Search Results - "Cleary, Megan M"

EphB4/EphrinB2 therapeutics in Rhabdomyosarcoma by Randolph, Matthew E, Cleary, Megan M, Bajwa, Zia, Svalina, Matthew N, Young, Michael C, Mansoor, Atiya, Kaur, Pali, Bult, Carol J, Goros, Martin W, Michalek, Joel E, Xiang, Sunny, Keck, James, Krasnoperov, Valery, Gill, Parkash, Keller, Charles

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma affecting children and is often diagnosed with concurrent metastases. Unfortunately, few…”
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Defining the Extracellular Matrix of Rhabdomyosarcoma by Lian, Xiaolei, Bond, J Steffan, Bharathy, Narendra, Boudko, Sergei P, Pokidysheva, Elena, Shern, Jack F, Lathara, Melvin, Sasaki, Takako, Settelmeyer, Teagan, Cleary, Megan M, Bajwa, Ayeza, Srinivasa, Ganapati, Hartley, Christopher P, Bächinger, Hans Peter, Mansoor, Atiya, Gultekin, Sakir H, Berlow, Noah E, Keller, Charles

“…Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood with a propensity to metastasize. Current treatment for patients with RMS includes…”
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NFκB signaling in alveolar rhabdomyosarcoma by Cleary, Megan M, Mansoor, Atiya, Settelmeyer, Teagan, Ijiri, Yuichi, Ladner, Katherine J, Svalina, Matthew N, Rubin, Brian P, Guttridge, Denis C, Keller, Charles

“…Alveolar rhabdomyosarcoma (aRMS) is a pediatric soft tissue cancer commonly associated with a chromosomal translocation that leads to the expression of a…”
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Sensitization of osteosarcoma to irradiation by targeting nuclear FGFR1 by Kim, Jin-Ah, Berlow, Noah E., Lathara, Melvin, Bharathy, Narendra, Martin, Leah R., Purohit, Reshma, Cleary, Megan M., Liu, Qianqian, Michalek, Joel E., Srinivasa, Ganapati, Cole, Bonnie L., Chen, Sonja D., Keller, Charles

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Interleukin-4 Receptor Inhibition Targeting Metastasis Independent of Macrophages by Cleary, Megan M, Bharathy, Narendra, Abraham, Jinu, Kim, Jin-Ah, Rudzinski, Erin R, Michalek, Joel E, Keller, Charles

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma occurring in children and carries a dismal prognosis when metastatic disease is detected. Our…”
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SMARCA4 biology in alveolar rhabdomyosarcoma by Bharathy, Narendra, Cleary, Megan M., Kim, Jin-Ah, Nagamori, Kiyo, Crawford, Kenneth A., Wang, Eric, Saha, Debarya, Settelmeyer, Teagan P., Purohit, Reshma, Skopelitis, Damianos, Chang, Kenneth, Doran, Jessica A., Kirschbaum, C. Ward, Bharathy, Suriya, Crews, Davis W., Randolph, Matthew E., Karnezis, Anthony N., Hudson-Price, Lisa, Dhawan, Jyotsna, Michalek, Joel E., Ciulli, Alessio, Vakoc, Christopher R., Keller, Charles

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and phenocopies a muscle precursor that fails to undergo terminal differentiation…”
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In vitro benchmarking of NF-κB inhibitors by Harrold, Alexandria P., Cleary, Megan M., Bharathy, Narendra, Lathara, Melvin, Berlow, Noah E., Foreman, Nicholas K., Donson, Andrew M., Amani, Vladimir, Zuercher, William J., Keller, Charles

“…Dysregulated activity of the transcription factors of the nuclear factor κb (NF-κB) family has been implicated in numerous cancer types, inflammatory diseases,…”
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Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia by Richard, Nameeta P, Pippa, Raffaella, Cleary, Megan M, Puri, Alka, Tibbitts, Deanne, Mahmood, Shawn, Christensen, Dale J, Jeng, Sophia, McWeeney, Shannon, Look, A Thomas, Chang, Bill H, Tyner, Jeffrey W, Vitek, Michael P, Odero, María D, Sears, Rosalie, Agarwal, Anupriya

“…Recent evidence suggests that inhibition of protein phosphatase 2A (PP2A) tumor suppressor activity via the SET oncoprotein contributes to the pathogenesis of…”
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Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma by Bharathy, Narendra, Svalina, Matthew N, Settelmeyer, Teagan P, Cleary, Megan M, Berlow, Noah E, Airhart, Susan D, Xiang, Sunny, Keck, James, Hayden, James B, Shern, Jack F, Mansoor, Atiya, Lathara, Melvin, Srinivasa, Ganapati, Langenau, David M, Keller, Charles

“…Rhabdomyosarcoma (RMS) is the most common childhood soft tissue sarcoma. RMS often arise from myogenic precursors and displays a poorly differentiated skeletal…”
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p38MAPK Inhibition Blocks Inflammatory Signaling in Acute Myeloid Leukemia by Carey, Alyssa, Garg, Swati, Cleary, Megan M, Edwards, David K, Loriaux, Marc, Winski, Shannon L, Cable, LouAnn, Tyner, Jeffrey W., Agarwal, Anupriya

“…Background: p38 mitogen-activated protein kinase (p38MAPK) is activated by various pro-inflammatory and stress-related stimuli, and has been an attractive…”
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Pacritinib, a Dual FLT3/JAK2 Inhibitor, Reduces Irak-1 Signaling in Acute Myeloid Leukemia by Cleary, Megan M, Thompson, Rhese, Mahmood, Shawn, Davare, Monika, Kurtz, Steve, Elferich, Johannes, Shinde, Ujwal, Druker, Brian J., Singer, Jack, Agarwal, Anupriya

“…Background: A momentous challenge in the treatment of acute myeloid leukemia (AML) is the significant molecular heterogeneity in driving abnormalities and…”
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The Pro-Inflammatory Cytokine Interleukin-1 Is Essential for Clonal Expansion and Disease Progression in Acute Myeloid Leukemia by Carey, Alyssa, Cleary, Megan M, Edwards, David K, Eide, Christopher A., Traer, Elie, McWeeney, Shannon K., Tyner, Jeffrey W., Bagby, Grover C., Druker, Brian J., Agarwal, Anupriya

“…Background: Recent 'omics'-based approaches have revealed that acute myeloid leukemia (AML) has significant genetic heterogeneity, and that clonal evolution in…”
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