Search Results - "Cline, J.M."

17-β Estradiol reduces atherosclerosis without exacerbating lupus in ovariectomized systemic lupus erythematosus-susceptible LDLr−/− mice by Shelton, K.A, Cline, J.M, Cann, J.A

“…Abstract Objective To test the hypothesis that estrogen treatment in a radiation chimera mouse model of systemic lupus erythematosus (SLE) and atherosclerosis…”
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Progestin Treatment Induces Apoptosis and Modulates Transforming Growth Factor-β in the Uterine Endometrium by RODRIGUEZ, Gustavo C, RIMEL, B. J, WATKIN, William, TURBOV, Jane M, BARRY, Cathy, HONGYAN DU, MAXWELL, George L, CLINE, J. M

“…Background: Epidemiologic, animal, and human data suggest that progestins are potent endometrial cancer preventive agents. In the ovarian surface epithelium,…”
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Effects of tibolone and conventional HRT on the expression of estrogen and progesterone receptors in the breast by Ma, L, Hofling, M, Masironi, B, von Schoultz, B, Cline, J.M, Sahlin, L

“…Abstract Objective There is evidence that long-term hormone replacement therapy (HRT) is associated with an increased breast cancer risk. The aim of this study…”
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Effects of long-term HRT and tamoxifen on the expression of progesterone receptors A and B in breast tissue from surgically postmenopausal cynomolgus macaques by ISAKSSON, E, WANG, H, SAHLIN, L, VON SCHOULTZ, B, CLINE, J. M, VON SCHOULTZ, E

“…Estrogen is a well-known mitogen in breast epithelium but the role of progesterone is complex and incompletely understood. In contrast to what is seen in the…”
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Abelian dark matter models for 511 keV γ rays and direct detection by Cline, J.M., Frey, A.R.

“…The authors construct a simple U(1) hidden sector model of metastable dark matter that could explain excess 511 keV gamma rays from the galactic center as…”
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Soy isoflavonoid effects on endogenous estrogen metabolism in postmenopausal female monkeys by Wood, Charles E., Register, Thomas C., Cline, J.Mark

“…Endogenous estrogens are important determinants of breast cancer risk in postmenopausal women. In this study we evaluated the effects of dietary soy…”
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Brentuximab Vedotin in Frontline Therapy of Hodgkin Lymphoma in Patients with Significant Comorbidities Ineligible for Standard Chemotherapy (SGN35-015 Part E) by Yasenchak, Christopher A., Bordoni, Rodolfo, Patel-Donnelly, Dipti, Larson, Timothy, Goldschmidt, Jerome, Boccia, Ralph V., Cline, Vivian J.M., Mamidipalli, Adrija, Liu, Jingmin, Beck, Joseph T.

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Frontline brentuximab vedotin in combination with dacarbazine or bendamustine in patients aged ≥60 years with HL by Friedberg, Jonathan W., Forero-Torres, Andres, Bordoni, Rodolfo E., Cline, Vivian J.M., Patel Donnelly, Dipti, Flynn, Patrick J., Olsen, Gregg, Chen, Robert, Fong, Abraham, Wang, Yinghui, Yasenchak, Christopher A.

“…Patients aged ≥60 years with treatment-naive Hodgkin lymphoma (HL) have few treatment options and inferior survival due to treatment-related toxicities and…”
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Polycystic Ovary Syndrome with Endometrial Hyperplasia in a Cynomolgus Monkey (Macaca fascicularis) by Arifin, E, Shively, C.A, Register, T.C, Cline, J.M

“…A 13-year-old, obese, female cynomolgus monkey (Macaca fascicularis) was observed in a 5-year neurobehavioral study and was humanely euthanatized for…”
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Brentuximab vedotin with dacarbazine or nivolumab as frontline cHL therapy for older patients ineligible for chemotherapy by Friedberg, Jonathan W., Bordoni, Rodolfo, Patel-Donnelly, Dipti, Larson, Timothy, Goldschmidt, Jerome, Boccia, Ralph, Cline, Vivian J. M., Mamidipalli, Adrija, Liu, Jingmin, Akyol, Alev, Yasenchak, Christopher A.

“…•With a median follow-up of 63.6 months, mPFS of patients aged ≥60 years with cHL treated with upfront BV-DTIC was 47.2 months.•Noncomparatively, mPFS of…”
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Effects of soybean glyceollins and estradiol in postmenopausal female monkeys by Wood, C.E, Clarkson, T.B, Appt, S.E, Franke, A.A, Boue, S.M, Burow, M.E, McCoy, T, Cline, J.M

“…Glyceollins are a novel class of soybean phytoalexins with potential cancer-protective antiestrogenic effects. The purpose of this study was to evaluate the…”
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Dynamical instability of brane solutions with a self-tuning cosmological constant by Binétruy, P., Cline, J.M., Grojean, C.

“…A five-dimensional solution to Einstein's equations coupled to a scalar field has been proposed as a partial solution to the cosmological constant problem: the…”
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Effects of prior oral contraceptive use and soy isoflavonoids on estrogen-metabolizing cytochrome P450 enzymes by Scott, L.M., Durant, P., Leone-Kabler, S., Wood, C.E., Register, T.C., Townsend, A., Cline, J.M.

“…Estrogen exposure and metabolism may play an important role in the development of estrogen-sensitive cancers in postmenopausal women. In this study we…”
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Was the electroweak phase transition preceded by a color-broken phase? by Cline, James M., Moore, Guy D., Servant, Géraldine

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Health potential of soy isoflavones for menopausal women by Anderson, John JB, Anthony, Mary S, Cline, J Mark, Washburn, Scott A, Garner, Sanford C

“…To review the current literature on the effects of soy isoflavones, one class of phyto-oestrogens, on cardiovascular diseases, osteoporosis, cancer and…”
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Frontline Brentuximab Vedotin As Monotherapy or in Combination for Older Hodgkin Lymphoma Patients by Yasenchak, Christopher A., Bordoni, Rodolfo, Patel-Donnelly, Dipti, Larson, Timothy, Goldschmidt, Jerome, Boccia, Ralph V., Cline, Vivian J.M., Sacchi, Mariana, Forero-Torres, Andres, Sims, Robert B., Liu, Jingmin, Friedberg, Jonathan W.

“…Introduction: Older patients with classical Hodgkin lymphoma (cHL) have poor outcomes relative to younger patients, often due to comorbidities and toxicities…”
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Hyperplastic and Neoplastic Lesions of the Mammary Gland in Macaques by Wood, C.E, Usborne, A.L, Starost, M.F, Tarara, R.P, Hill, L.R, Wilkinson, L.M, Geisinger, K.R, Feiste, E.A, Cline, J.M

“…Macaques provide an important animal model for the study of hormonal agents and their effects on risk biomarkers for breast cancer. A common criticism of this…”
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Cystic Mammary Adenocarcinoma Associated with a Prolactin-secreting Pituitary Adenoma in a New Zealand White Rabbit (Oryctolagus cuniculus) by Sikoski, P, Trybus, J, Cline, J.M, Muhammad, F.S, Eckhoff, A, Tan, J, Lockard, M, Jolley, T, Britt, S, Kock, N.D

“…A 44-mo-old, female, nulliparous New Zealand White Rabbit (Oryctolagus cuniculus) presented with bilaterally diffusely enlarged mammary glands with enlarged,…”
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Neoplasms of the reproductive tract: the role of hormone exposure by Cline, J.M

“…Cancers of the reproductive system are a major source of morbidity and mortality among women worldwide. Because the uterus, ovaries, and cervix are hormonally…”
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Histologic and Immunohistochemical Characterization of Spontaneous Pituitary Adenomas in Fourteen Cynomolgus Macaques (Macaca fascicularis) by Remick, A.K, Wood, C.E, Cann, J.A, Gee, M.K, Feiste, E.A, Kock, N.D, Cline, J.M

“…Pituitary adenomas were identified in 14 of 491 (2.9%) cynomolgus macaques evaluated from 1994 to 2004. Cases included male (8) and female (6) cynomolgus…”
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