Search Results - "Cliff, Penelope"

High-resolution genotyping of Lymphogranuloma Venereum (LGV) strains of Chlamydia trachomatis in London using multi-locus VNTR analysis-ompA genotyping (MLVA-ompA) by Manning, Chloe, O'Neill, Colette, Clarke, Ian N, Rebec, Monica, Cliff, Penelope R, Marsh, Peter

“…Lymphogranuloma venereum (LGV) is caused by Chlamydia trachomatis strains with ompA genotypes L1 to L3. An LGV epidemic associated with the L2b genotype has…”
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Comparative performance of SARS-CoV-2 lateral flow antigen tests and association with detection of infectious virus in clinical specimens: a single-centre laboratory evaluation study by Pickering, Suzanne, Batra, Rahul, Merrick, Blair, Snell, Luke B, Nebbia, Gaia, Douthwaite, Sam, Reid, Fiona, Patel, Amita, Kia Ik, Mark Tan, Patel, Bindi, Charalampous, Themoula, Alcolea-Medina, Adela, Lista, Maria Jose, Cliff, Penelope R, Cunningham, Emma, Mullen, Jane, Doores, Katie J, Edgeworth, Jonathan D, Malim, Michael H, Neil, Stuart J D, Galão, Rui Pedro

“…Lateral flow devices (LFDs) for rapid antigen testing are set to become a cornerstone of SARS-CoV-2 mass community testing, although their reduced sensitivity…”
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Routine Metagenomics Service for ICU Patients with Respiratory Infection by Charalampous, Themoula, Alcolea-Medina, Adela, Snell, Luke B, Alder, Christopher, Tan, Mark, Williams, Tom G S, Al-Yaakoubi, Noor, Humayun, Gul, Meadows, Christopher I S, Wyncoll, Duncan L A, Paul, Richard, Hemsley, Carolyn J, Jeyaratnam, Dakshika, Newsholme, William, Goldenberg, Simon, Patel, Amita, Tucker, Fearghal, Nebbia, Gaia, Wilks, Mark, Chand, Meera, Cliff, Penelope R, Batra, Rahul, O'Grady, Justin, Barrett, Nicholas A, Edgeworth, Jonathan D

“…Respiratory metagenomics (RMg) needs evaluation in a pilot service setting to determine utility and inform implementation into routine clinical practice…”
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Rapid genome sequencing in hospitals to identify potential vaccine-escape SARS-CoV-2 variants by Snell, Luke B, Cliff, Penelope R, Charalampous, Themoula, Alcolea-Medina, Adela, Ebie, Saidat A R T, Sehmi, Jasveen K, Flaviani, Flavia, Batra, Rahul, Douthwaite, Sam T, Edgeworth, Jonathan D, Nebbia, Gaia

“…SARS-CoV-2 genome sequencing is embedded in academic and public health laboratories, but whether there are benefits to rapid sequencing in front-line hospital…”
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Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units by Charalampous, Themoula, Alcolea-Medina, Adela, Snell, Luke B, Williams, Tom G S, Batra, Rahul, Alder, Christopher, Telatin, Andrea, Camporota, Luigi, Meadows, Christopher I S, Wyncoll, Duncan, Barrett, Nicholas A, Hemsley, Carolyn J, Bryan, Lisa, Newsholme, William, Boyd, Sara E, Green, Anna, Mahadeva, Ula, Patel, Amita, Cliff, Penelope R, Page, Andrew J, O'Grady, Justin, Edgeworth, Jonathan D

“…Clinical metagenomics (CMg) has the potential to be translated from a research tool into routine service to improve antimicrobial treatment and infection…”
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Performance evaluation of the Viasure PCR assay for the diagnosis of monkeypox: A multicentre study by Tan, Ngee Keong, Madona, Cindy P., Taylor, Joshua F., Fourali, Lynda Hadjilah, Sehmi, Jasveen K., Stone, Madeline J., Pond, Marcus J., Cliff, Penelope R., Pope, Cassie F.

“…•The Viasure MPXV PCR assay demonstrated excellent performance characteristics.•The assay was easy to use and fit for routine diagnostic purpose.•Vesicular…”
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Development of a Multiplex Tandem PCR (MT-PCR) Assay for the Detection of Emerging SARS-CoV-2 Variants by Hale, Richard, Crowley, Peter, Dervisevic, Samir, Coupland, Lindsay, Cliff, Penelope R, Ebie, Saidat, Snell, Luke B, Paul, Joel, Williams, Cheryl, Randell, Paul, Pond, Marcus, Stanley, Keith

“…The emergence of variants of SARS-CoV-2 has created challenges for the testing infrastructure. Although large-scale genome sequencing of SARS-CoV-2 has…”
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Combined epidemiological and genomic analysis of nosocomial SARS-CoV-2 infection early in the pandemic and the role of unidentified cases in transmission by Snell, Luke B., Fisher, Chloe L., Taj, Usman, Stirrup, Oliver, Merrick, Blair, Alcolea-Medina, Adela, Charalampous, Themoula, Signell, Adrian W., Wilson, Harry D., Betancor, Gilberto, Kia Ik, Mark Tan, Cunningham, Emma, Cliff, Penelope R., Pickering, Suzanne, Galao, Rui Pedro, Batra, Rahul, Neil, Stuart J.D., Malim, Michael H., Doores, Katie J., Douthwaite, Sam T., Nebbia, Gaia, Edgeworth, Jonathan D., Awan, Ali R.

“…To analyse nosocomial transmission in the early stages of the coronavirus 2019 (COVID-19) pandemic at a large multisite healthcare institution. Nosocomial…”
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Development and evaluation of a nanopore 16S rRNA gene sequencing service for same day targeted treatment of bacterial respiratory infection in the intensive care unit by Baldan, Rossella, Cliff, Penelope R., Burns, Sarah, Medina, Adela, Smith, Graeme C., Batra, Rahul, Cerda, Alberto, Wilson, Rebekah, Merrill, Tammy, Lewis, Shona J., Patel, Amita, Jeyaratnam, Dakshika, Wyncoll, Duncan L., Barrett, Nicholas, Chand, Meera A., Edgeworth, Jonathan D.

“…•Nanopore sequencing can provide a same day result for respiratory infection on ICU.•Nanopore 16S sequencing was able to identify causative pathogen in 32/33…”
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Selection for qacA carriage in CC22, but not CC30, methicillin-resistant Staphylococcus aureus bloodstream infection isolates during a successful institutional infection control programme by Otter, Jonathan A, Patel, Amita, Cliff, Penelope R, Halligan, Eugene P, Tosas, Olga, Edgeworth, Jonathan D

“…The increasing use of chlorhexidine for methicillin-resistant Staphylococcus aureus (MRSA) decolonization raises concerns about reduced susceptibility. We…”
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Unified metagenomic method for rapid detection of microorganisms in clinical samples by Alcolea-Medina, Adela, Alder, Christopher, Snell, Luke B., Charalampous, Themoula, Aydin, Alp, Nebbia, Gaia, Williams, Tom, Goldenberg, Simon, Douthwaite, Sam, Batra, Rahul, Cliff, Penelope R., Mischo, Hannah, Neil, Stuart, Wilks, Mark, Edgeworth, Jonathan D.

“…Background Clinical metagenomics involves the genomic sequencing of all microorganisms in clinical samples ideally after depletion of human DNA to increase…”
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Publisher Correction: Unified metagenomic method for rapid detection of microorganisms in clinical samples by Alcolea-Medina, Adela, Alder, Christopher, Snell, Luke B., Charalampous, Themoula, Aydin, Alp, Nebbia, Gaia, Williams, Tom, Goldenberg, Simon, Douthwaite, Sam, Batra, Rahul, Cliff, Penelope R., Mischo, Hannah, Neil, Stuart, Wilks, Mark, Edgeworth, Jonathan D.

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Clinical Application of Real-Time PCR to Screening Critically Ill and Emergency-Care Surgical Patients for Methicillin-Resistant Staphylococcus aureus: a Quantitative Analytical Study by Herdman, M. Trent, Wyncoll, Duncan, Halligan, Eugene, Cliff, Penelope R, French, Gary, Edgeworth, Jonathan D

“…The clinical utility of real-time PCR screening assays for methicillin (meticillin)-resistant Staphylococcus aureus (MRSA) colonization is constrained by the…”
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Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses by Tan, Mai Ping, Sequeira, Patricia, Lin, Wen Wei, Phong, Wai Yee, Cliff, Penelope, Ng, Seow Hwee, Lee, Boon Heng, Camacho, Luis, Schnappinger, Dirk, Ehrt, Sabine, Dick, Thomas, Pethe, Kevin, Alonso, Sylvie

“…There are strong evidences that Mycobacterium tuberculosis survives in a non-replicating state in the absence of oxygen in closed lesions and granuloma in…”
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Retrospective survey of candidaemia in hospitalized patients and molecular investigation of a suspected outbreak by Cliff, Penelope R, Sandoe, Jonathan AT, Heritage, John, Barton, Richard C

“…1,3 Mycology Reference Centre 1 and Department of Microbiology 3 , The General Infirmary at Leeds, Leeds LS1 3EX, UK 2 School of Biochemistry and Microbiology,…”
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High-resolution genotyping of Lymphogranuloma Venereum by Manning, Chloe, O'Neill, Colette, Clarke, Ian N, Rebec, Monica, Cliff, Penelope R, Marsh, Peter

“…Background Lymphogranuloma venereum (LGV) is caused by Chlamydia trachomatis strains with ompA genotypes L1 to L3. An LGV epidemic associated with the L2b…”
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The ongoing Streptococcus pyogenes (Group A Streptococcus) outbreak in London, United Kingdom, in December 2022: a molecular epidemiology study by Alcolea-Medina, Adela, Snell, Luke B, Alder, Christopher, Charalampous, Themoula, Williams, Tom G S, Tan, Mark K I, Al-Yaakoubi, Noor, Humayun, Gul, Newsholme, William, Goldenberg, Simon, Nebbia, Gaia, Neil, Stuart J D, Batra, Rahul, Edgeworth, Jonathan D

“…Epidemiological and whole-genome sequencing analysis of an ongoing outbreak of Streptococcus pyogenes (Group A Streptococcus) in London (United Kingdom)…”
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Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation by Lista, Maria Jose, Matos, Pedro M, Maguire, Thomas J A, Poulton, Kate, Ortiz-Zapater, Elena, Page, Robert, Sertkaya, Helin, Ortega-Prieto, Ana M, Scourfield, Edward, O'Byrne, Aoife M, Bouton, Clement, Dickenson, Ruth E, Ficarelli, Mattia, Jimenez-Guardeño, Jose M, Howard, Mark, Betancor, Gilberto, Galao, Rui Pedro, Pickering, Suzanne, Signell, Adrian W, Wilson, Harry, Cliff, Penelope, Kia Ik, Mark Tan, Patel, Amita, MacMahon, Eithne, Cunningham, Emma, Doores, Katie, Agromayor, Monica, Martin-Serrano, Juan, Perucha, Esperanza, Mischo, Hannah E, Shankar-Hari, Manu, Batra, Rahul, Edgeworth, Jonathan, Zuckerman, Mark, Malim, Michael H, Neil, Stuart, Martinez-Nunez, Rocio Teresa

“…There is a worldwide need for reagents to perform SARS-CoV-2 detection. Some laboratories have implemented kit-free protocols, but many others do not have the…”
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Frequency and correlates of Mycoplasma genitalium antimicrobial resistance mutations and their association with treatment outcomes: findings from a national sentinel surveillance pilot in England by Fifer, Helen, Merrick, Rachel, Pitt, Rachel, Yung, Mandy, Allen, Hester, Day, Michaela, Sinka, Katy, Woodford, Neil, Mohammed, Hamish, Brown, Colin S, Hughes, Gwenda, Cole, Michelle, Nori, Achyuta, Evans, Amy, Richardson, Ania, Sullivan, Ann, Macrae, Bruce, Graham, Clive, Padgett, Debra, Page, Emma, Jungmann, Eva, Phattey, Jara, Glascodine, Joanna, Ross, Jonathan, Garvey, Lucy, Phillips, Matthew, Clarke, Michael, Rayment, Michael, Rebec, Monica, Fearnley, Nicola, Wickramasinghe, Nimal, Horner, Paddy, Cliff, Penelope, Muir, Peter, Browne, Rita, Brum, Roberta, Tittle, Victoria

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