Search Results - "Clutterbuck, Elizabeth A."

AS03- and MF59-Adjuvanted Influenza Vaccines in Children by Wilkins, Amanda L, Kazmin, Dmitri, Napolitani, Giorgio, Clutterbuck, Elizabeth A, Pulendran, Bali, Siegrist, Claire-Anne, Pollard, Andrew J

“…Influenza is a major cause of respiratory disease leading to hospitalization in young children. However, seasonal trivalent influenza vaccines (TIVs) have been…”
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Pneumococcal Conjugate and Plain Polysaccharide Vaccines Have Divergent Effects on Antigen-Specific B Cells by Clutterbuck, Elizabeth A., Lazarus, Rajeka, Yu, Ly-Mee, Bowman, Jaclyn, Bateman, Elizabeth A. L., Diggle, Linda, Angus, Brian, Peto, Tim E., Beverley, Peter C., Mant, David, Pollard, Andrew J.

“…Background. A 23-valent unconjugated pneumococcal polysaccharide vaccine (23vP), routinely administered at the age of 65, has limited effectiveness, and…”
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Design, recruitment, and microbiological considerations in human challenge studies by Darton, Thomas C, DPhil, Blohmke, Christoph J, Dr, Moorthy, Vasee S, DPhil, Altmann, Daniel M, Prof, Hayden, Frederick G, Prof, Clutterbuck, Elizabeth A, PhD, Levine, Myron M, Prof, Hill, Adrian V S, Prof, Pollard, Andrew J, Prof

“…Summary Since the 18th century a wealth of knowledge regarding infectious disease pathogenesis, prevention, and treatment has been accumulated from findings of…”
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BCR repertoire sequencing: different patterns of B‐cell activation after two Meningococcal vaccines by Galson, Jacob D, Clutterbuck, Elizabeth A, Trück, Johannes, Ramasamy, Maheshi N, Münz, Márton, Fowler, Anna, Cerundolo, Vincenzo, Pollard, Andrew J, Lunter, Gerton, Kelly, Dominic F

“…Next‐generation sequencing was used to investigate the B‐cell receptor heavy chain transcript repertoire of different B‐cell subsets (naive, marginal zone…”
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Computational mining of B cell receptor repertoires reveals antigen-specific and convergent responses to Ebola vaccination by Richardson, Eve, Bibi, Sagida, McLean, Florence, Schimanski, Lisa, Rijal, Pramila, Ghraichy, Marie, von Niederhäusern, Valentin, Trück, Johannes, Clutterbuck, Elizabeth A, O'Connor, Daniel, Luhn, Kerstin, Townsend, Alain, Peters, Bjoern, Pollard, Andrew J, Deane, Charlotte M, Kelly, Dominic F

“…Outbreaks of Ebolaviruses, such as Sudanvirus (SUDV) in Uganda in 2022, demonstrate that species other than the Zaire ebolavirus (EBOV), which is currently the…”
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Analysis of B Cell Repertoire Dynamics Following Hepatitis B Vaccination in Humans, and Enrichment of Vaccine-specific Antibody Sequences by Galson, Jacob D., Trück, Johannes, Fowler, Anna, Clutterbuck, Elizabeth A., Münz, Márton, Cerundolo, Vincenzo, Reinhard, Claudia, van der Most, Robbert, Pollard, Andrew J., Lunter, Gerton, Kelly, Dominic F.

“…Generating a diverse B cell immunoglobulin repertoire is essential for protection against infection. The repertoire in humans can now be comprehensively…”
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Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries by Versteegen, Pauline, Barkoff, Alex-Mikael, Valente Pinto, Marta, van de Kasteele, Jan, Knuutila, Aapo, Bibi, Sagida, de Rond, Lia, Teräsjärvi, Johanna, Sanders, Katherine, de Zeeuw-Brouwer, Mary-Lène, Luoto, Raakel, Ten Hulscher, Hinke, Clutterbuck, Elizabeth A, Sanders, Elisabeth A M, Mertsola, Jussi, Berbers, Guy A M, He, Qiushui, Kelly, Dominic F, Buisman, Anne-Marie

“…Immunogenicity of acellular pertussis (aP) vaccines is conventionally assessed by measuring antibody responses but antibody concentrations wane quickly after…”
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No long-term evidence of hyporesponsiveness after use of pneumococcal conjugate vaccine in children previously immunized with pneumococcal polysaccharide vaccine by Licciardi, Paul V., PhD, Toh, Zheng Quan, BSc(Hons), Clutterbuck, Elizabeth A., PhD, Balloch, Anne, MSc, Marimla, Rachel A., BBiomed(Hons), Tikkanen, Leena, MSc, Lamb, Karen E., PhD, Bright, Kathryn J., BSN, Rabuatoka, Uraia, BMLSc, Tikoduadua, Lisi, MBBS, Boelsen, Laura K., BBiomedSc(Hons), Dunne, Eileen M., PhD, Satzke, Catherine, PhD, Cheung, Yin Bun, PhD, Pollard, Andrew J., PhD, Russell, Fiona M., PhD, Mulholland, Edward K., MD

“…Background A randomized controlled trial in Fiji examined the immunogenicity and effect on nasopharyngeal carriage after 0, 1, 2, or 3 doses of 7-valent…”
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Memory-like innate response to booster vaccination with MF-59 adjuvanted influenza vaccine in children by Kazmin, Dmitri, Clutterbuck, Elizabeth A., Napolitani, Giorgio, Wilkins, Amanda L., Tarlton, Andrea, Thompson, Amber J., Montomoli, Emmanuele, Lapini, Guilia, Bihari, Smiti, White, Rachel, Jones, Claire, Snape, Matthew D., Galal, Ushma, Yu, Ly-Mee, Rappuoli, Rino, Del Giudice, Giuseppe, Pollard, Andrew J., Pulendran, Bali

“…The pediatric population receives the majority of vaccines globally, yet there is a paucity of studies on the transcriptional response induced by immunization…”
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Evaluation of the induction of immune memory following infant immunisation with serogroup C Neisseria meningitidis conjugate vaccines--exploratory analyses within a randomised controlled trial by Khatami, Ameneh, Clutterbuck, Elizabeth A, Thompson, Amber J, McKenna, Jennifer A, Pace, David, Birks, Jacqueline, Snape, Matthew D, Pollard, Andrew J

“…We measured meningococcal serogroup C (MenC)-specific memory B-cell responses in infants by Enzyme-Linked Immunospot (ELISpot) following different MenC…”
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Kinetics of the Natural, Humoral Immune Response to Salmonella enterica Serovar Typhi in Kathmandu, Nepal by Pulickal, Anoop S, Gautam, Samir, Clutterbuck, Elizabeth A, Thorson, Stephen, Basynat, Buddha, Adhikari, Neelam, Makepeace, Katherine, Rijpkema, Sjoerd, Borrow, Ray, Farrar, Jeremy J, Pollard, Andrew J

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Serotype-Specific and Age-Dependent Generation of Pneumococcal Polysaccharide-Specific Memory B-Cell and Antibody Responses to Immunization with a Pneumococcal Conjugate Vaccine by Clutterbuck, Elizabeth A, Oh, Sarah, Hamaluba, Mainga, Westcar, Sharon, Beverley, Peter C L, Pollard, Andrew J

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial by Stuart, Arabella S V, Shaw, Robert H, Liu, Xinxue, Greenland, Melanie, Aley, Parvinder K, Andrews, Nick J, Cameron, J C, Charlton, Sue, Clutterbuck, Elizabeth A, Collins, Andrea M, Darton, Tom, Dinesh, Tanya, Duncan, Christopher J A, England, Anna, Faust, Saul N, Ferreira, Daniela M, Finn, Adam, Goodman, Anna L, Green, Christopher A, Hallis, Bassam, Heath, Paul T, Hill, Helen, Horsington, Bryn M, Lambe, Teresa, Lazarus, Rajeka, Libri, Vincenzo, Lillie, Patrick J, Mujadidi, Yama F, Payne, Ruth, Plested, Emma L, Provstgaard-Morys, Samuel, Ramasamy, Maheshi N, Ramsay, Mary, Read, Robert C, Robinson, Hannah, Screaton, Gavin R, Singh, Nisha, Turner, David P J, Turner, Paul J, Vichos, Iason, White, Rachel, Nguyen-Van-Tam, Jonathan S, Snape, Matthew D

“…Given the importance of flexible use of different COVID-19 vaccines within the same schedule to facilitate rapid deployment, we studied mixed priming schedules…”
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Safety and Immunogenicity of Novel Adenovirus Type 26– and Modified Vaccinia Ankara–Vectored Ebola Vaccines: A Randomized Clinical Trial by Milligan, Iain D, Gibani, Malick M, Sewell, Richard, Clutterbuck, Elizabeth A, Campbell, Danielle, Plested, Emma, Nuthall, Elizabeth, Voysey, Merryn, Silva-Reyes, Laura, McElrath, M. Juliana, De Rosa, Stephen C, Frahm, Nicole, Cohen, Kristen W, Shukarev, Georgi, Orzabal, Nicola, van Duijnhoven, Wilbert, Truyers, Carla, Bachmayer, Nora, Splinter, Daniel, Samy, Nathaly, Pau, Maria Grazia, Schuitemaker, Hanneke, Luhn, Kerstin, Callendret, Benoit, Van Hoof, Johan, Douoguih, Macaya, Ewer, Katie, Angus, Brian, Pollard, Andrew J, Snape, Matthew D

“…IMPORTANCE: Developing effective vaccines against Ebola virus is a global priority. OBJECTIVE: To evaluate an adenovirus type 26 vector vaccine encoding Ebola…”
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The seroepidemiology of Haemophilus influenzae type b prior to introduction of an immunization programme in Kathmandu, Nepal by Marshall, Andrew S J, Barker, Charlotte I S, Pulickal, Anoop S, Kibwana, Elizabeth, Gautam, Samir C, Clutterbuck, Elizabeth A, Thorson, Stephen M, Shrestha, Shrijana, Adhikari, Neelam, Pollard, Andrew J, Kelly, Dominic F

“…Haemophilus influenzae type b (Hib) is now recognized as an important pathogen in Asia. To evaluate disease susceptibility, and as a marker of Hib transmission…”
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Antibody-Dependent Natural Killer Cell Activation After Ebola Vaccination by Wagstaffe, Helen R, Clutterbuck, Elizabeth A, Bockstal, Viki, Stoop, Jeroen N, Luhn, Kerstin, Douoguih, Macaya, Shukarev, Georgi, Snape, Matthew D, Pollard, Andrew J, Riley, Eleanor M, Goodier, Martin R

“…Abstract Background Antibody Fc-mediated functions, such as antibody-dependent cellular cytotoxicity, contribute to vaccine-induced protection against viral…”
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Ebola virus glycoprotein stimulates IL-18-dependent natural killer cell responses by Wagstaffe, Helen R, Clutterbuck, Elizabeth A, Bockstal, Viki, Stoop, Jeroen N, Luhn, Kerstin, Douoguih, Macaya, Shukarev, Georgi, Snape, Matthew D, Pollard, Andrew J, Riley, Eleanor M, Goodier, Martin R

“…BACKGROUNDNK cells are activated by innate cytokines and viral ligands to kill virus-infected cells. These functions are enhanced during secondary immune…”
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B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation by Galson, Jacob D, Trück, Johannes, Clutterbuck, Elizabeth A, Fowler, Anna, Cerundolo, Vincenzo, Pollard, Andrew J, Lunter, Gerton, Kelly, Dominic F

“…A diverse B-cell repertoire is essential for recognition and response to infectious and vaccine antigens. High-throughput sequencing of B-cell receptor (BCR)…”
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Persistence of the immune response after two doses of ChAdOx1 nCov-19 (AZD1222): 1 year of follow-up of two randomized controlled trials by Voysey, Merryn, Flaxman, Amy, Aboagye, Jeremy, Aley, Parvinder K, Belij-Rammerstorfer, Sandra, Bibi, Sagida, Bittaye, Mustapha, Cappuccini, Federica, Charlton, Sue, Clutterbuck, Elizabeth A, Davies, Sophie, Dold, Christina, Edwards, Nick J, Ewer, Katie J, Faust, Saul N, Folegatti, Pedro M, Fowler, Jamie, Gilbride, Ciaran, Gilbert, Sarah C, Godfrey, Leila, Hallis, Bassam, Humphries, Holly E, Jenkin, Daniel, Kerridge, Simon, Mujadidi, Yama F, Plested, Emma, Ramasamy, Maheshi N, Robinson, Hannah, Sanders, Helen, Snape, Matthew D, Song, Rinn, Thomas, Kelly M, Ulaszewska, Marta, Woods, Danielle, Wright, Daniel, Pollard, Andrew J, Lambe, Teresa

“…Abstract The trajectory of immune responses following the primary dose series determines the decline in vaccine effectiveness over time. Here we report on…”
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Reactogenicity, immunogenicity and breakthrough infections following heterologous or fractional second dose COVID-19 vaccination in adolescents (Com-COV3): A randomised controlled trial by Kelly, Eimear, Greenland, Melanie, de Whalley, Philip C.S., Aley, Parvinder K., Plested, Emma L., Singh, Nisha, Koleva, Stanislava, Tonner, Sharon, Macaulay, Grace C., Read, Robert C., Ramsay, Mary, Cameron, J.Claire, Turner, David P.J., Heath, Paul T., Bernatoniene, Jolanta, Connor, Philip, Cathie, Katrina, Faust, Saul N., Banerjee, Indraneel, Cantrell, Liberty, Mujadidi, Yama F., Belhadef, Hanane Trari, Clutterbuck, Elizabeth A., Anslow, Rachel, Valliji, Zara, James, Tim, Hallis, Bassam, Otter, Ashley David, Lambe, Teresa, Nguyen-Van-Tam, Jonathan S., Minassian, Angela M., Liu, Xinxue, Snape, Matthew D.

“…This was the first study to investigate the reactogenicity and immunogenicity of heterologous or fractional second dose COVID-19 vaccine regimens in…”
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