Search Results - "Cleutjens, J. P. M."

Diet-induced weight loss decreases adipose tissue oxygen tension with parallel changes in adipose tissue phenotype and insulin sensitivity in overweight humans by Vink, R G, Roumans, N J, Čajlaković, M, Cleutjens, J P M, Boekschoten, M V, Fazelzadeh, P, Vogel, M A A, Blaak, E E, Mariman, E C, van Baak, M A, Goossens, G H

“…BACKGROUND/OBJECTIVES: Although adipose tissue (AT) hypoxia is present in rodent models of obesity, evidence for this in humans is limited. Here, we…”
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Cell kinetics of the marine sponge Halisarca caerulea reveal rapid cell turnover and shedding by De Goeij, J M, De Kluijver, A, Van Duyl, F C, Vacelet, J, Wijffels, R H, De Goeij, A F P M, Cleutjens, J P M, Schutte, B

“…This study reveals the peculiar in vivo cell kinetics and cell turnover of the marine sponge Halisarca caerulea under steady-state conditions. The tropical…”
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Impaired cardiac functional reserve in type 2 diabetic db/db mice is associated with metabolic, but not structural, remodelling by Daniels, A, van Bilsen, M, Janssen, B.J.A, Brouns, A.E, Cleutjens, J.P.M, Roemen, T.H.M, Schaart, G, van der Velden, J, van der Vusse, G.J, van Nieuwenhoven, F.A

“…To identify the initial alterations in myocardial tissue associated with the early signs of diabetic cardiac haemodynamic dysfunction, we monitored changes in…”
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The relationship of peritubular capillary density with glomerular volume and kidney function in living kidney donors by van der Weijden, J., De Hoogt, P. A., Leufkens, M. M. E., Keijbeck, A. A., van Goor, H., van den Heuvel, M. C., Cleutjens, J. P. M., Moers, C., Snoeijs, M. G., Navis, G. J., van Londen, M., Nolte, I. M., Berger, S. P., De Borst, M. H., Peutz-Kootstra, C. J.

“…Background Peritubular capillary rarefaction plays an important role in the progression of chronic kidney disease. Little is known about the relation between…”
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Cardiac angiotensin converting enzyme and myocardial fibrosis in the rat by Sun, Y, Cleutjens, J P, Diaz-Arias, A A, Weber, K T

“…The aim was to test the hypothesis that cardiac angiotensin converting enzyme (ACE) is related to the accumulation of fibrous tissue in the heart. A model of…”
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Role of arginine in superficial wound healing in man by Debats, I.B.J.G., Wolfs, T.G.A.M., Gotoh, T., Cleutjens, J.P.M., Peutz-Kootstra, C.J., van der Hulst, R.R.W.J.

“…Arginine supplementation has been identified as advantageous in experimental wound healing. However, the mechanisms underlying this beneficial effect in tissue…”
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Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice by Blankesteijn, W. M., Creemers, E., Lutgens, E., Cleutjens, J. P. M., Daemen, M. J. A. P., Smits, J. F. M.

“…Recent improvements in the clinical management of acute myocardial infarction (MI) have resulted in a dramatic decrease in mortality because of this condition…”
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Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling by VOS, M. A, DE GROOT, S. H. M, WELLENS, H. J. J, VERDUYN, S. C, VAN DER ZANDE, J, LEUNISSEN, H. D. M, CLEUTJENS, J. P. M, VAN BILSEN, M, DAEMEN, M. J. A. P, SCHREUDER, J. J, ALLESSIE, M. A

“…Chronic, complete AV block (CAVB) in the dog leads to ventricular hypertrophy, which has been described as an independent risk factor for arrhythmias. In this…”
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Density is in the eye of the beholder: visual versus semi-automated assessment of breast density on standard mammograms by Lobbes, M. B. I., Cleutjens, J. P. M., Lima Passos, V., Frotscher, C., Lahaye, M. J., Keymeulen, K. B. M. I., Beets-Tan, R. G., Wildberger, J., Boetes, C.

“…Objectives Visual inspection is generally used to assess breast density. Our study aim was to compare visual assessment of breast density of experienced and…”
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Accelerated Atherosclerosis and Calcification in Vein Grafts: A Study in APOE3 Leiden Transgenic Mice by Lardenoye, J H.P, de Vries, M R, Löwik, C W.G.M, Xu, Q, Dhore, C R, Cleutjens, J P.M, van Hinsbergh, V W.M, van Bockel, J H, Quax, P H.A

“…ABSTRACT—Vein grafts fail due to development of intimal hyperplasia and accelerated atherosclerosis. Many murine genetic models in which genes are…”
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The infarcted myocardium : Simply dead tissue, or a lively target for therapeutic interventions by CLEUTJENS, J. P. M, BLANKESTEIJN, W. M, DAEMEN, M. J. A. P, SMITS, J. F. M

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Asynchronous electrical activation induces asymmetrical hypertrophy of the left ventricular wall by VAN OOSTERHOUT, M. F. M, PRINZEN, F. W, ARTS, T, SCHREUDER, J. J, VANAGT, W. Y. R, CLEUTJENS, J. P. M, RENEMAN, R. S

“…Asynchronous electrical activation, induced by ventricular pacing, causes regional differences in workload, which is lower in early- than in late-activated…”
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Collagen remodeling after myocardial infarction in the rat heart by Cleutjens, JP, Verluyten, MJ, Smiths, JF, Daemen, MJ

“…In this study changes in the amount and distribution of types I and III collagen mRNA and protein were investigated in the rat heart after induction of a left…”
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Expression of tenascin in perifollicular connective tissue : comparison of normal scalp and alopecia areata by VAN BAAR, H. M. J, PERRET, C. M, VAN VLIJMEN-WILLEMS, I. M. J. J, CLEUTJENS, J. P. M, MACKIE, E. J, HAPPLE, R, SCHALKWIJK, J

“…Tenascin, a recently discovered extracellular matrix protein, was demonstrated in perifollicular connective tissue of normal human scalp using…”
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The role of matrix metalloproteinases in heart disease by CLEUTJENS, J. P. M

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Absence of type IV collagen in the centre of the corneal epithelial basement membrane by Cleutjens, J P, Havenith, M G, Kasper, M, Vallinga, M, Bosman, F T

“…Type IV collagen is the basic structural component of all basement membranes (BM), and forms the backbone to which other BM components attach. We have found…”
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Human specific anti-type IV collagen monoclonal antibodies, characterization and immunohistochemical application by Havenith, M G, Cleutjens, J P, Beek, C, vd Linden, E, De Goeij, A F, Bosman, F T

“…This paper describes two new monoclonal antibodies reactive with human specific type IV collagen epitopes in frozen as well as routinely fixed and processed…”
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Monoclonal antibodies to native basement membranes reveal heterogeneous immunoreactivity patterns by Cleutjens, J P, Havenith, M G, Vallinga, M, Beek, C, Bosman, F T

“…In this paper we describe the development of basement membrane (BM) reactive monoclonal antibodies (MA), by immunization of mice with intact denuded BM. The MA…”
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Interstitial collagen is increased in the non-infarcted human myocardium after myocardial infarction by Volders, P G, Willems, I E, Cleutjens, J P, Arends, J W, Havenith, M G, Daemen, M J

“…In this study we report the changes of interstitial collagen in the human non-infarcted interventricular septum after a myocardial infarction as well as in…”
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Myocardial fibrosis in hypertensive heart disease: an overview of potential regulatory mechanisms by Weber, K T, Sun, Y, Guarda, E, Katwa, L C, Ratajska, A, Cleutjens, J P, Zhou, G

“…Myocardial fibrosis in hypertensive heart disease (HHD) can present as a reactive process, involving intramyocardial coronary arteries and arterioles with…”
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