Search Results - "Clinton, Timothy"

Defining Resistance to Immune Checkpoint Inhibitors in Urothelial Carcinoma: Insights from PURE-01 by Clinton, Timothy N.

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Validating the predictors of outcomes after radical cystectomy for bladder cancer by Woldu, Solomon L., Sanli, Oner, Clinton, Timothy N., Lotan, Yair

“…Background An assessment of surgical risk is essential for patient counseling and decision making, and it can provide rationale adjustment for patient…”
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Impact of hospital case volume on testicular cancer outcomes and practice patterns by Woldu, Solomon L., Matulay, Justin T., Clinton, Timothy N., Singla, Nirmish, Krabbe, Laura-Maria, Hutchinson, Ryan C., Sagalowsky, Arthur, Lotan, Yair, Margulis, Vitaly, Bagrodia, Aditya

“…Given the rarity of testicular germ cell tumors (TGCTs) and the complex aspects of management, we evaluate the effect of hospital TGCT case volume on overall…”
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The use of blue light flexible cystoscopy with hexaminolevulinate & the diagnosis of bladder cancer by Clinton, Timothy N, Lotan, Yair

“…Blue light cystoscopy improves the detection of bladder cancer at time of transurethral resection of bladder tumor for nonmuscle-invasive bladder cancer. This…”
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Discordance between Ureteroscopic Biopsy and Final Pathology for Upper Tract Urothelial Carcinoma by Margolin, Ezra J., Matulay, Justin T., Li, Gen, Meng, Xiaosong, Chao, Brian, Vijay, Varun, Silver, Hayley, Clinton, Timothy N., Krabbe, Laura-Maria, Woldu, Solomon L., Singla, Nirmish, Bagrodia, Aditya, Margulis, Vitaly, Huang, William C., Bjurlin, Marc A., Shah, Ojas, Anderson, Christopher B.

“…We evaluated the discordance between ureteroscopic biopsy and surgical pathology findings for grading and staging upper tract urothelial carcinoma. We also…”
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Preoperative multiplex nomogram for prediction of high-risk nonorgan-confined upper-tract urothelial carcinoma by Petros, Firas G., Qiao, Wei, Singla, Nirmish, Clinton, Timothy N., Robyak, Haley, Raman, Jay D., Margulis, Vitaly, Matin, Surena F.

“…•Development and validation of an accurate nomogram for the prediction of locally advanced nonorgan-confined (NOC) UTUC was undertaken using 24 multiplex…”
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Degarelix versus luteinizing hormone-releasing hormone agonists for the treatment of prostate cancer by Clinton, Timothy N, Woldu, Solomon L, Raj, Ganesh V

“…Androgen deprivation therapy (ADT) is the mainstay for advanced, hormone-sensitive prostate cancer, and options include surgical castration, luteinizing…”
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Total Margin Control Is Superior to Traditional Margin Assessment for Treatment of Low-Stage Penile Squamous Cell Carcinoma by O'Connell, Katie A, Thomas, Jacob L, Murad, Fadi, Zhou, Guohai, Sonpavde, Guru P, Mossanen, Matthew, Clinton, Timothy N, Ji-Xu, Antonio, Alton, Kristina, Spiess, Philippe E, Rossi, Anthony M, Schmults, Chrysalyne D

“…Penile cancer is rare, with significant morbidity and limited literature assessing utility of peripheral and deep en face margin assessment (PDEMA) vs…”
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Impact of DNA Repair Deficiency in the Evolving Treatment Landscape of Bladder Cancer by D’Andrea, Vincent D., Magnani, Christopher J., Ernandez, John, Bellmunt, Joaquim, Mossanen, Matthew, Clinton, Timothy N., Carvalho, Filipe L. F., Mouw, Kent W.

“…Purpose of review This review explores the current landscape of treatments which target the DNA damage response (DDR) in metastatic and muscle-invasive bladder…”
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Factors predictive of recurrence, metastasis and death in node-negative penile squamous cell carcinoma: A retrospective multicentre cohort study by O'Connell, Katie A, Thomas, Jacob L, Murad, Fadi, Zhou, Guohai, Sonpavde, Guru P, Mossanen, Matthew, Clinton, Timothy N, Ji-Xu, Antonio, Spiess, Philippe E, Rossi, Anthony M, Schmults, Chrysalyne D

“…Penile squamous cell carcinoma (PSCC) carries significant morbidity and mortality. Literature is limited regarding prognostic factors, especially prognostic…”
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Genomic heterogeneity as a barrier to precision oncology in urothelial cancer by Clinton, Timothy N., Chen, Ziyu, Wise, Hannah, Lenis, Andrew T., Chavan, Shweta, Donoghue, Mark T.A., Almassi, Nima, Chu, Carissa E., Dason, Shawn, Rao, Pavitra, Rodrigues, James A., Vasani, Naresh B., Ridouani, Fourat, Rosenberg, Jonathan E., Bajorin, Dean F., Teo, Min Yuen, Bochner, Bernard H., Berger, Michael F., Ostrovnaya, Irina, Pietzak, Eugene J., Iyer, Gopa, Gao, Sizhi Paul, Hu, Wenhuo, Al-Ahmadie, Hikmat A., Solit, David B.

“…Precision oncology relies on the accurate molecular characterization of individual patients with cancer at the time of treatment initiation. However, tumor…”
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Therapeutic strategies for upper tract urothelial carcinoma by Freifeld, Yuval, Krabbe, Laura-Maria, Clinton, Timothy N., Woldu, Solomon L., Margulis, Vitaly

“…Introduction: Many controversies exist regarding the appropriate management of patients with upper tract urothelial carcinoma (UTUC), including staging,…”
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Molecular Heterogeneity and Immune Infiltration Drive Clinical Outcomes in Upper Tract Urothelial Carcinoma by Kim, Kwanghee, Alam, Syed M., Kuo, Fengshen, Chen, Ziyu, Yip, Wesley, Katims, Andrew B., Chu, Carissa, Lenis, Andrew T., Hu, Wenhuo, Gokturk Ozcan, Gamze, Chen, Jie-Fu, Firouzi, Sanaz, Elhanati, Yuval, Clinton, Timothy N., Aulitzky, Andreas, Almassi, Nima, Fujii, Yoich, Tracey, Andrew T., Reisz, Peter A., Budhu, Sadna, Vuong, Lynda, Eichholz, Jordan, Woo, Hyung Jun, Nogueira, Lucas, Gao, Sizhi P., Scherz, Avigdor, Aggen, David H., Rosenberg, Jonathan E., Pietzak, Eugene J., Seshan, Venkatraman, Greenbaum, Benjamin, Becker, Anton, Akin, Oguz, Iyer, Gopa, Al-Ahmadie, Hikmat, Hakimi, A. Ari, Merghoub, Taha, Solit, David B., Coleman, Jonathan A.

“…RNA sequencing of upper tract urothelial cancer (UTUC) identifies previously underappreciated molecular heterogeneity and suggests that patients with UTUC who…”
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Is there an oncological benefit to extended lymphadenectomy for muscle-invasive bladder cancer? by Clinton, Timothy N, Huang, Chun, Goh, Alvin C

“…The full optimal extent of a pelvic lymph node dissection (PLND) at time of radical cystectomy (RC) has not yet been determined. The diagnostic role of LND is…”
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Anticoagulation prophylaxis patterns following retroperitoneal lymph node dissection for testis cancer by D'Andrea, Vincent, Jason Qian, Zhiyu, Yim, Kendrick, Egan, Jillian, Magnani, Christopher J, Feldman, Adam, Salari, Keyan, Tewari, Alok, Steele, Graeme, Mossanen, Matthew, Preston, Mark, Chang, Steven L, Clinton, Timothy N

“…Retroperitoneal lymph node dissection (RPLND) is the standard of care for testicular cancer in various disease settings. Deep vein thrombosis (DVT)…”
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Smoking characteristics and years since quitting smoking of US adults diagnosed with lung and bladder cancer: A national health and nutrition examination survey analysis by Beatrici, Edoardo, Labban, Muhieddine, Filipas, Dejan K, Stone, Benjamin V, Reis, Leonardo O, Dagnino, Filippo, Lughezzani, Giovanni, Buffi, Nicolò M, Lipsitz, Stuart R, Clinton, Timothy N, Matulewicz, Richard S, Trinh, Quoc-Dien, Cole, Alexander P

“…Smoking is a recognized risk factor for bladder BC and lung cancer LC. We investigated the enduring risk of BC after smoking cessation using U.S. national…”
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Sequential intravesical gemcitabine/docetaxel provides a durable remission in recurrent high-risk NMIBC following BCG therapy by Yim, Kendrick, Melnick, Kevin, Mott, Sarah L, Carvalho, Filipe L F, Zafar, Affan, Clinton, Timothy N, Mossanen, Matthew, Steele, Graeme S, Hirsch, Michelle, Rizzo, Natalie, Wu, Chin-Lee, Mouw, Kent W, Wszolek, Matthew, Salari, Keyan, Feldman, Adam, Kibel, Adam S, O'Donnell, Michael A, Preston, Mark A

“…Bacillus Calmette-Guerin (BCG) is the standard of care for high-risk nonmuscle invasive bladder cancer (NMIBC), but half of patients develop disease…”
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Pathologic stage as a surrogate for oncologic outcomes after receipt of neoadjuvant chemotherapy for high-grade upper tract urothelial carcinoma by Singla, Nirmish, Christie, Alana, Freifeld, Yuval, Ghandour, Rashed A., Woldu, Solomon L., Clinton, Timothy N., Petros, Firas G., Robyak, Haley, Yeh, Hsin-Chih, Fang, Dong, Enikeev, Dmitry, Bagrodia, Aditya, Sagalowsky, Arthur I., Lotan, Yair, Raman, Jay D., Matin, Surena F., Margulis, Vitaly

“…•Upper tract urothelial carcinoma patients who achieve ypT0-1 after neoadjuvant chemotherapy exhibit outcomes that behave as well as those inherently…”
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Urinary Diversion Disparity Following Radical Cystectomy for Bladder Cancer in the Hispanic Population by Rios, Emily M., Parma, Mitchell A., Fernandez, Roman A., Clinton, Timothy N., Reyes, Ryan M., Kaushik, Dharam, Pruthi, Deepak, Mansour, Ahmed M., Mukherjee, Neelam, Gelfond, Jon, Wheeler, Karen M., Svatek, Robert S.

“…To determine if disparities in quality of surgical care exist between Hispanics and non-Hispanics undergoing radical cystectomy for bladder cancer. An…”
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Review of the Clinical Approaches to the Use of Urine-based Tumor Markers in Bladder Cancer by Clinton, Timothy, Lotan, Yair

“…Bladder cancer is a common disease with a stable incidence for the past few decades despite advancements in molecular and genetic determinants of cancer…”
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