Search Results - "Cleva, Richard M."

Glutamatergic medications for the treatment of drug and behavioral addictions by Olive, M. Foster, Cleva, Richard M., Kalivas, Peter W., Malcolm, Robert J.

“…Historically, most pharmacological approaches to the treatment of addictive disorders have utilized either substitution-based methods (i.e., nicotine…”
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Positive allosteric modulators of type 5 metabotropic glutamate receptors (mGluR5) and their therapeutic potential for the treatment of CNS disorders by Cleva, Richard M, Olive, M Foster

“…Studies utilizing selective pharmacological antagonists or targeted gene deletion have demonstrated that type 5 metabotropic glutamate receptors (mGluR5) are…”
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mGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol-seeking behavior by Sinclair, Courtney M., Cleva, Richard M., Hood, Lauren E., Olive, M. Foster, Gass, Justin T.

“…Pharmacological blockade of the type 5 metabotropic glutamate receptor (mGluR5) attenuates cue-induced reinstatement of ethanol-seeking behavior, yet the brain…”
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Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors by Gass, Justin T., Sinclair, Courtney M., Cleva, Richard M., Widholm, John J., Olive, M. Foster

“…ABSTRACT Relapse is one of the most problematic aspects in the treatment of alcoholism and is often triggered by alcohol‐associated environmental cues…”
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mGluR5 Positive Allosteric Modulation Enhances Extinction Learning Following Cocaine Self-Administration by Cleva, Richard M, Hicks, Megan P, Gass, Justin T, Wischerath, Kelly C, Plasters, Elizabeth T, Widholm, John J, Olive, M. Foster

“…Extinction of classically and instrumentally conditioned behaviors, such as conditioned fear and drug-seeking behavior, is a process of active learning, and…”
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Extinction Learning and Adult Neurogenesis by Cleva, Richard M, Wischerath, Kelly C, Olive, M Foster

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Differential Modulation of Thresholds for Intracranial Self-Stimulation by mGlu5 Positive and Negative Allosteric Modulators: Implications for Effects on Drug Self-Administration by Cleva, Richard M, Watterson, Lucas R, Johnson, Meagan A, Olive, M Foster

“…Pharmacological manipulation of the type 5 metabotropic glutamate (mGlu5) receptor alters various addiction related behaviors such as drug self-administration…”
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Extinction Learning and Adult Neurogenesis: Cognition by CLEVA, Richard M, WISCHERATH, Kelly C, OLIVE, M. Foster

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Glutamatergic medications for the treatment of drug and behavioral addictions: Glutamate Receptors by FOSTER OLIVE, M, CLEVA, Richard M, KALIVAS, Peter W, MALCOLM, Robert J

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