Search Results - "Clement, MJ"

Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: an open-label, randomised phase 3 trial by Machiels, Jean-Pascal, Prof, Subramanian, Somasundaram, MD, Ruzsa, Agnes, MD, Repassy, Gabor, Prof, Lifirenko, Igor, MD, Flygare, Annika, BSc, Sørensen, Per, MSc, Nielsen, Tina, MD, Lisby, Steen, MD, Clement, Paul MJ, PhD

“…Summary Background No treatments are presently available to increase survival in patients with recurrent or metastatic squamous-cell carcinoma of the head and…”
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Pathoscope: species identification and strain attribution with unassembled sequencing data by Francis, Owen E, Bendall, Matthew, Manimaran, Solaiappan, Hong, Changjin, Clement, Nathan L, Castro-Nallar, Eduardo, Snell, Quinn, Schaalje, G Bruce, Clement, Mark J, Crandall, Keith A, Johnson, W Evan

“…Emerging next-generation sequencing technologies have revolutionized the collection of genomic data for applications in bioforensics, biosurveillance, and for…”
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Rhizobial Plasmids That Cause Impaired Symbiotic Nitrogen Fixation and Enhanced Host Invasion by CROOK, Matthew B, LINDSAY, Daniel P, BIGGS, Matthew B, BENTLEY, Joshua S, PRICE, Jared C, CLEMENT, Spencer C, CLEMENT, Mark J, LONG, Sharon R, GRIFFITTS, Joel S

“…The genetic rules that dictate legume-rhizobium compatibility have been investigated for decades, but the causes of incompatibility occurring at late stages of…”
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Multiple hyperplastic polyps in the stomach: Evidence for clonality and neoplastic potential by Dijkhuizen, SM, Entius, MM, Clement, MJ, Polak, MM, Van den Berg, FM, Craanen, ME, Slebos, RJ, Offerhaus, GJ

“…The origin and neoplastic potential of gastric epithelial polyps remains an area of great interest, and treatment choices are a topic of controversy. This…”
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Toward a better understanding of the basis of the molecular mimicry of polysaccharide antigens by peptides: the example of Shigella flexneri 5a by Clément, Marie-Jeanne, Fortuné, Antoine, Phalipon, Armelle, Marcel-Peyre, Véronique, Simenel, Catherine, Imberty, Anne, Delepierre, Muriel, Mulard, Laurence A

“…Protein conjugates of oligosaccharides or peptides that mimic complex bacterial polysaccharide antigens represent alternatives to the classical…”
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N-Terminal Stathmin-like Peptides Bind Tubulin and Impede Microtubule Assembly by Clément, Marie-Jeanne, Jourdain, Isabelle, Lachkar, Sylvie, Savarin, Philippe, Gigant, Benoît, Knossow, Marcel, Toma, Flavio, Sobel, André, Curmi, Patrick A

“…Microtubules are major cytoskeletal components involved in numerous cellular functions such as mitosis, cell motility, or intracellular traffic. These…”
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Conformational Studies of the O-specific Polysaccharide of Shigella flexneri 5a and of Four Related Synthetic Pentasaccharide Fragments Using NMR and Molecular Modeling by Clément, Marie-Jeanne, Imberty, Anne, Phalipon, Armelle, Pérez, Serge, Simenel, Catherine, Mulard, Laurence A, Delepierre, Muriel

“…As part of a program for the development of synthetic vaccines against the pathogen Shigella flexneri , we used a combination of NMR and molecular modeling…”
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Impact of depatuxizumab mafodotin on health-related quality of life and neurological functioning in the phase II EORTC 1410/INTELLANCE 2 trial for EGFR-amplified recurrent glioblastoma by Clement, Paul M.J., Dirven, Linda, Eoli, Marica, Sepulveda-Sanchez, Juan M., Walenkamp, Annemiek M.E., Frenel, Jean S., Franceschi, Enrico, Weller, Michael, Chinot, Olivier, De Vos, Filip Y.F.L., Whenham, Nicolas, Sanghera, Paul, Looman, Jim, Kundu, Madan G., Peter de Geus, Jan, Nuyens, Sarah, Spruyt, Maarten, Gorlia, Thierry, Coens, Corneel, Golfinopoulos, Vassilis, Reijneveld, Jaap C., van den Bent, Martin J.

“…In the EORTC 1410/INTELLANCE 2 randomised, phase II study (NCT02343406), with the antibody–drug conjugate depatuxizumab mafodotin (Depatux-M, ABT-414) in…”
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Synthesis and NMR study of a linear pentasaccharide fragment of the Shigella flexneri 5a O-specific polysaccharide by Mulard, Laurence A, Clément, Marie-Jeanne, Segat-Dioury, Fabienne, Delepierre, Muriel

“…A convergent chemical synthesis of the methyl glycoside of the linear epitope α- d-Glc p-(1→3)-α- l-Rha p-(1→3)-α- l-Rha p-(1→3)-β- d-GlcNAc p-(1→2)-α- l-Rha p…”
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Templated polycondensation of aminopropyltrimethoxysilane on DNA by Jarroux, N., Clément, M.J., Gervais, M., Moriau, S., Maciejak, O., Curmi, P.A., Cheradame, H.

“…•Polycondensation of ATMS in the presence of DNA in chloroform is a template reaction.•Faster reactions in the presence of adenosine group demonstrate…”
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Convergent Synthesis, NMR and Conformational Analysis of Tetra- and Pentasaccharide Haptens of the Shigella flexneri Serotype 5a O-Specific Polysaccharide by Mulard, Laurence A., Clément, Marie-Jeanne, Imberty, Anne, Delepierre, Muriel

“…Convergent syntheses of the methyl glycosides of the branched pentasaccharide α‐L‐Rhap‐(1⇄2)‐[α‐D‐Glcp(1⇄3)]‐α‐L‐Rhap‐(1⇄3)‐α‐L‐Rhap‐(1⇄3)‐β‐D‐GlcNAcp…”
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Detection of K-ras mutations in mucinous pancreatic duct hyperplasia from a patient with a family history of pancreatic carcinoma by DiGiuseppe, JA, Hruban, RH, Offerhaus, GJ, Clement, MJ, van den Berg, FM, Cameron, JL, van Mansfeld, AD

“…Mutations in the K-ras oncogene and in the p53 tumor suppressor gene are commonly identified in sporadic cases of pancreatic adenocarcinoma. Although these…”
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p53 alterations in atypical alveolar hyperplasia of the human lung by Slebos, Robbert J.C, Baas, Inge O, Clement, Marjon J, Offerhaus, G.Johan A, Askin, Fredric B, Hruban, Ralph H, Westra, William H

“…Atypical alveolar hyperplasia (AAH) is a potential precursor lesion from which lung adenocarcinomas arise and may be a good target for studying the early…”
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Alterations of the p53 tumor‐suppressor gene and K‐ ras oncogene in perihilar cholangiocarcinomas from a high‐incidence area by Sturm, Patrick D. J., Baas, Inge O., Clement, Marjon J., Nakeeb, Attila, Offerhaus, G. Johan A., Hruban, Ralph H., Pitt, Henry A.

“…We observed a clustering of cholangiocarcinoma in a part of West Virginia. We analyzed the frequency and type of alterations in the p53 tumor‐suppressor gene…”
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POTENTIAL FALSE-POSITIVE RESULTS WITH ANTIGEN ENHANCEMENT FOR IMMUNOHISTOCHEMISTRY OF THE p53 GENE PRODUCT IN COLORECTAL NEOPLASMS by BAAS, INGE O., VAN DEN BERG, FRANK M., MULDER, JAN-WILLEM R., CLEMENT, MARJON J., SLEBOS, ROBBERT J. C., HAMILTON, STANLEY R., OFFERHAUS, G. JOHAN A.

“…Aberrant crypt foci (ACF) are putative precursor lesions of colon cancer, recently identified on the methylene blue‐stained mucosal surface of human colon. No…”
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Molecular evidence of field cancerization in a patient with 7 tumors of the aerodigestive tract by van Rees, Bastiaan P., Cleton-Jansen, Anne-Marie, Cense, Huib A., Polak, Mirjam M., Clement, Marjon J., Drillenburg, Paul, van Lanschot, Jan J.B., Offerhaus, G. Johan A.

“…Exposure of the mucosa of the upper aerodigestive tract to carcinogens can induce genetic changes resulting in various independent clones of neoplastic growth,…”
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Sensitivity of Treponemal Tests for Detecting Prior Treated Syphilis during Human Immunodeficiency Virus Infection by Haas, Jennifer S., Bolan, Gail, Larsen, Sandra A., Clement, Michael J., Bacchetti, Peter, Moss, Andrew R.

“…To evaluate the sensitivity of treponemal tests as a marker of prior syphilis in individuals with human immunodeficiency virus (HIV) infection, the syphilis…”
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Extrapulmonary pneumocystosis: clinical features in human immunodeficiency virus infection by Northfelt, D W, Clement, M J, Safrin, S

“…Pneumocystis carinii infection is reported with increasing frequency as a cause of disease outside of the respiratory tract in patients with human…”
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Automated performance prediction for scalable parallel computing by Clement, Mark J., Quinn, Michael J.

“…Performance prediction is necessary in order to deal with multi-dimensional performance effects on parallel systems. The compiler-generated analytical model…”
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A survey of adolescents with epilepsy by Clement, M J, Wallace, S J

“…Thirty-four adolescents with epilepsy, controls matched for age and sex (A) and controls matched for age, sex and general ability (B), were studied. The…”
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