Search Results - "Clinical and experimental rheumatology"

COVID-19, cytokines and immunosuppression: what can we learn from severe acute respiratory syndrome? by Sarzi-Puttini, Piercarlo, Giorgi, Valeria, Sirotti, Silvia, Marotto, Daniela, Ardizzone, Sandro, Rizzardini, Giuliano, Antinori, Spinello, Galli, Massimo

“…A severe outbreak of coronavirus disease 2019 (COVID-19) emerged in China in December 2019, and spread so rapidly that more than 200,000 cases have so far been…”
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Osteoarthritis is a serious disease by Hawker, Gillian A

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Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in patients with severe COVID-19 by Sciascia, Savino, Aprà, Franco, Baffa, Alessandra, Baldovino, Simone, Boaro, Daniela, Boero, Roberto, Bonora, Stefano, Calcagno, Andrea, Cecchi, Irene, Cinnirella, Giacoma, Converso, Marcella, Cozzi, Martina, Crosasso, Paola, De Iaco, Fabio, Di Perri, Giovanni, Eandi, Mario, Fenoglio, Roberta, Giusti, Massimo, Imperiale, Daniele, Imperiale, Gianlorenzo, Livigni, Sergio, Manno, Emilpaolo, Massara, Carlo, Milone, Valeria, Natale, Giuseppe, Navarra, Mauro, Oddone, Valentina, Osella, Sara, Piccioni, Pavilio, Radin, Massimo, Roccatello, Dario, Rossi, Daniela

“…No agent has yet been proven to be effective for the treatment of patients with severe COVID-19. We conducted a pilot prospective open, single-arm multicentre…”
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One year in review 2019: pathogenesis of rheumatoid arthritis by Croia, Cristina, Bursi, Roberto, Sutera, Donatella, Petrelli, Fiorella, Alunno, Alessia, Puxeddu, Ilaria

“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease influenced by both genetic and environmental factors. Over the last few years,…”
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One year in review 2020: pathogenesis of rheumatoid arthritis by Giannini, Daiana, Antonucci, Matteo, Petrelli, Fiorella, Bilia, Silvia, Alunno, Alessia, Puxeddu, Ilaria

“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease influenced by both genetic, epigenetic and environmental factors. The discovery of new…”
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The mechanism of action of tofacitinib - an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis by Hodge, Jennifer A, Kawabata, Thomas T, Krishnaswami, Sriram, Clark, James D, Telliez, Jean-Baptiste, Dowty, Martin E, Menon, Sujatha, Lamba, Manisha, Zwillich, Samuel

“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterised by infiltration of immune cells into the affected synovium, release of…”
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Innate inflammation and synovial macrophages in osteoarthritis pathophysiology by Griffin, Timothy M, Scanzello, Carla R

“…Although osteoarthritis (OA) was historically referred to as the non-inflammatory arthritis, it is now considered a condition involving persistent low-grade…”
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COVID-19: the new challenge for rheumatologists by Ferro, Francesco, Elefante, Elena, Baldini, Chiara, Bartoloni, Elena, Puxeddu, Ilaria, Talarico, Rosaria, Mosca, Marta, Bombardieri, Stefano

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The function of microRNAs in cartilage and osteoarthritis by Swingler, Tracey E, Niu, Lingzi, Smith, Perry, Paddy, Paige, Le, Linh, Barter, Matthew J, Young, David A, Clark, Ian M

“…MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression and have been shown to have key roles in both chondrocyte development and…”
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One year in review 2022: systemic lupus erythematosus by Zucchi, Dina, Elefante, Elena, Schilirò, Davide, Signorini, Viola, Trentin, Francesca, Bortoluzzi, Alessandra, Tani, Chiara

“…Systemic lupus erythematosus (SLE) is a chronic multisystem auto-immune disease with extremely varied clinical manifestations and a complex pathogenesis. New…”
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The Disease Activity Score (DAS) and the Disease Activity Score using 28 joint counts (DAS28) in the management of rheumatoid arthritis by van Riel, Piet L C M, Renskers, Lisanne

“…In rheumatoid arthritis (RA), disease activity cannot be measured in all individual patients according to a single variable. The Disease Activity Score (DAS)…”
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How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: analysis of 10,500 patients (Sjögren Big Data Project) by Brito-Zerón, Pilar, Acar-Denizli, Nihan, Ng, Wan-Fai, Zeher, Margit, Rasmussen, Astrid, Mandl, Thomas, Seror, Raphaele, Li, Xiaomei, Baldini, Chiara, Gottenberg, Jacques-Eric, Danda, Debashish, Quartuccio, Luca, Priori, Roberta, Hernandez-Molina, Gabriela, Armagan, Berkan, Kruize, Aike A, Kwok, Seung-Ki, Kvarnström, Marika, Praprotnik, Sonja, Sène, Damien, Bartoloni, Elena, Solans, Roser, Rischmueller, Maureen, Suzuki, Yasunori, Isenberg, David A, Valim, Valeria, Wiland, Piotr, Nordmark, Gunnel, Fraile, Guadalupe, Bootsma, Hendrika, Nakamura, Takashi, Giacomelli, Roberto, Devauchelle-Pensec, Valerie, Knopf, Andreas, Bombardieri, Michele, Trevisani, Virginia-Fernandes, Hammenfors, Daniel, Pasoto, Sandra G, Retamozo, Soledad, Gheita, Tamer A, Atzeni, Fabiola, Morel, Jacques, Vollenveider, Cristina, Horvath, Ildiko-Fanny, Sivils, Kathy L, Olsson, Peter, De Vita, Salvatore, Sánchez-Guerrero, Jorge, Kilic, Levent, Wahren-Herlenius, Marie, Mariette, Xavier, Ramos-Casals, Manuel

“…To evaluate the influence of the main immunological markers on the disease phenotype at diagnosis in a large international cohort of patients with primary…”
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Phenotypes of osteoarthritis: current state and future implications by Deveza, Leticia A, Nelson, Amanda E, Loeser, Richard F

“…In the most recent years, an extraordinary research effort has emerged to disentangle osteoarthritis heterogeneity, opening new avenues for progressing with…”
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One year in review 2018: pathogenesis of rheumatoid arthritis by Calabresi, Emanuele, Petrelli, Fiorella, Bonifacio, Angelo Francesco, Puxeddu, Ilaria, Alunno, Alessia

“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily affects joints. The several mechanisms involved in the development of the…”
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One year in review 2017: pathogenesis of rheumatoid arthritis by Angelotti, Francesca, Parma, Alice, Cafaro, Giacomo, Capecchi, Riccardo, Alunno, Alessia, Puxeddu, Ilaria

“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease influenced by both genetic and environmental factors. It has been postulated that a…”
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Use of Janus kinase inhibitors in dermatomyositis: a systematic literature review by Paik, Julie J, Lubin, Greg, Gromatzky, Austin, Mudd, Jr, Paul N, Ponda, Manish P, Christopher-Stine, Lisa

“…Dermatomyositis (DM) is an idiopathic inflammatory myopathy that commonly manifests with proximal muscle weakness and is associated with extramuscular…”
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Danger signals and inflammaging in osteoarthritis by Millerand, Marion, Berenbaum, Francis, Jacques, Claire

“…Osteoarthritis (OA) is the most common age-related chronic and disabling joint disease. Long considered to be a "wear and tear" disease, OA is now seen as a…”
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Autophagy, NLRP3 inflammasome and auto-inflammatory/immune diseases by Zhong, Zhenyu, Sanchez-Lopez, Elsa, Karin, Michael

“…Loss of homeostasis, as a result of pathogen invasion or self imbalance, causes tissue damage and inflammation. In addition to its well-established role in…”
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Physical therapy for patients with knee and hip osteoarthritis: supervised, active treatment is current best practice by Skou, Søren T, Roos, Ewa M

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Sjögren's syndrome: one year in review 2022 by Manfrè, Valeria, Chatzis, Loukas G, Cafaro, Giacomo, Fonzetti, Silvia, Calvacchi, Santina, Fulvio, Giovanni, Navarro Garcia, Inmaculada Conception, La Rocca, Gaetano, Ferro, Francesco, Perricone, Carlo, Bartoloni, Elena, Baldini, Chiara

“…Primary Sjögren's syndrome (pSS) is a complex disabling systemic autoimmune disorder. The hallmark of pSS is the T-cell-mediated hyperactivation of B-cells,…”
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