Diffuse pigmented villonodular synovitis: preliminary results with intralesional resection and p32 synoviorthesis

Because of the high local recurrence rate associated with surgical resection alone, patients with diffuse intraarticular pigmented villonodular synovitis were treated with surgical resection followed by colloidal chromic P32 synoviorthesis. The medical records of nine consecutive patients treated in...

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Bibliographic Details
Published in:	Clinical orthopaedics and related research Vol. 454; p. 186
Main Authors:	Ward, Sr, William G, Boles, Carol A, Ball, James D, Cline, Matthew T
Format:	Journal Article
Language:	English
Published:	United States 01-01-2007
Subjects:	Adolescent Adult Arthroscopy - methods Child Colloids Combined Modality Therapy Female Humans Injections, Intra-Articular Magnetic Resonance Imaging Male Middle Aged Orthopedic Procedures - methods Phosphorus Radioisotopes - administration & dosage Phosphorus Radioisotopes - pharmacology Phosphorus Radioisotopes - therapeutic use Recurrence Retrospective Studies Synovectomy Synovial Membrane - pathology Synovial Membrane - radiation effects Synovitis, Pigmented Villonodular - pathology Synovitis, Pigmented Villonodular - radiotherapy Synovitis, Pigmented Villonodular - surgery Treatment Outcome
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Summary:	Because of the high local recurrence rate associated with surgical resection alone, patients with diffuse intraarticular pigmented villonodular synovitis were treated with surgical resection followed by colloidal chromic P32 synoviorthesis. The medical records of nine consecutive patients treated in this manner were reviewed retrospectively to determine the recurrence rate of pigmented villonodular synovitis. All patients had either one or two surgical resections (arthroscopy in one patient, open resection in seven, arthroscopy and open resection in one). The involved joints included six knees and one each, ankle, elbow, and hip. Eight of the nine patients remained recurrence free at a mean followup of 38 months (range, 19-60 months) after surgery. One patient had a suspected asymptomatic recurrence documented by magnetic resonance imaging 29 months after surgery. Seven patients reported their normal activities as unrestricted. Five reported improved activity levels, one reported the activity level remained the same, and one reported activity as the same or better. None reported reduced activity levels. In these patients synoviorthesis with colloidal chromic P32 following gross resection of all obvious pigmented villonodular synovitis provided local disease control in all but one.
ISSN:	0009-921X
DOI:	10.1097/01.blo.0000229345.57092.a2