Search Results - "Clear, Kasey J."

Imaging and therapeutic applications of zinc(ii)-dipicolylamine molecular probes for anionic biomembranes by Rice, Douglas R, Clear, Kasey J, Smith, Bradley D

“…This feature article describes the development of synthetic zinc(ii)-dipicolylamine (ZnDPA) receptors as selective targeting agents for anionic membranes in…”
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Redox and Nucleophilic Reactions of Naphthoquinones with Small Thiols and Their Effects on Oxidization of H2S to Inorganic and Organic Hydropolysulfides and Thiosulfate by Olson, Kenneth R., Clear, Kasey J., Gao, Yan, Ma, Zhilin, Cieplik, Nathaniel M., Fiume, Alyssa R., Gaziano, Dominic J., Kasko, Stephen M., Luu, Jennifer, Pfaff, Ella, Travlos, Anthony, Velander, Cecilia, Wilson, Katherine J., Edwards, Elizabeth D., Straub, Karl D., Wu, Gang

“…Naphthoquinone (1,4-NQ) and its derivatives (NQs, juglone, plumbagin, 2-methoxy-1,4-NQ, and menadione) have a variety of therapeutic applications, many of…”
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Naphthoquinones Oxidize H2S to Polysulfides and Thiosulfate, Implications for Therapeutic Applications by Olson, Kenneth R., Clear, Kasey J., Derry, Paul J., Gao, Yan, Ma, Zhilin, Cieplik, Nathaniel M., Fiume, Alyssa, Gaziano, Dominic J., Kasko, Stephen M., Narloch, Kathleen, Velander, Cecilia L., Nwebube, Ifeyinwa, Pallissery, Collin J., Pfaff, Ella, Villa, Brian P., Kent, Thomas A., Wu, Gang, Straub, Karl D.

“…1,4-Napththoquinones (NQs) are clinically relevant therapeutics that affect cell function through production of reactive oxygen species (ROS) and formation of…”
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The SOD1 Inhibitor, LCS-1, Oxidizes H2S to Reactive Sulfur Species, Directly and Indirectly, through Conversion of SOD1 to an Oxidase by Olson, Kenneth R, Takata, Tsuyoshi, Clear, Kasey J, Gao, Yan, Ma, Zhilin, Pfaff, Ella, Mouli, Karthik, Kent, Thomas A, Jones, Jr, Prentiss, Fukuto, Jon, Wu, Gang, Straub, Karl D

“…LCS-1, a putative selective inhibitor of SOD1, is a substituted pyridazinone with rudimentary similarity to quinones and naphthoquinones. As quinones…”
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Reaction Mechanisms of H2S Oxidation by Naphthoquinones by Olson, Kenneth R., Clear, Kasey J., Takata, Tsuyoshi, Gao, Yan, Ma, Zhilin, Pfaff, Ella, Travlos, Anthony, Luu, Jennifer, Wilson, Katherine, Joseph, Zachary, Kyle, Ian, Kasko, Stephen M., Jones Jr, Prentiss, Fukuto, Jon, Xian, Ming, Wu, Gang, Straub, Karl D.

“…1,4-naphthoquinones (NQs) catalytically oxidize H2S to per- and polysufides and sulfoxides, reduce oxygen to superoxide and hydrogen peroxide, and can form…”
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Coenzyme Q10 and related quinones oxidize H2S to polysulfides and thiosulfate by Olson, Kenneth R., Clear, Kasey J., Derry, Paul J., Gao, Yan, Ma, Zhilin, Wu, Gang, Kent, Thomas A., Straub, Karl D.

“…In the canonical pathway for mitochondrial H2S oxidation electrons are transferred from sulfide:quinone oxidoreductase (SQR) to complex III via ubiquinone…”
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Dual colorimetric and luminescent assay for dipicolinate, a biomarker of bacterial spores by Clear, Kasey J, Stroud, Sarah, Smith, Bradley D

“…A binary mixture of Tb(3+) and pyrocatechol violet (PV) forms a 1 : 1 Tb(3+)/PV complex that can be used in a dye displacement assay. Addition of dipicolinate…”
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F NMR indicator displacement assay using a synthetic receptor with appended paramagnetic relaxation agent by Plaunt, Adam J, Clear, Kasey J, Smith, Bradley D

“…An admixture of zinc(II)-bis(dipicolylamine) receptor with covalently attached paramagnetic relaxation agent and fluorine-labeled phosphate indicator enables…”
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Phenoxide-Bridged Zinc(II)-Bis(dipicolylamine) Probes for Molecular Imaging of Cell Death by Clear, Kasey J, Harmatys, Kara M, Rice, Douglas R, Wolter, William R, Suckow, Mark A, Wang, Yuzhen, Rusckowski, Mary, Smith, Bradley D

“…Cell death is involved in many pathological conditions, and there is a need for clinical and preclinical imaging agents that can target and report cell death…”
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Small molecule additive enhances cell uptake of 5-aminolevulinic acid and conversion to protoporphyrin IX by Harmatys, Kara M, Musso, Anthony J, Clear, Kasey J, Smith, Bradley D

“…Administration of exogenous 5-aminolevulinic acid (5-ALA) to cancerous tissue leads to intracellular production of photoactive protoporphyrin IX, a…”
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Redox and Nucleophilic Reactions of Naphthoquinones with Small Thiols and Their Effects on Oxidization of H[sub.2]S to Inorganic and Organic Hydropolysulfides and Thiosulfate by Olson, Kenneth R, Clear, Kasey J, Gao, Yan, Ma, Zhilin, Cieplik, Nathaniel M, Fiume, Alyssa R, Gaziano, Dominic J, Kasko, Stephen M, Luu, Jennifer, Pfaff, Ella, Travlos, Anthony, Velander, Cecilia, Wilson, Katherine J, Edwards, Elizabeth D, Straub, Karl D, Wu, Gang

“…Naphthoquinone (1,4-NQ) and its derivatives (NQs, juglone, plumbagin, 2-methoxy-1,4-NQ, and menadione) have a variety of therapeutic applications, many of…”
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Reaction Mechanisms of H 2 S Oxidation by Naphthoquinones by Olson, Kenneth R, Clear, Kasey J, Takata, Tsuyoshi, Gao, Yan, Ma, Zhilin, Pfaff, Ella, Travlos, Anthony, Luu, Jennifer, Wilson, Katherine, Joseph, Zachary, Kyle, Ian, Kasko, Stephen M, Jones, Jr, Prentiss, Fukuto, Jon, Xian, Ming, Wu, Gang, Straub, Karl D

“…1,4-naphthoquinones (NQs) catalytically oxidize H S to per- and polysufides and sulfoxides, reduce oxygen to superoxide and hydrogen peroxide, and can form…”
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Reaction Mechanisms of H[sub.2]S Oxidation by Naphthoquinones by Olson, Kenneth R, Clear, Kasey J, Takata, Tsuyoshi, Gao, Yan, Ma, Zhilin, Pfaff, Ella, Travlos, Anthony, Luu, Jennifer, Wilson, Katherine, Joseph, Zachary, Kyle, Ian, Kasko, Stephen M, Jones Jr, Prentiss, Fukuto, Jon, Xian, Ming, Wu, Gang, Straub, Karl D

“…1,4-naphthoquinones (NQs) catalytically oxidize H[sub.2]S to per- and polysufides and sulfoxides, reduce oxygen to superoxide and hydrogen peroxide, and can…”
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Coenzyme Q 10 and related quinones oxidize H 2 S to polysulfides and thiosulfate by Olson, Kenneth R, Clear, Kasey J, Derry, Paul J, Gao, Yan, Ma, Zhilin, Wu, Gang, Kent, Thomas A, Straub, Karl D

“…In the canonical pathway for mitochondrial H S oxidation electrons are transferred from sulfide:quinone oxidoreductase (SQR) to complex III via ubiquinone (CoQ…”
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Redox and Nucleophilic Reactions of Naphthoquinones with Small Thiols and Their Effects on Oxidization of H 2 S to Inorganic and Organic Hydropolysulfides and Thiosulfate by Olson, Kenneth R, Clear, Kasey J, Gao, Yan, Ma, Zhilin, Cieplik, Nathaniel M, Fiume, Alyssa R, Gaziano, Dominic J, Kasko, Stephen M, Luu, Jennifer, Pfaff, Ella, Travlos, Anthony, Velander, Cecilia, Wilson, Katherine J, Edwards, Elizabeth D, Straub, Karl D, Wu, Gang

“…Naphthoquinone (1,4-NQ) and its derivatives (NQs, juglone, plumbagin, 2-methoxy-1,4-NQ, and menadione) have a variety of therapeutic applications, many of…”
Get full text

Naphthoquinones Oxidize H 2 S to Polysulfides and Thiosulfate, Implications for Therapeutic Applications by Olson, Kenneth R, Clear, Kasey J, Derry, Paul J, Gao, Yan, Ma, Zhilin, Cieplik, Nathaniel M, Fiume, Alyssa, Gaziano, Dominic J, Kasko, Stephen M, Narloch, Kathleen, Velander, Cecilia L, Nwebube, Ifeyinwa, Pallissery, Collin J, Pfaff, Ella, Villa, Brian P, Kent, Thomas A, Wu, Gang, Straub, Karl D

“…1,4-Napththoquinones (NQs) are clinically relevant therapeutics that affect cell function through production of reactive oxygen species (ROS) and formation of…”
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Molecular probes for biomembrane recognition by Clear, Kasey J

“…The biological membrane is made up of primarily polar lipids and integral membrane proteins. Polar lipids are a broad class of amphiphilic biomolecules that…”
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