Search Results - "Clinical immunology (Orlando, Fla.)"

The efficacy of PD-1/PD-L1 blockade in cold cancers and future perspectives by Majidpoor, Jamal, Mortezaee, Keywan

“…Colorectal cancer (CRC), and breast, ovarian, pancreatic and prostate cancers are generally considered as low immune-reactive cancers that represent either…”
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Recent advances on signaling pathways and their inhibitors in rheumatoid arthritis by Liu, Shuang, Ma, Hongxing, Zhang, Huaxi, Deng, Chengjie, Xin, Ping

“…Rheumatoid arthritis (RA) is characterized by systemic synovitis leading to joint destruction in which imbalances in pro-inflammatory and anti-inflammatory…”
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Characterization of PANoptosis patterns predicts survival and immunotherapy response in gastric cancer by Pan, Hongda, Pan, Jingxin, Li, Pei, Gao, Jianpeng

“…Accumulating evidence suggests that pyroptosis, apoptosis and necroptosis are deeply involved in cancer immunity. However, the role of PANoptosis in gastric…”
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Immune–microbiota interactions in health and disease by Palm, Noah W, de Zoete, Marcel R, Flavell, Richard A

“…Abstract Recent studies have revealed that the intestinal microbiota plays an important role in host physiology and pathophysiology in health and disease. One…”
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Juvenile-onset systemic lupus erythematosus: Update on clinical presentation, pathophysiology and treatment options by Smith, Eve Mary Dorothy, Lythgoe, Hanna, Midgley, Angela, Beresford, Michael William, Hedrich, Christian Michael

“…Juvenile-onset systemic lupus erythematosus (jSLE) accounts for up to 20% of all SLE patients. Key differences between juvenile- and adult-onset (aSLE) disease…”
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Therapy of type 1 diabetes with CD4(+)CD25(high)CD127-regulatory T cells prolongs survival of pancreatic islets - results of one year follow-up by Marek-Trzonkowska, Natalia, Myśliwiec, Małgorzata, Dobyszuk, Anita, Grabowska, Marcelina, Derkowska, Ilona, Juścińska, Jolanta, Owczuk, Radosław, Szadkowska, Agnieszka, Witkowski, Piotr, Młynarski, Wojciech, Jarosz-Chobot, Przemysława, Bossowski, Artur, Siebert, Janusz, Trzonkowski, Piotr

“…It is hypothesized that CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) can prevent destruction of pancreatic islets protecting from type 1 diabetes (DM1)…”
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Sjogren's syndrome: Clinical aspects by Vivino, Frederick B

“…Abstract Sjogren's syndrome (SS) is the 2nd most common chronic autoimmune rheumatic disease and associated with a high burden of illness. Morbidity arises not…”
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Comorbidities associated with psoriatic arthritis: Review and update by Perez-Chada, Lourdes M., Merola, Joseph F.

“…Psoriatic arthritis is an inflammatory arthropathy frequently associated with psoriasis and several other comorbidities. The goal of this review is to…”
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COVID-19 pathophysiology: A review by Yuki, Koichi, Fujiogi, Miho, Koutsogiannaki, Sophia

“…In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of acute atypical respiratory diseases in Wuhan, Hubei Province, China. The…”
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The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China by Zhang, Wen, Zhao, Yan, Zhang, Fengchun, Wang, Qian, Li, Taisheng, Liu, Zhengyin, Wang, Jinglan, Qin, Yan, Zhang, Xuan, Yan, Xiaowei, Zeng, Xiaofeng, Zhang, Shuyang

“…The pandemic outbreak of coronavirus disease 2019 (COVID-19) is rapidly spreading all over the world. Reports from China showed that about 20% of patients…”
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Programmed death-1 pathway in cancer and autoimmunity by Pedoeem, Ariel, Azoulay-Alfaguter, Inbar, Strazza, Marianne, Silverman, Gregg J, Mor, Adam

“…Abstract Programmed death-1 (PD-1) is a co-receptor that is expressed predominantly by T cells. The binding of PD-1 to its ligands, PD-L1 or PD-L2, is vital…”
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Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis by Alli, Abdel A., Desai, Dhruv, Elshika, Ahmed, Conrad, Marcus, Proneth, Bettina, Clapp, William, Atkinson, Carl, Segal, Mark, Searcy, Louis A., Denslow, Nancy D., Bolisetty, Subhashini, Mehrad, Borna, Morel, Laurence, Scindia, Yogesh

“…Ferroptosis is a druggable, iron-dependent form of cell death that is characterized by lipid peroxidation but has received little attention in lupus nephritis…”
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Laboratory biomarkers associated with COVID-19 severity and management by Keddie, S., Ziff, O., Chou, M.K.L., Taylor, R.L., Heslegrave, A., Garr, E., Lakdawala, N., Church, A., Ludwig, D., Manson, J., Scully, M., Nastouli, E., Chapman, M.D., Hart, M., Lunn, M.P.

“…The heterogeneous disease course of COVID-19 is unpredictable, ranging from mild self-limiting symptoms to cytokine storms, acute respiratory distress syndrome…”
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Lupus Nephritis Biomarkers by Soliman, Samar, Mohan, Chandra

“…Abstract Lupus nephritis (LN), a potentially destructive outcome of SLE, is a real challenge in the management of SLE because of the difficulty in diagnosing…”
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Hydroxychloroquine inhibiting neutrophil extracellular trap formation alleviates hepatic ischemia/reperfusion injury by blocking TLR9 in mice by Zhang, Sigong, Zhang, Qiuyue, Wang, Furong, Guo, Xuehui, Liu, Tao, Zhao, Yang, Gu, Baohong, Chen, Hao, Li, Yumin

“…Hepatic ischemia/reperfusion (I/R) injury may arise after partial hepatectomy and liver transplantation. Neutrophil extracellular traps (NETs) were involved in…”
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The microbiota and autoimmunity: Their role in thyroid autoimmune diseases by Köhling, Hedda L., Plummer, Sue F., Marchesi, Julian R., Davidge, Kelly S., Ludgate, Marian

“…Since the 1970s, the role of infectious diseases in the pathogenesis of Graves' disease (GD) has been an object of intensive research. The last decade has…”
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COVID-19: Immunology and treatment options by Felsenstein, Susanna, Herbert, Jenny A., McNamara, Paul S., Hedrich, Christian M.

“…The novel coronavirus SARS-CoV2 causes COVID-19, a pandemic threatening millions. As protective immunity does not exist in humans and the virus is capable of…”
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Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases by Vojdani, Aristo, Kharrazian, Datis

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Autophagy and autoimmunity by Wu, Dennis J, Adamopoulos, Iannis E

“…Abstract Autophagy is a highly conserved protein degradation pathway from yeasts to humans that is essential for removing protein aggregates and misfolded…”
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Exosomes as nanocarriers for immunotherapy of cancer and inflammatory diseases by Tran, Thanh-Huyen, Mattheolabakis, George, Aldawsari, Hibah, Amiji, Mansoor

“…Abstract Cell secreted exosomes (30–100 nm vesicles) play a major role in intercellular communication due to their ability to transfer proteins and nucleic…”
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