Search Results - "Cline, J. M."

Decidualization of Endometriosis in Macaques by Atkins, H. M., Lombardini, E. D., Caudell, D. L., Appt, S. E., Dubois, A., Cline, J. M.

“…The decidua is the superficial portion of endometrium that transforms, or decidualizes, under the influence of progesterone to nourish the early embryo during…”
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Sigma-2 receptors as a biomarker of proliferation in solid tumours by WHEELER, K. T, WANG, L.-M, WALLEN, C. A, CHILDERS, S. R, CLINE, J. M, KENG, P. C, MACH, R. H

“…Over the past several years, our group has provided considerable evidence that the expression of sigma-2 (sigma2) receptors may serve as a biomarker of tumour…”
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Progestin Treatment Induces Apoptosis and Modulates Transforming Growth Factor-β in the Uterine Endometrium by RODRIGUEZ, Gustavo C, RIMEL, B. J, WATKIN, William, TURBOV, Jane M, BARRY, Cathy, HONGYAN DU, MAXWELL, George L, CLINE, J. M

“…Background: Epidemiologic, animal, and human data suggest that progestins are potent endometrial cancer preventive agents. In the ovarian surface epithelium,…”
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Histiocytes and Histiocytosis by Cline, Martin J.

“…The term histiocyte refers to cells of either the macrophage or Langerhans cell lineages. The histiocytic disorders are characterized by the proliferation of…”
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17-β Estradiol reduces atherosclerosis without exacerbating lupus in ovariectomized systemic lupus erythematosus-susceptible LDLr−/− mice by Shelton, K.A, Cline, J.M, Cann, J.A

“…Abstract Objective To test the hypothesis that estrogen treatment in a radiation chimera mouse model of systemic lupus erythematosus (SLE) and atherosclerosis…”
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Effects of prior oral contraceptive use and soy isoflavonoids on estrogen-metabolizing cytochrome P450 enzymes by Scott, L.M., Durant, P., Leone-Kabler, S., Wood, C.E., Register, T.C., Townsend, A., Cline, J.M.

“…Estrogen exposure and metabolism may play an important role in the development of estrogen-sensitive cancers in postmenopausal women. In this study we…”
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Effects of hormone replacement therapy on the mammary gland of surgically postmenopausal cynomolgus macaques by Cline, J.Mark, Soderqvist, Gunnar, von Schoultz, Eva, Skoog, Lambert, von Schoultz, Bo

“…OBJECTIVE: Our purpose was to define the proliferative response and receptor status in the mammary glands of surgically postmenopausal macaques given hormone…”
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Effects of mammalian and plant estrogens on mammary glands and uteri of macaques by FOTH, D, CLINE, J. M

“…Because of their possible beneficial effects on atherosclerosis and cancer risk, soy-derived isoflavone phytoestrogens may be useful as a dietary alternative…”
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Effects of tibolone and conventional HRT on the expression of estrogen and progesterone receptors in the breast by Ma, L, Hofling, M, Masironi, B, von Schoultz, B, Cline, J.M, Sahlin, L

“…Abstract Objective There is evidence that long-term hormone replacement therapy (HRT) is associated with an increased breast cancer risk. The aim of this study…”
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Effects of long-term HRT and tamoxifen on the expression of progesterone receptors A and B in breast tissue from surgically postmenopausal cynomolgus macaques by ISAKSSON, E, WANG, H, SAHLIN, L, VON SCHOULTZ, B, CLINE, J. M, VON SCHOULTZ, E

“…Estrogen is a well-known mitogen in breast epithelium but the role of progesterone is complex and incompletely understood. In contrast to what is seen in the…”
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Hyperplastic and Neoplastic Lesions of the Mammary Gland in Macaques by Wood, C.E, Usborne, A.L, Starost, M.F, Tarara, R.P, Hill, L.R, Wilkinson, L.M, Geisinger, K.R, Feiste, E.A, Cline, J.M

“…Macaques provide an important animal model for the study of hormonal agents and their effects on risk biomarkers for breast cancer. A common criticism of this…”
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Cervical and Vaginal Epithelial Neoplasms in Cynomolgus Monkeys by Wood, C. E., Borgerink, H., Register, T. C., Scott, L., Cline, J. M.

“…Papillomavirus-associated cervical cancer is the second most common neoplasm in women but has rarely been reported in animals. This report describes cervical…”
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The potential of soybean phytoestrogens for postmenopausal hormone replacement therapy by Clarkson, T B, Anthony, M S, Williams, J K, Honoré, E K, Cline, J M

“…Hormone replacement therapy for postmenopausal women greatly reduces their risk of coronary heart disease. However, current pharmaceutical regimens have a low…”
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Rearrangement of the p53 Gene in Human Osteogenic Sarcomas by Masuda, H., Miller, C., Koeffler, H. P., Battifora, H., Cline, M. J.

“…p53 is a 53-kDa nuclear protein that is associated with malignant transformation in several tumor model systems. In a survey of 134 human carcinomas, sarcomas,…”
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Alterations in the p53 Gene and the Clonal Evolution of the Blast Crisis of Chronic Myelocytic Leukemia by Ahuja, H., Bar-Eli, M., Advani, S. H., Benchimol, S., Cline, M. J.

“…Molecular mechanisms responsible for the clinical progression of chronic myelocytic leukemia to its accelerated phase or to blast crisis have not been defined…”
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Dynamical instability of brane solutions with a self-tuning cosmological constant by Binétruy, P., Cline, J.M., Grojean, C.

“…A five-dimensional solution to Einstein's equations coupled to a scalar field has been proposed as a partial solution to the cosmological constant problem: the…”
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Changes in microvascular density differentiate metabolic health outcomes in monkeys with prior radiation exposure and subsequent skeletal muscle ECM remodeling by Fanning, K M, Pfisterer, B, Davis, A T, Presley, T D, Williams, I M, Wasserman, D H, Cline, J M, Kavanagh, K

“…Radiation exposure accelerates the onset of age-related diseases such as diabetes, cardiovascular disease, and neoplasia and, thus, lends insight into in vivo…”
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Histologic and Immunohistochemical Characterization of Spontaneous Pituitary Adenomas in Fourteen Cynomolgus Macaques (Macaca fascicularis) by Remick, A.K, Wood, C.E, Cann, J.A, Gee, M.K, Feiste, E.A, Kock, N.D, Cline, J.M

“…Pituitary adenomas were identified in 14 of 491 (2.9%) cynomolgus macaques evaluated from 1994 to 2004. Cases included male (8) and female (6) cynomolgus…”
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The effect of long-term treatment with steroid hormones or tamoxifen on oestrogen receptors (alpha and beta) in the endometrium of ovariectomized cynomolgus macaques by Wang, H, Isaksson, E, Von Schoultz, B, Cline, JM, Sahlin, L

“…The effects of oestrogen are mediated by two specific intracellular receptors, oestrogen receptors (ER) alpha and beta, which function as ligand-activated…”
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The Molecular Basis of Leukemia by Cline, Martin J

“…Genes involved in the pathogenesis of cancer are thought to act by two general mechanisms. The first involves the structural alteration of a normal gene (a…”
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