Search Results - "Climent, Miguel"

Long-term effects of waste brick powder addition in the microstructure and service properties of mortars by Ortega, José Marcos, Letelier, Viviana, Solas, Carlos, Moriconi, Giacomo, Climent, Miguel Ángel, Sánchez, Isidro

“…•The addition of brick powder produced a higher microstructure refinement of mortars.•Impedance spectroscopy results show the joint pozzolanic and filler…”
Get full text

Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a randomised controlled superiority trial with a parallel HER2-negative cohort by Gianni, Luca, Dr, Eiermann, Wolfgang, MD, Semiglazov, Vladimir, MD, Manikhas, Alexey, MD, Lluch, Ana, MD, Tjulandin, Sergey, MD, Zambetti, Milvia, MD, Vazquez, Federico, MD, Byakhow, Mikhail, MD, Lichinitser, Mikhail, MD, Climent, Miguel Angel, MD, Ciruelos, Eva, MD, Ojeda, Belén, MD, Mansutti, Mauro, MD, Bozhok, Alla, MD, Baronio, Roberta, MSci, Feyereislova, Andrea, MD, Barton, Claire, MD, Valagussa, Pinuccia, Baselga, Jose, MD

“…Summary Background The monoclonal antibody trastuzumab has survival benefit when given with chemotherapy to patients with early, operable, and metastatic…”
Get full text

Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma by Bellmunt, Joaquim, de Wit, Ronald, Vaughn, David J, Fradet, Yves, Lee, Jae-Lyun, Fong, Lawrence, Vogelzang, Nicholas J, Climent, Miguel A, Petrylak, Daniel P, Choueiri, Toni K, Necchi, Andrea, Gerritsen, Winald, Gurney, Howard, Quinn, David I, Culine, Stéphane, Sternberg, Cora N, Mai, Yabing, Poehlein, Christian H, Perini, Rodolfo F, Bajorin, Dean F

“…In a randomized trial involving 542 patients with relapsed urothelial cancer, treatment with pembrolizumab resulted in overall survival of more than 10 months,…”
Get full text

Use of Non-Linear Ultrasonic Techniques to Detect Cracks Due to Steel Corrosion in Reinforced Concrete Structures by Climent, Miguel Ángel, Miró, Marina, Carbajo, Jesús, Poveda, Pedro, de Vera, Guillem, Ramis, Jaime

“…In this work, non-linear ultrasonic wave techniques have been used to detect the onset of micro-cracking due to steel corrosion in model reinforced concrete…”
Get full text

Pembrolizumab plus lenvatinib as first-line therapy for advanced non-clear-cell renal cell carcinoma (KEYNOTE-B61): a single-arm, multicentre, phase 2 trial by Albiges, Laurence, Gurney, Howard, Atduev, Vagif, Suarez, Cristina, Climent, Miguel A, Pook, David, Tomczak, Piotr, Barthelemy, Philippe, Lee, Jae Lyun, Stus, Viktor, Ferguson, Thomas, Wiechno, Pawel, Gokmen, Erhan, Lacombe, Louis, Gedye, Craig, Perini, Rodolfo F, Sharma, Manish, Peng, Xiang, Lee, Chung-Han

“…Immunotherapy-based combinations including pembrolizumab plus lenvatinib are the standard of care for patients with first-line clear-cell renal cell carcinoma,…”
Get full text

Randomized Phase II Study of the Anti–Epidermal Growth Factor Receptor Monoclonal Antibody Cetuximab With Cisplatin Versus Cisplatin Alone in Patients With Metastatic Triple-Negative Breast Cancer by BASELGA, José, GOMEZ, Patricia, GOEMINNE, Jean-Charles, GRAAS, Marie-Pascale, KENNEDY, M. John, CIRUELOS GIL, Eva Maria, SCHNEEWEISS, Andreas, ZUBEL, Angela, GROOS, Jutta, MELEZINKOVA, Helena, AWADA, Ahmad, GREIL, Richard, BRAGA, Sofia, CLIMENT, Miguel A, WARDLEY, Andrew M, KAUFMAN, Bella, STEMMER, Salomon M, PEGO, António, CHAN, Arlene

“…Epidermal growth factor receptor is overexpressed in metastatic triple-negative breast cancers (mTNBCs), an aggressive subtype of breast cancer. Our randomized…”
Get full text

Health-Related Quality-of-Life Analysis From KEYNOTE-045: A Phase III Study of Pembrolizumab Versus Chemotherapy for Previously Treated Advanced Urothelial Cancer by Vaughn, David J, Bellmunt, Joaquim, Fradet, Yves, Lee, Jae Lyun, Fong, Lawrence, Vogelzang, Nicholas J, Climent, Miguel A, Petrylak, Daniel P, Choueiri, Toni K, Necchi, Andrea, Gerritsen, Winald, Gurney, Howard, Quinn, David I, Culine, Stephane, Sternberg, Cora N, Mai, Yabing, Li, Haojie, Perini, Rodolfo F, Bajorin, Dean F, de Wit, Ronald

“…Purpose In the phase III KEYNOTE-045 study ( ClinicalTrials.gov identifier: NCT02256436), pembrolizumab significantly prolonged overall survival compared with…”
Get full text

Performance of Sustainable Fly Ash and Slag Cement Mortars Exposed to Simulated and Real In Situ Mediterranean Conditions along 90 Warm Season Days by Ortega, José Marcos, Esteban, María Dolores, Sánchez, Isidro, Climent, Miguel Ángel

“…Nowadays, cement manufacture is one of the most polluting worldwide industrial sectors. In order to reduce its CO₂ emissions, the clinker replacement by ground…”
Get full text

Adjuvant Ovarian Suppression in Premenopausal Breast Cancer by Francis, Prudence A, Regan, Meredith M, Fleming, Gini F, Láng, István, Ciruelos, Eva, Bellet, Meritxell, Bonnefoi, Hervé R, Climent, Miguel A, Da Prada, Gian Antonio, Burstein, Harold J, Martino, Silvana, Davidson, Nancy E, Geyer, Charles E, Walley, Barbara A, Coleman, Robert, Kerbrat, Pierre, Buchholz, Stefan, Ingle, James N, Winer, Eric P, Rabaglio-Poretti, Manuela, Maibach, Rudolf, Ruepp, Barbara, Giobbie-Hurder, Anita, Price, Karen N, Colleoni, Marco, Viale, Giuseppe, Coates, Alan S, Goldhirsch, Aron, Gelber, Richard D

“…This trial did not support routine use of ovarian suppression in premenopausal breast cancer. Nevertheless, there may be some benefit from ovarian suppression…”
Get full text

Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study by Garcia-Donas, Jesus, MD, Esteban, Emilio, MD, Leandro-García, Luis Javier, BSc, Castellano, Daniel E, MD, del Alba, Aranzazu González, MD, Climent, Miguel Angel, MD, Arranz, José Angel, MD, Gallardo, Enrique, MD, Puente, Javier, MD, Bellmunt, Joaquim, MD, Mellado, Begoña, MD, Martínez, Esther, MD, Moreno, Fernando, MD, Font, Albert, MD, Robledo, Mercedes, PhD, Rodríguez-Antona, Cristina, Dr

“…Summary Background Sunitinib is a tyrosine kinase inhibitor with proven efficacy in renal-cell carcinoma, but some patients do not respond or need dose…”
Get full text

Impedance Spectroscopy Study of the Effect of Environmental Conditions on the Microstructure Development of Sustainable Fly Ash Cement Mortars by Ortega, José Marcos, Sánchez, Isidro, Climent, Miguel Ángel

“…Today, the characterisation of the microstructure of cement-based materials using non-destructive techniques has become an important topic of study, and among…”
Get full text

Patient-reported Outcomes from JAVELIN Bladder 100: Avelumab First-line Maintenance Plus Best Supportive Care Versus Best Supportive Care Alone for Advanced Urothelial Carcinoma by Grivas, Petros, Kopyltsov, Evgeny, Su, Po-Jung, Parnis, Francis X., Park, Se Hoon, Yamamoto, Yoshiaki, Fong, Peter C., Tournigand, Christophe, Climent Duran, Miguel A., Bamias, Aristotelis, Caserta, Claudia, Chang, Jane, Cislo, Paul, di Pietro, Alessandra, Wang, Jing, Powles, Thomas

“…In patients with advanced urothelial carcinoma who were progression free following platinum-containing chemotherapy, first-line maintenance therapy with…”
Get full text

Safety of cabazitaxel in senior adults with metastatic castration-resistant prostate cancer: Results of the European compassionate-use programme by Heidenreich, Axel, Bracarda, Sergio, Mason, Malcolm, Ozen, Haluk, Sengelov, Lisa, Van Oort, Inge, Papandreou, Christos, Fossa, Sophie, Hitier, Simon, Climent, Miguel Angel

“…Abstract Background Cabazitaxel/prednisone has been shown to prolong survival versus mitoxantrone/prednisone in patients with metastatic castration-resistant…”
Get full text

Neoadjuvant and adjuvant trastuzumab in patients with HER2-positive locally advanced breast cancer (NOAH): follow-up of a randomised controlled superiority trial with a parallel HER2-negative cohort by Gianni, Luca, Dr, Eiermann, Wolfgang, MD, Semiglazov, Vladimir, MD, Lluch, Ana, PhD, Tjulandin, Sergei, MD, Zambetti, Milvia, MD, Moliterni, Angela, MD, Vazquez, Federico, MD, Byakhov, Mikhail J, PhD, Lichinitser, Mikhail, MD, Climent, Miguel Angel, MD, Ciruelos, Eva, MD, Ojeda, Belen, MD, Mansutti, Mauro, MD, Bozhok, Alla, PhD, Magazzù, Domenico, PhD, Heinzmann, Dominik, PhD, Steinseifer, Jutta, PhD, Valagussa, Pinuccia, BS, Baselga, Jose, MD

“…Summary Background In our randomised, controlled, phase 3 trial NeOAdjuvant Herceptin (NOAH) trial in women with HER2-positive locally advanced or inflammatory…”
Get full text

Effect of a Crystalline Admixture on the Permeability Properties of Concrete and the Resistance to Corrosion of Embedded Steel by Antón, Carlos, Gurdián, Hebé, de Vera, Guillem, Climent, Miguel-Ángel

“…Reinforced concrete structure durability hinges on concrete permeability, which relies on the characteristics of the inner porous network. Harmful ions and…”
Get full text

Short-Term Behavior of Slag Concretes Exposed to a Real In Situ Mediterranean Climate Environment by Ortega, José Marcos, Sánchez, Isidro, Cabeza, Marta, Climent, Miguel Ángel

“…At present, one of the most suitable ways to get a more sustainable cement industry is to reduce the CO₂ emissions generated during cement production. In order…”
Get full text

Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy by Bellet, Meritxell, Gray, Kathryn P, Francis, Prudence A, Láng, István, Ciruelos, Eva, Lluch, Ana, Climent, Miguel Angel, Catalán, Gustavo, Avella, Antoni, Bohn, Uriel, González-Martin, Antonio, Ferrer, Roser, Catalán, Roberto, Azaro, Analía, Rajasekaran, Agnita, Morales, Josefa, Vázquez, Josep, Fleming, Gini F, Price, Karen N, Regan, Meredith M

“…To describe estradiol (E2), estrone (E1), and estrone sulfate (E1S) levels during the first year of monthly triptorelin plus exemestane or tamoxifen and to…”
Get full text

Avelumab First-line Maintenance for Advanced Urothelial Carcinoma: Analysis from JAVELIN Bladder 100 by Duration of First-line Chemotherapy and Interval Before Maintenance by Sridhar, Srikala S., Powles, Thomas, Climent Durán, Miguel Á., Park, Se Hoon, Massari, Francesco, Thiery-Vuillemin, Antoine, Valderrama, Begoña P., Ullén, Anders, Tsuchiya, Norihiko, Aragon-Ching, Jeanny B., Gupta, Shilpa, Petrylak, Daniel P., Bellmunt, Joaquim, Wang, Jing, Laliberte, Robert J., di Pietro, Alessandra, Costa, Nuno, Grivas, Petros, Sternberg, Cora N., Loriot, Yohann

“…In JAVELIN Bladder 100, results from analyses of overall survival and progression-free survival with avelumab first-line maintenance + best supportive care…”
Get full text

Early colonization of sessile megabenthos on electrolytic carbonated structures (Alicante's harbor, Western Mediterranean) by Carmona-Rodríguez, Alejandro, Antón, Carlos, Climent, Miguel Ángel, Garcés, Pedro, Montiel, Vicente, Ramos-Esplá, Alfonso A.

“…Biofouling of different artificial substrates was studied to determine the differences in biofouling assemblages among different substrates. However, studies…”
Get full text

Effects of Red Mud Addition in the Microstructure, Durability and Mechanical Performance of Cement Mortars by Ortega, José, Cabeza, Marta, Tenza-Abril, Antonio, Real-Herraiz, Teresa, Climent, Miguel, Sánchez, Isidro

“…Recently, there has been a great effort to incorporate industrial waste into cement-based materials to reach a more sustainable cement industry. In this…”
Get full text