Search Results - "Clemmings, Sue M"

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope by Chen, Yahua, Ricordi, Camillo, Clemmings, Sue M, Hafler, David A, Hering, Bernhard J, Kenyon, Norma Sue, Kent, Sally C, Bregoli, Lisa

“…In autoimmune type 1 diabetes, pathogenic T lymphocytes are associated with the specific destruction of insulin-producing β-islet cells. Identification of the…”
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Transplantation of Cultured Islets from Two‐Layer Preserved Pancreases in Type 1 Diabetes with Anti‐CD3 Antibody by Hering, Bernhard J., Kandaswamy, Raja, Harmon, James V., Ansite, Jeffrey D., Clemmings, Sue M., Sakai, Tetsuya, Paraskevas, Stephen, Eckman, Peter M., Sageshima, Junichiro, Nakano, Masahiko, Sawada, Toshiya, Matsumoto, Ippei, Zhang, Hui J., Sutherland, David E. R., Bluestone, Jeffrey A.

“…We sought to determine whether or not optimizing pancreas preservation, islet processing, and induction immunosuppression would facilitate sustained diabetes…”
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Loss of IL-4 Secretion from Human Type 1a Diabetic Pancreatic Draining Lymph Node NKT Cells by Kent, Sally C, Chen, Yahua, Clemmings, Sue M, Viglietta, Vissia, Kenyon, Norma Sue, Ricordi, Camillo, Hering, Bernhard, Hafler, David A

“…Altered frequency and function of peripheral invariant NKT (iNKT) cells have been implicated in the regulation of murine and human type 1a diabetes. To examine…”
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Reversal of diabetes in non-immunosuppressed rhesus macaques by intraportal porcine islet xenografts precedes acute cellular rejection by Kirchhof, Nicole, Shibata, Satoshi, Wijkstrom, Martin, Kulick, David M., Salerno, Christopher T., Clemmings, Sue M., Heremans, Yves, Galili, Uri, Sutherland, David E.R., Dalmasso, Agustin P., Hering, Bernhard J.

“…:  Background:  The functional response and immunobiology of primarily non‐vascularized islet cell xenografts remain poorly defined in non‐human primates…”
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Immunology Insulin auto-antigenicity in type 1 diabetes (Reply) by Hafler, David A, Kent, Sally C, Chen, Yahua, Bregoli, Lisa, Clemmings, Sue M, Hering, Bernhard, Kenyon, Norma Sue, Ricordi, Camillo

“…Wilson discusses the avidity of the lymph-node T-cell clones we described that recognize the insulin A1-15 fragment. He questions whether large enough…”
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Insulin auto-antigenicity in type 1 diabetes (Reply) by Hafler, David A, Kent, Sally C, Chen, Yahua, Bregoli, Lisa, Clemmings, Sue M, Hering, Bernhard, Kenyon, Norma Sue

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Total lymphoid irradiation, without intrathymic injection of donor cells, induces indefinite acceptance of heart but not islet or skin allografts in rats by Papalois, B E, Wahoff, D C, Aasheim, T C, Griffin, R J, Jessurun, J, Clemmings, S M, Field, J M, Leone, J P, Sutherland, D E

“…Allograft tolerance occurs in rodents given a dose of antilymphocyte serum (ALS) and intrathymic injection (ITI) of donor splenocytes (SC) 1-3 weeks prior to…”
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