1-adamantyl (nitrophenyl)…”
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Different behavior of dextrans in positive-ion and negative-ion mass spectrometry
Published in Journal of mass spectrometry (01-12-2004)“…A mass spectrometric (MS) comparative study of dextran samples using two different ionization techniques (matrix‐assisted laser desorption/ionization (MALDI)…”
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Adamantane-bearing benzylamines and benzylamides: novel building blocks for supramolecular systems with finely tuned binding properties towards β-cyclodextrin
Published in Supramolecular chemistry (01-06-2013)“…Novel building blocks for the synthesis of supramolecular components based on adamantane-bearing benzylamines were prepared. The binding properties of these…”
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Labeling strategies for analysis of oligosaccharides and glycans by capillary electrophoresis
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-06-2023)“…Capillary electrophoresis represents a powerful separation technique that has been widely accepted in oligosaccharide and glycan analysis. However, due to…”
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No‐additive salting‐out liquid–liquid extraction—A tool for purification of positively charged compounds from highly salted reaction mixtures
Published in Journal of separation science (01-12-2020)“…A novel and original application of salting‐out assisted liquid–liquid extraction is presented. This technique was used to purify the final reaction products…”
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Determination of short-term changes in levoglucosan and dehydroabietic acid in aerosols with Condensation Growth Unit – Aerosol Counterflow Two-Jets Unit – LC-MS
Published in Chemosphere (Oxford) (01-11-2018)“…Residential areas in urban agglomerations and also in the countryside are often burdened with high concentrations of aerosol in winter, this originating from…”
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Comparison of oligosaccharide labeling employing reductive amination and hydrazone formation chemistries
Published in Electrophoresis (01-05-2020)“…In this work, we compare labeling by two negatively charged fluorescent labels, 8‐aminopyrene‐1,3,6‐trisulfonic acid (APTS) and…”
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Characterization of multi‐cationic aminopyrene‐based tag for oligosaccharide labeling by capillary electrophoresis with laser‐induced fluorescence detection
Published in Electrophoresis (01-07-2021)“…In this work, we characterize a previously synthesized multi‐cationic aminopyrene‐based labeling tag for oligosaccharide analysis by capillary electrophoresis…”
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Synthesis and application of BODIPY-based fluorescent labeling tag for oligosaccharide and N-linked glycan analysis by high-performance liquid chromatography with fluorescence detection
Published in Analytica chimica acta (02-01-2024)“…Glycosylation analysis is still challenging, not only because of the extreme structure complexity and conjugation diversity of glycans but also because of…”
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Multi-charged labeling of oligosaccharides and N-linked glycans by hexahistidine-based tags for capillary electrophoresis-mass spectrometry analysis
Published in Journal of Chromatography A (27-07-2018)“…•Derivatization of saccharides by hexahistidine tags was investigated.•Labeling reactions were performed by reductive amination and hydrazone…”
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Multi-cationic aminopyrene-based labeling tags for oligosaccharide analysis by capillary electrophoresis-mass spectrometry
Published in Analytica chimica acta (25-01-2020)“…In this work, new multi-cationic aminopyrene-based labeling tags were designed and synthesized for oligosaccharide analysis by capillary electrophoresis-mass…”
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Structural analysis and differentiation of reducing and nonreducing neutral model starch oligosaccharides by negative-ion electrospray ionization ion-trap mass spectrometry
Published in International journal of mass spectrometry (15-03-2010)“…The identification of nonreducing saccharides, as well as the differentiation between α-(1 → 4) and α-(1 → 6) linkage were obtained on the basis of presence of…”
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Journal Article -
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Investigation of a side reaction occurring during N-linked glycan labeling by cationic tags
Published in Journal of Chromatography A (05-10-2018)“…•Positively labeled oligosaccharides and N-linked glycans were analyzed by CE-MS.•Several different labeling strategies were tested with different cationic…”
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Investigation of a side reaction occurring during -linked glycan labeling by cationic tags
Published in Journal of Chromatography A (01-10-2018)Get full text
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Separation of labeled isomeric oligosaccharides by hydrophilic interaction liquid chromatography – the role of organic solvent in manipulating separation selectivity of the amide stationary phase
Published in Journal of Chromatography A (16-08-2021)“…•HILIC separation of labeled isomeric oligosaccharides.•Increasing selectivity with alternative solvents.•Comparison for a representative set of labels and…”
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