Search Results - "Cleris, L."

TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells by Anania, M C, Sensi, M, Radaelli, E, Miranda, C, Vizioli, M G, Pagliardini, S, Favini, E, Cleris, L, Supino, R, Formelli, F, Borrello, M G, Pierotti, M A, Greco, A

“…Papillary thyroid carcinoma (PTC) arises from the thyroid follicular epithelium and represents the most frequent thyroid malignancy. PTC is associated with…”
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BIM upregulation and ROS-dependent necroptosis mediate the antitumor effects of the HDACi Givinostat and Sorafenib in Hodgkin lymphoma cell line xenografts by Locatelli, S L, Cleris, L, Stirparo, G G, Tartari, S, Saba, E, Pierdominici, M, Malorni, W, Carbone, A, Anichini, A, Carlo-Stella, C

“…Relapsed/refractory Hodgkin’s lymphoma (HL) is an unmet medical need requiring new therapeutic options. Interactions between the histone deacetylase inhibitor…”
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IGFBP7: an oncosuppressor gene in thyroid carcinogenesis by Vizioli, M G, Sensi, M, Miranda, C, Cleris, L, Formelli, F, Anania, M C, Pierotti, M A, Greco, A

“…Insulin-like growth factor-binding protein 7 (IGFBP7) is a secreted protein involved in several cellular processes, including proliferation, senescence and…”
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Perifosine and sorafenib combination induces mitochondrial cell death and antitumor effects in NOD/SCID mice with Hodgkin lymphoma cell line xenografts by Locatelli, S L, Giacomini, A, Guidetti, A, Cleris, L, Mortarini, R, Anichini, A, Gianni, A M, Carlo-Stella, C

“…The effects of the Akt inhibitor perifosine and the RAF/MEK/ERK inhibitor sorafenib were investigated using two CD30 + Hodgkin lymphoma cell lines (L-540 and…”
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Targeting COPZ1 in thyroid tumour cells by Anania, M.C, Cetti, E, Lecis, D, Cleris, L, Mazzoni, M, Pagliardini, S, Manenti, G, Greco, A

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174 Quantification of 3D Tumor Vessel Networks by Vessel Caliber, Amount and Distribution, Allows Comparison Among Effects of Vascular-targeted Therapies by Righi, M, Giacomini, A, Cleris, L, Gianni, A.M, Carlo-Stella, C

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48 Proffered Paper: The BH3-only Protein Bim Plays a Critical Role in Hodgkin Lymphoma Cell Death Triggered by the HDAC Inhibitor Givinostat and the Multikinase Inhibitor Sorafenib by Locatelli, S.L, Guidetti, A, Cleris, L, Gianni, A.M, Anichini, A, Carlo-Stella, C

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960 Combining Vascular Disruption Activity of TRAIL-expressing CD34+ Cells With Antiangiogenic Activity of Sorafenib Improves Regression of Tumor Growth by Giacomini, A, Lavazza, C, Grazia, G, Locatelli, S.L, Cleris, L, Righi, M, Gianni, A.M, Carlo-Stella, C

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Growth‐inhibitory effect of STI571 on cells transformed by the COL1A1/PDGFB rearrangement by Greco, A., Roccato, E., Miranda, C., Cleris, L., Formelli, F., Pierotti, M.A.

“…Dermatofibrosarcoma protuberans (DP) is a skin tumor of intermediate malignancy characterized by high recurrence rates, for which surgical excision is the main…”
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Therapeutic effects of the combination of fenretinide and all- trans-retinoic acid and of the two retinoids with cisplatin in a human ovarian carcinoma xenograft and in a cisplatin-resistant sub-line by Formelli, F, Cleris, L

“…We previously showed that fenretinide (4-HPR), a synthetic derivative of all- trans retinoic acid (RA), is effective in mice bearing the human ovarian…”
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Decrease in drug accumulation and in tumour aggressiveness marker expression in a fenretinide-induced resistant ovarian tumour cell line by APPIERTO, V, CAVADINI, E, PERGOLIZZI, R, CLERIS, L, LOTAN, R, CANEVARI, S, FORMELLI, F

“…We investigated whether the efficacy of fenretinide (HPR) against ovarian tumours may be limited by induction of resistance. The human ovarian carcinoma cell…”
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Effect of imatinib on haematopoietic recovery following idarubicin exposure by RUCHATZ, H, PUTTINI, M, CLERIS, L, PILOTTI, S, GAMBACORTI-PJSSERINI, C, FORMELLI, F

“…SCF is a potent pro-proliferative cytokine crucial for haematopoiesis, which binds to c-kit and activates its tyrosine kinase activity. Inactivating mutations…”
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236 (PB224): Tazemetostat and doxorubicin combined treatment in patient-derived preclinical models of epithelioid sarcoma by Soffientini, C., Arrighetti, N., Zuco, V., Cleris, L., Sigalotti, L., Maestro, R., Percio, S., Barisella, M., Collini, P., Dagrada, G.P., Frezza, A.M., Gronchi, A., Pasquali, S., Stacchiotti, S., Zaffaroni, N.

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Growth-inhibitory effect of STI571 on cells transformed by theCOL1A1/PDGFB rearrangement by Greco, A., Roccato, E., Miranda, C., Cleris, L., Formelli, F., Pierotti, M.A.

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439 - Targeting COPZ1 in thyroid tumour cells by Anania, M.C., Cetti, E., Lecis, D., Cleris, L., Mazzoni, M., Pagliardini, S., Manenti, G., Greco, A.

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Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells by Zuco, Valentina, Supino, Rosanna, Righetti, Sabina C, Cleris, Loredana, Marchesi, Edoardo, Gambacorti-Passerini, Carlo, Formelli, Franca

“…Betulinic acid is a triterpene with selective cytotoxicity against melanoma, neuroectodermal and malignant brain tumor cell lines. In this study the betulinic…”
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In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor by LE COUTRE, P, MOLOGNI, L, CLERIS, L, MARCHESI, E, BUCHDUNGER, E, GIARDINI, R, FORMELLI, F, GAMBACORTI-PASSERINI, C

“…The leukemia cells of approximately 95% of patients with chronic myeloid leukemia and 30%-50% of adult patients with acute lymphoblastic leukemia express the…”
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Verapamil potentiation of doxorubicin resistance development in B16 melanoma cells both in vitro and in vivo by FORMELLI, F, SUPINO, R, CLERIS, L, MARIANI, M

“…The effect of the combined administration of doxorubicin (DX) and verapamil (VRP) on the induction of DX resistance of B16 melanoma cells, was investigated…”
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Synthetic retinoid fenretinide is effective against a human ovarian carcinoma xenograft and potentiates cisplatin activity by FORMELLI, F, CLERIS, L

“…Fenretinide or N-(4-hydroxyphenyl) retinamide (4HPR) is a synthetic retinoid currently being tested clinically, which can inhibit the development and the…”
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The anti-human leukocyte antigen-DR monoclonal antibody 1D09C3 activates the mitochondrial cell death pathway and exerts a potent antitumor activity in lymphoma-bearing nonobese diabetic/ severe combined immunodeficient mice by CARLO-STELLA, Carmelo, DI NICOLA, Massimo, NAGY, Zoltan, GIOFFRE, Walter R, FORMELLI, Franca, GIANNI, Alessandro M, TURCO, Maria Caterina, CLERIS, Loredana, LAVAZZA, Cristiana, LONGONI, Paolo, MILANESI, Marco, MAGNI, Michele, AMMIRANTE, Massimo, LEONE, Arturo

“…The fully human anti-HLA-DR antibody 1D09C3 has been shown to delay lymphoma cell growth in severe combined immunodeficient (SCID) mice. The present study was…”
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