Search Results - "Clay, William"

Drugging MYCN through an Allosteric Transition in Aurora Kinase A by Gustafson, William Clay, Meyerowitz, Justin Gabriel, Nekritz, Erin A., Chen, Justin, Benes, Cyril, Charron, Elise, Simonds, Erin F., Seeger, Robert, Matthay, Katherine K., Hertz, Nicholas T., Eilers, Martin, Shokat, Kevan M., Weiss, William A.

“…MYC proteins are major drivers of cancer yet are considered undruggable because their DNA binding domains are composed of two extended alpha helices with no…”
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Targeting MYCN in neuroblastoma by BET bromodomain inhibition by Puissant, Alexandre, Frumm, Stacey M, Alexe, Gabriela, Bassil, Christopher F, Qi, Jun, Chanthery, Yvan H, Nekritz, Erin A, Zeid, Rhamy, Gustafson, William Clay, Greninger, Patricia, Garnett, Matthew J, McDermott, Ultan, Benes, Cyril H, Kung, Andrew L, Weiss, William A, Bradner, James E, Stegmaier, Kimberly

“…Bromodomain inhibition comprises a promising therapeutic strategy in cancer, particularly for hematologic malignancies. To date, however, genomic biomarkers to…”
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An alternative approach to nucleic acid memory by Dickinson, George D., Mortuza, Golam Md, Clay, William, Piantanida, Luca, Green, Christopher M., Watson, Chad, Hayden, Eric J., Andersen, Tim, Kuang, Wan, Graugnard, Elton, Zadegan, Reza, Hughes, William L.

“…DNA is a compelling alternative to non-volatile information storage technologies due to its information density, stability, and energy efficiency. Previous…”
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Treatment of Organophosphorus Poisoning with 6‑Alkoxypyridin-3-ol Quinone Methide Precursors: Resurrection of Methylphosphonate-Aged Acetylcholinesterase by Clay, William K., Buck, Anne K., He, Yiran, Hernández Sánchez, Dalyanne N., Ward, Nathan A., Lear, Jeremy M., Nguyen, Kenny Q., Clark, Benjamin H., Sapia, Ryan J., Lalisse, Remy F., Sriraman, Aishwarya, Cadieux, C. Linn, McElroy, Craig A., Callam, Christopher S., Hadad, Christopher M.

“…Organophosphorus (OP) nerve agents inhibit acetylcholinesterase (AChE), creating a cholinergic crisis in which death can occur. The phosphylated serine residue…”
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The future of wildlife damage management by Clay, William H

“…Clay offers his perspective on what the wildlife damage management profession was like when he began his career, what it's like currently, and what he thinks…”
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Evaluation of Available Data Sources to Prioritize Parishes for Arsenic Monitoring and Outreach Related to Private Well Drinking Water by Katner, Adrienne, Lackovic, Michelle, Streva, Kate, Paul, Vanessa, Trachtman, William “Clay”

“…The objective of this assessment was to identify and evaluate data sets for use in the surveillance of arsenic hazards and private well drinking water use in…”
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Rational design of a monomeric and photostable far‐red fluorescent protein for fluorescence imaging in vivo by Yu, Dan, Dong, Zhiqiang, Gustafson, William Clay, Ruiz‐González, Rubén, Signor, Luca, Marzocca, Fanny, Borel, Franck, Klassen, Matthew P., Makhijani, Kalpana, Royant, Antoine, Jan, Yuh‐Nung, Weiss, William A., Guo, Su, Shu, Xiaokun

“…Fluorescent proteins (FPs) are powerful tools for cell and molecular biology. Here based on structural analysis, a blue‐shifted mutant of a recently engineered…”
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Modes of Calreticulin Recruitment to the Major Histocompatibility Complex Class I Assembly Pathway by Del Cid, Natasha, Jeffery, Elise, Rizvi, Syed Monem, Stamper, Ericca, Peters, Larry Robert, Brown, William Clay, Provoda, Chester, Raghavan, Malini

“…Major histocompatibility complex (MHC) class I molecules are ligands for T-cell receptors of CD8⁺ T cells and inhibitory receptors of natural killer cells…”
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Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain by Yang, Chao-Yie, Delproposto, James, Chinnaswamy, Krishnapriya, Brown, William Clay, Wang, Shuying, Stuckey, Jeanne A, Wang, Xinquan

“…Suppression of Tumorigenicity 2 (ST2), a member of the interleukin-1 receptor (IL-1R) family, activates type 2 immune responses to pathogens and tissue damage…”
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Cultural Diversity in Introductory Psychology Textbook Selection: The Case for Historically Black Colleges/Universities (HBCUs) by Whaley, Arthur L., Clay, William A. L., Broussard, Dominique

“…The present study describes a culturally relevant approach to introductory psychology textbook selection for students attending a historically Black…”
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Mechanism of action of species-selective P2X(7) receptor antagonists by Michel, Anton D, Ng, Sin-Wei, Roman, Shilina, Clay, William C, Dean, David K, Walter, Daryl S

“…AZ11645373 and N-{2-methyl-5-[(1R, 5S)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-ylcarbonyl]phenyl}-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide hydrochloride…”
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Transient and Stable Gene Expression in Mammalian Cells Transduced with a Recombinant Baculovirus Vector by Condreay, J. Patrick, Witherspoon, Sam M., Clay, William C., Kost, Thomas A.

“…Recombinant baculoviruses can serve as gene-transfer vehicles for transient expression of recombinant proteins in a wide range of mammalian cell types…”
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Origin of the Monochromatic Photoemission Peak in Diamondoid Monolayers by Clay, William A, Liu, Zhi, Yang, Wanli, Fabbri, Jason D, Dahl, Jeremy E, Carlson, Robert M. K, Sun, Yun, Schreiner, Peter R, Fokin, Andrey A, Tkachenko, Boryslav A, Fokina, Nataliya A, Pianetta, Piero A, Melosh, Nicholas, Shen, Zhi-Xun

“…Recent photoemission experiments have discovered a highly monochromatized secondary electron peak emitted from diamondoid self-assembled monolayers on metal…”
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Mechanism of action of species‐selective P2X 7 receptor antagonists by Michel, Anton D, Ng, Sin‐Wei, Roman, Shilina, Clay, William C, Dean, David K, Walter, Daryl S

“…Background and purpose:  AZ11645373 and N ‐{2‐methyl‐5‐[(1 R , 5 S…”
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Structure and activity of DmmA, a marine haloalkane dehalogenase by Gehret, Jennifer J., Gu, Liangcai, Geders, Todd W., Brown, William Clay, Gerwick, Lena, Gerwick, William H., Sherman, David H., Smith, Janet L.

“…DmmA is a haloalkane dehalogenase (HLD) identified and characterized from the metagenomic DNA of a marine microbial consortium. Dehalogenase activity was…”
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Photocathode device using diamondoid and cesium bromide films by Clay, William A, Maldonado, Juan R, Pianetta, Piero, Dahl, Jeremy EP, Carlson, Robert MK, Schreiner, Peter R, Fokin, Andrey A, Tkachenko, Boryslav A, Melosh, Nicholas A, Shen, Zhi-Xun

“…A photocathode structure is presented that shows promise for use in high brightness electron sources. The structure consists of a metal substrate, a monolayer…”
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Progress towards personalized therapeutics: biologic- and risk-directed therapy for neuroblastoma by Gustafson, William Clay, Matthay, Katherine K

“…Neuroblastoma, a tumor of the developing peripheral sympathetic nervous system, is the most common and deadly extracranial solid tumor of childhood…”
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Detection of a microRNA signal in an in vivo expression set of mRNAs by Liu, Tsunglin, Papagiannakopoulos, Thales, Puskar, Kathy, Qi, Shuping, Santiago, Fernando, Clay, William, Lao, Kaiqin, Lee, Yohan, Nelson, Stanley F, Kornblum, Harley I, Doyle, Frank, Petzold, Linda, Shraiman, Boris, Kosik, Kenneth S

“…microRNAs (miRNAs) are approximately 21 nucleotide non-coding transcripts capable of regulating gene expression. The most widely studied mechanism of…”
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Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α by Moss, Marcia L, Jin, S.-L. Catherine, Milla, Marcos E, Burkhart, William, Carter, H. Luke, Chen, Wen-Ji, Clay, William C, Didsbury, John R, Hassler, Daniel, Hoffman, Christine R, Kost, Thomas A, Lambert, Millard H, Leesnitzer, M. Anthony, McCauley, Philip, McGeehan, Gerard, Mitchell, Justin, Moyer, Mary, Pahel, Gregory, Rocque, Warren, Overton, Laurie K, Schoenen, Frank, Seaton, Theresa, Su, Jui-Lan, Warner, Janet, Willard, Derril, Becherer, J. David

“…Tumour-necrosis factor-alpha (TNF-alpha) is a cytokine that contributes to a variety of inflammatory disease states. The protein exists as a membrane-bound…”
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The art of applying science: creating a convergence of interests among producers, consumers, regulators and scientists by Clay, Jr, William D

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