Search Results - "Climent, A."

New rocking column with control of negative stiffness displacement range and its application to RC frames by Ríos-García, G., Benavent-Climent, A.

“…•New rocking column without adverse effects of PT tendons anchored at both ends.•Vertically restrained with steel bar anchored at top and free to slip at…”
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Earthquake retrofitting of R/C frames with soft first story using hysteretic dampers: Energy-based design method and evaluation by Benavent-Climent, A., Mota-Páez, S.

“…•Takes advantage of the tendency for building to concentrate damage in first story.•The behavior of the retrofitted structure comes close to a base-isolated…”
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Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma by Bellmunt, Joaquim, de Wit, Ronald, Vaughn, David J, Fradet, Yves, Lee, Jae-Lyun, Fong, Lawrence, Vogelzang, Nicholas J, Climent, Miguel A, Petrylak, Daniel P, Choueiri, Toni K, Necchi, Andrea, Gerritsen, Winald, Gurney, Howard, Quinn, David I, Culine, Stéphane, Sternberg, Cora N, Mai, Yabing, Poehlein, Christian H, Perini, Rodolfo F, Bajorin, Dean F

“…In a randomized trial involving 542 patients with relapsed urothelial cancer, treatment with pembrolizumab resulted in overall survival of more than 10 months,…”
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The precise determination of the window of implantation significantly improves ART outcomes by Enciso, M., Aizpurua, J., Rodríguez-Estrada, B., Jurado, I., Ferrández-Rives, M., Rodríguez, E., Pérez-Larrea, E., Climent, A. B., Marron, K., Sarasa, J.

“…The human endometrium is receptive to the embryo for a specific period of time known as the window of implantation (WOI). During this period, the endometrium…”
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Seismic strengthening of low-rise reinforced concrete frame structures with masonry infill walls: Shaking-table test by Benavent-Climent, A., Ramírez-Márquez, A., Pujol, S.

“…•RC frames with infills are tested on a shaking table up to intolerable drifts.•The system endured drift ratios close to 5% without signs of catastrophic…”
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Patient-reported Outcomes from JAVELIN Bladder 100: Avelumab First-line Maintenance Plus Best Supportive Care Versus Best Supportive Care Alone for Advanced Urothelial Carcinoma by Grivas, Petros, Kopyltsov, Evgeny, Su, Po-Jung, Parnis, Francis X., Park, Se Hoon, Yamamoto, Yoshiaki, Fong, Peter C., Tournigand, Christophe, Climent Duran, Miguel A., Bamias, Aristotelis, Caserta, Claudia, Chang, Jane, Cislo, Paul, di Pietro, Alessandra, Wang, Jing, Powles, Thomas

“…In patients with advanced urothelial carcinoma who were progression free following platinum-containing chemotherapy, first-line maintenance therapy with…”
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Randomized Phase II Study of the Anti–Epidermal Growth Factor Receptor Monoclonal Antibody Cetuximab With Cisplatin Versus Cisplatin Alone in Patients With Metastatic Triple-Negative Breast Cancer by BASELGA, José, GOMEZ, Patricia, GOEMINNE, Jean-Charles, GRAAS, Marie-Pascale, KENNEDY, M. John, CIRUELOS GIL, Eva Maria, SCHNEEWEISS, Andreas, ZUBEL, Angela, GROOS, Jutta, MELEZINKOVA, Helena, AWADA, Ahmad, GREIL, Richard, BRAGA, Sofia, CLIMENT, Miguel A, WARDLEY, Andrew M, KAUFMAN, Bella, STEMMER, Salomon M, PEGO, António, CHAN, Arlene

“…Epidermal growth factor receptor is overexpressed in metastatic triple-negative breast cancers (mTNBCs), an aggressive subtype of breast cancer. Our randomized…”
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Health-Related Quality-of-Life Analysis From KEYNOTE-045: A Phase III Study of Pembrolizumab Versus Chemotherapy for Previously Treated Advanced Urothelial Cancer by Vaughn, David J, Bellmunt, Joaquim, Fradet, Yves, Lee, Jae Lyun, Fong, Lawrence, Vogelzang, Nicholas J, Climent, Miguel A, Petrylak, Daniel P, Choueiri, Toni K, Necchi, Andrea, Gerritsen, Winald, Gurney, Howard, Quinn, David I, Culine, Stephane, Sternberg, Cora N, Mai, Yabing, Li, Haojie, Perini, Rodolfo F, Bajorin, Dean F, de Wit, Ronald

“…Purpose In the phase III KEYNOTE-045 study ( ClinicalTrials.gov identifier: NCT02256436), pembrolizumab significantly prolonged overall survival compared with…”
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An energy-based damage model for seismic response of steel structures by Benavent-Climent, A.

“…This paper proposes a new model for quantifying the damage in structural steel components subjected to randomly applied flexural/shear stress reversals, such…”
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The Motor Cortex Is Involved in the Generation of Classically Conditioned Eyelid Responses in Behaving Rabbits by Ammann, Claudia, Márquez-Ruiz, Javier, Gómez-Climent, María Á, Delgado-García, José M, Gruart, Agnès

“…Classical blink conditioning is a well known model for studying neural generation of acquired motor responses. The acquisition of this type of associative…”
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Activation of the PP2A-B56α heterocomplex synergizes with venetoclax therapies in AML through BCL2 and MCL1 modulation by Peris, Irene, Romero-Murillo, Silvia, Martínez-Balsalobre, Elena, Farrington, Caroline C., Arriazu, Elena, Marcotegui, Nerea, Jiménez-Muñoz, Marta, Alburquerque-Prieto, Cristina, Torres-López, Andrea, Fresquet, Vicente, Martínez-Climent, Jose A., Mateos, Maria C., Cayuela, Maria L., Narla, Goutham, Odero, Maria D., Vicente, Carmen

“…•PP2A activators enhance the efficacy of venetoclax and venetoclax-azacitidine combination in primary samples and preclinical models of AML.•PP2A-B56α…”
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Chronic docosahexaenoic acid supplementation improves metabolic plasticity in subcutaneous adipose tissue of aged obese female mice by Félix-Soriano, Elisa, Sáinz, Neira, Fernández-Galilea, Marta, Gil-Iturbe, Eva, Celay, Jon, Martínez-Climent, José A., Moreno-Aliaga, María J.

“…This study aimed to characterize the potential beneficial effects of chronic docosahexaenoic acid (DHA) supplementation on restoring subcutaneous white adipose…”
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C/EBPα Induces Highly Efficient Macrophage Transdifferentiation of B Lymphoma and Leukemia Cell Lines and Impairs Their Tumorigenicity by Rapino, Francesca, Robles, Eloy F., Richter-Larrea, Jose A., Kallin, Eric M., Martinez-Climent, Jose A., Graf, Thomas

“…Earlier work demonstrated that the transcription factor C/EBPα can convert immature and mature murine B lineage cells into functional macrophages. Testing >20…”
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Imageless electrocardiographic imaging for atrial electrophysiological characterization: a validation study by Ros, S, Reventos, J, Fambuena, C, Lundback, D, Arenal, A, Torrecilla, E G, Avila, P, Carta, A, Bermejo, J, Mombiela, T, Delgado, A, Climent, A M, Guillem, M S, Atienza, F

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Frequent mutations in the amino-terminal domain of BCL7A impair its tumor suppressor role in DLBCL by Baliñas-Gavira, Carlos, Rodríguez, María I., Andrades, Alvaro, Cuadros, Marta, Álvarez-Pérez, Juan Carlos, Álvarez-Prado, Ángel F., de Yébenes, Virginia G., Sánchez-Hernández, Sabina, Fernández-Vigo, Elvira, Muñoz, Javier, Martín, Francisco, Ramiro, Almudena R., Martínez-Climent, José A., Medina, Pedro P.

“…Mutations in genes encoding subunits of the SWI/SNF chromatin remodeling complex are frequently found in different human cancers. While the tumor suppressor…”
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Immediate and after effects of transcranial direct-current stimulation in the mouse primary somatosensory cortex by Sánchez-León, Carlos A., Cordones, Isabel, Ammann, Claudia, Ausín, José M., Gómez-Climent, María A., Carretero-Guillén, Alejandro, Sánchez-Garrido Campos, Guillermo, Gruart, Agnès, Delgado-García, José M., Cheron, Guy, Medina, Javier F., Márquez-Ruiz, Javier

“…Transcranial direct-current stimulation (tDCS) is a non-invasive brain stimulation technique consisting in the application of weak electric currents on the…”
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Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia by San José-Eneriz, Edurne, Agirre, Xabier, Jiménez-Velasco, Antonio, Cordeu, Lucia, Martín, Vanesa, Arqueros, Victor, Gárate, Leire, Fresquet, Vicente, Cervantes, Francisco, Martínez-Climent, José A, Heiniger, Anabel, Torres, Antonio, Prósper, Felipe, Roman-Gomez, Jose

“…Abstract Background Expression of the pro-apoptotic BCL-2-interacting mediator ( BIM ) has recently been implicated in imatinib-induced apoptosis of BCR-ABL1+…”
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Stress transfer patterns and local seismicity related to reservoir water-level variations. A case study in central Costa Rica by Ruiz-Barajas, S., Santoyo, M. A., Benito Oterino, M. B., Alvarado, G. E., Climent, A.

“…This study main aim was to analyse the spatio-temporal trend in seismicity recorded in the proximity of the Pirrís Reservoir (central Costa Rica), where…”
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Chemical, Thermal and Spectroscopic Methods to Assess Biodegradation of Winery-Distillery Wastes during Composting by Torres-Climent, A, Gomis, P, Martín-Mata, J, Bustamante, M A, Marhuenda-Egea, F C, Pérez-Murcia, M D, Pérez-Espinosa, A, Paredes, C, Moral, R

“…The objective of this work was to study the co-composting process of wastes from the winery and distillery industry with animal manures, using the classical…”
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Minimal configuration of body surface potential mapping for discrimination of left versus right dominant frequencies during atrial fibrillation by Rodrigo, M., Climent, A.M., Liberos, A., Fernández‐Aviles, F., Atienza, F., Guillem, M.S., Berenfeld, O.

“…Background Ablation of drivers maintaining atrial fibrillation (AF) has been demonstrated as an effective therapy. Drivers in the form of rapidly activated…”
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