Search Results - "Clement, P."

A bioavailable strontium isoscape for Western Europe: A machine learning approach by Bataille, Clement P, von Holstein, Isabella C C, Laffoon, Jason E, Willmes, Malte, Liu, Xiao-Ming, Davies, Gareth R

“…Strontium isotope ratios (87Sr/86Sr) are gaining considerable interest as a geolocation tool and are now widely applied in archaeology, ecology, and forensic…”
Get full text

Durvalumab with or without tremelimumab in patients with recurrent or metastatic head and neck squamous cell carcinoma: EAGLE, a randomized, open-label phase III study by Ferris, R.L., Haddad, R., Even, C., Tahara, M., Dvorkin, M., Ciuleanu, T.E., Clement, P.M., Mesia, R., Kutukova, S., Zholudeva, L., Daste, A., Caballero-Daroqui, J., Keam, B., Vynnychenko, I., Lafond, C., Shetty, J., Mann, H., Fan, J., Wildsmith, S., Morsli, N., Fayette, J., Licitra, L.

“…Targeting the programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) axis has demonstrated clinical benefit in recurrent/metastatic head…”
Get full text

SYNGAP1: Mind the Gap by Jeyabalan, Nallathambi, Clement, James P

“…A cardinal feature of early stages of human brain development centers on the sensory, cognitive, and emotional experiences that shape neuronal-circuit…”
Get full text

Tectonic controls on the isotopic juvenility of mid-Cretaceous continental arcs: Global compilations and implications for chemical weathering by Cao, Wenrong, Bataille, Clément P., Leuchter, Ethan R., Zhou, Xiqiang

“…Continental arcs influence the global carbon cycle via degassing and chemical weathering. Several studies also suggested that the isotopic composition of…”
Get full text

Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses by Clement, James P., Aceti, Massimiliano, Creson, Thomas K., Ozkan, Emin D., Shi, Yulin, Reish, Nicholas J., Almonte, Antoine G., Miller, Brooke H., Wiltgen, Brian J., Miller, Courtney A., Xu, Xiangmin, Rumbaugh, Gavin

“…Mutations that cause intellectual disability (ID) and autism spectrum disorder (ASD) are commonly found in genes that encode for synaptic proteins. However, it…”
Get full text

A randomized, phase II study of afatinib versus cetuximab in metastatic or recurrent squamous cell carcinoma of the head and neck by Seiwert, T.Y., Fayette, J., Cupissol, D., del Campo, J.M., Clement, P.M., Hitt, R., Degardin, M., Zhang, W., Blackman, A., Ehrnrooth, E., Cohen, E.E.W.

“…Afatinib is an oral, irreversible ErbB family blocker that has shown activity in epidermal growth factor receptor (EGFR)-mutated lung cancer. We hypothesized…”
Get full text

Mechanical characterization of highly porous inorganic solids materials by instrumented micro-indentation by Clément, P., Meille, S., Chevalier, J., Olagnon, C.

“…This study focuses on the mechanical characterization of highly porous inorganic solids through spherical micro-indentation. The mechanical properties of a…”
Get full text

Epilepsy Characteristics in Neurodevelopmental Disorders: Research from Patient Cohorts and Animal Models Focusing on Autism Spectrum Disorder by Chakraborty, Sukanya, Parayil, Rrejusha, Mishra, Shefali, Nongthomba, Upendra, Clement, James P.

“…Epilepsy, a heterogeneous group of brain-related diseases, has continued to significantly burden society and families. Epilepsy comorbid with…”
Get full text

TNF differentially regulates ganglioside biosynthesis and expression in breast cancer cell lines by Dewald, Justine H, Cavdarli, Sumeyye, Steenackers, Agata, Delannoy, Clément P, Mortuaire, Marlène, Spriet, Corentin, Noël, Maxence, Groux-Degroote, Sophie, Delannoy, Philippe

“…Gangliosides are glycosphingolipids concentrated in glycolipid-enriched membrane microdomains. Mainly restricted to the nervous system in healthy adult,…”
Get full text

Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus by Sorin, Marie N., Di Maio, Antonio, Silva, Lisete M., Ebert, Domenic, Delannoy, Clément P., Nguyen, Ngoc-Khanh, Guerardel, Yann, Chai, Wengang, Halary, Franck, Renaudin-Autain, Karine, Liu, Yan, Bressollette-Bodin, Céline, Stehle, Thilo, McIlroy, Dorian

“…BK polyomavirus (BKPyV) is an opportunistic pathogen that uses the b-series gangliosides GD1b and GT1b as entry receptors. Here, we characterize the impact of…”
Get full text

Hydrogeological controls on spatial patterns of groundwater discharge in peatlands by Hare, Danielle K, Boutt, David F, Clement, William P, Hatch, Christine E, Davenport, Glorianna, Hackman, Alex

“…Peatland environments provide important ecosystem services including water and carbon storage, nutrient processing and retention, and wildlife habitat…”
Get full text

Assessing geographic controls of hair isotopic variability in human populations: A case-study in Canada by Bataille, Clement P, Chartrand, Michelle M. G, Raposo, Francis, St-Jean, Gilles, Drucker, Dorothée

“…Studying the isotope variability in fast-growing human tissues (e.g., hair, nails) is a powerful tool to investigate human nutrition. However, interpreting the…”
Get full text

Systems biology approach for enhancing limonene yield by re-engineering Escherichia coli by Khanijou, Jasmeet Kaur, Hee, Yan Ting, Scipion, Clement P. M., Chen, Xixian, Selvarajoo, Kumar

“…Engineered microorganisms have emerged as viable alternatives for limonene production. However, issues such as low enzyme abundance or activities, and…”
Get full text

Does primary colonization or community structure determine the succession of fouling communities? by Cifuentes, Mauricio, Krueger, Ina, Dumont, Clément P., Lenz, Mark, Thiel, Martin

“…Predicting the relevance of initial colonization and subsequent species interactions for succession in marine sessile communities is difficult because the…”
Get full text

Controls of lithium isotope spatial variability across the Yukon River: Implications for weathering processes in a warming subarctic basin by Kang, Myunghak, Skierszkan, Elliott, Brennan, Sean, Fernandez, Diego P., Yang, Zhaoping, Girard, Isabelle, Gammon, Paul, de Laplante, Ghislain, Bataille, Clément P.

“…[Display omitted] With ongoing global warming and permafrost thawing, weathering processes will change on the Yukon River, with risks for water quality and…”
Get full text

Iron oxide and oxygen plasma functionalized multi-walled carbon nanotubes for the discrimination of volatile organic compounds by CLEMENT, P, HAFAIEDH, I, PARRA, E. J, THAMRI, A, GUILLOT, J, ABDELGHANI, A, LLOBET, E

“…Oxygen plasma functionalized multiwall carbon nanotubes and iron oxide decorated multiwall carbon nanotubes are studied for detecting volatile organic…”
Get full text

Incidence of medication-related osteonecrosis of the jaw in patients treated with both bone resorption inhibitors and vascular endothelial growth factor receptor tyrosine kinase inhibitors by van Cann, T., Loyson, T., Verbiest, A., Clement, P. M., Bechter, O., Willems, L., Spriet, I., Coropciuc, R., Politis, C., Vandeweyer, R. O., Schoenaers, J., Debruyne, P. R., Dumez, H., Berteloot, P., Neven, P., Nackaerts, K., Woei-A-Jin, F. J. S. H., Punie, K., Wildiers, H., Beuselinck, B.

“…Background Several case reports and small case series have suggested a higher incidence of medication-related osteonecrosis of the jaw (MRONJ) in patients…”
Get full text

Structural evidence for the roles of divalent cations in actin polymerization and activation of ATP hydrolysis by Scipion, Clement P. M., Ghoshdastider, Umesh, Ferrer, Fernando J., Yuen, Tsz-Ying, Wongsantichon, Jantana, Robinson, Robert C.

“…The structure of the actin filament is known at a resolution that has allowed the architecture of protein components to be unambiguously assigned. However,…”
Get full text

Direct brain projections onto the spinal generator of ejaculation in the rat by Facchinetti, P, Giuliano, F, Laurin, M, Bernabé, J, Clément, P

“…Highlights • The spinal generator for ejaculation (SGE) receives direct projections from the brain. • Projecting neurons are located in nuclei of medulla…”
Get full text

Harmonizing and Extending Fragmented 100 Year Flood Hazard Maps in Canada’s Capital Region Using Random Forest Classification by Bhuiyan, Shelina A., Bataille, Clement P., McGrath, Heather

“…With the record breaking flood experienced in Canada’s capital region in 2017 and 2019, there is an urgent need to update and harmonize existing flood hazard…”
Get full text