Search Results - "Clayton, Amber J"
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A synthetic synaptic organizer protein restores glutamatergic neuronal circuits
Published in Science (American Association for the Advancement of Science) (28-08-2020)“…Neuronal synapses undergo structural and functional changes throughout life, which are essential for nervous system physiology. However, these changes may also…”
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Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins
Published in Neuron (Cambridge, Mass.) (16-08-2017)“…Neuroligin-neurexin (NL-NRX) complexes are fundamental synaptic organizers in the central nervous system. An accurate spatial and temporal control of NL-NRX…”
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A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability
Published in Human molecular genetics (15-10-2017)“…The discovery of genetic variants influencing sleep patterns can shed light on the physiological processes underlying sleep. As part of a large clinical…”
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Improved expression of secreted and membrane-targeted proteins in insect cells
Published in Biotechnology and applied biochemistry (01-07-2010)“…Secretory and membrane‐bound proteins are generally produced in lower amounts in insect cells compared with cytoplasmic and nuclear proteins. There may be many…”
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Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins
Published in Neuron (Cambridge, Mass.) (06-01-2021)Get full text
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Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins
Published in Neuron (Cambridge, Mass.) (27-09-2017)Get full text
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