Search Results - "Clendaniel, Victoria"

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates by Musunuru, Kiran, Chadwick, Alexandra C., Mizoguchi, Taiji, Garcia, Sara P., DeNizio, Jamie E., Reiss, Caroline W., Wang, Kui, Iyer, Sowmya, Dutta, Chaitali, Clendaniel, Victoria, Amaonye, Michael, Beach, Aaron, Berth, Kathleen, Biswas, Souvik, Braun, Maurine C., Chen, Huei-Mei, Colace, Thomas V., Ganey, John D., Gangopadhyay, Soumyashree A., Garrity, Ryan, Kasiewicz, Lisa N., Lavoie, Jennifer, Madsen, James A., Matsumoto, Yuri, Mazzola, Anne Marie, Nasrullah, Yusuf S., Nneji, Joseph, Ren, Huilan, Sanjeev, Athul, Shay, Madeleine, Stahley, Mary R., Fan, Steven H. Y., Tam, Ying K., Gaudelli, Nicole M., Ciaramella, Giuseppe, Stolz, Leslie E., Malyala, Padma, Cheng, Christopher J., Rajeev, Kallanthottathil G., Rohde, Ellen, Bellinger, Andrew M., Kathiresan, Sekar

“…Gene-editing technologies, which include the CRISPR–Cas nucleases 1 – 3 and CRISPR base editors 4 , 5 , have the potential to permanently modify…”
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Histone Deacetylase 3 Inhibition Decreases Cerebral Edema and Protects the Blood-Brain Barrier after Stroke (S33.001) by Lu, Hui, Lin, Chin, Clendaniel, Victoria, Matheson, Rudy, Fisher, Marc, Lo, Eng, Selim, Magdy, Shehadah, Amjad

“…Abstract only…”
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Abstract TP272: Selective Inhibition of Histone Deacetylase 3 Decreases Cerebral Edema and Blood-Brain Barrier Leakage by Shehadah, Amjad, Lu, Hui, Clendaniel, Victoria, Matheson, Rudy, Fisher, Marc, Selim, Magdy, Lo, Eng

“…Abstract only Introduction: Histone deacetylase 3 (HDAC3) has been implicated as neurotoxic in several neurodegenerative conditions. However, its role in…”
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Histone Deacetylase 3 Inhibition Decreases Cerebral Edema and Protects the Blood–Brain Barrier After Stroke by Lu, Hui, Ashiqueali, Ryan, Lin, Chin I, Walchale, Aashlesha, Clendaniel, Victoria, Matheson, Rudy, Fisher, Marc, Lo, Eng H., Selim, Magdy, Shehadah, Amjad

“…We have previously shown that selective inhibition of histone deacetylase 3 (HDAC3) decreases infarct volume and improves long-term functional outcomes after…”
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An investigational in vivo base editing medicine targeting ANGPTL3, VERVE-201, achieves precise and durable liver editing in nonclinical studies by Lee, Richard, Mazzola, Anne, Denizio, Jamie, Mizoguchi, Taiji, Clendaniel, Victoria, Garrity, Ryan, Cox, Nicholas, Glass, Zachary, Chamarthi, Hareesh, Flannigan, Sydney, Matsumoto, Yuri, Braun, Maurine, Kathiresan, Sekar, Biedenkapp, Joseph, Rohde, Ellen, Bellinger, Andrew, Khera, Amit

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Neuroprotective Effects of Selective Inhibition of Histone Deacetylase 3 in Experimental Stroke by Matheson, Rudy, Chida, Kohei, Lu, Hui, Clendaniel, Victoria, Fisher, Marc, Thomas, Ajith, Lo, Eng H., Selim, Magdy, Shehadah, Amjad

“…Histone deacetylase 3 (HDAC3) has been implicated as neurotoxic in several neurodegenerative conditions. However, the role of HDAC3 in ischemic stroke has not…”
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