Search Results - "Clay, Matthew R."
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Rho activation is apically restricted by Arhgap1 in neural crest cells and drives epithelial-to-mesenchymal transition
Published in Development (Cambridge) (01-08-2013)“…Epithelial-to-mesenchymal transitions (EMTs) are crucial for morphogenesis and carcinoma metastasis, yet mechanisms controlling the underlying cell behaviors…”
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A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation
Published in PLoS genetics (01-01-2016)“…Invadopodia are specialized membrane protrusions composed of F-actin, actin regulators, signaling proteins, and a dynamically trafficked invadopodial membrane…”
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Regulation of cell adhesions and motility during initiation of neural crest migration
Published in Current opinion in neurobiology (01-02-2011)“…Accurate neural crest cell (NCC) migration requires tight control of cell adhesions, cytoskeletal dynamics and cell motility. Cadherins and RhoGTPases are…”
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Head and neck cancer stem cells: The side population
Published in The Laryngoscope (01-03-2011)“…Objectives/Hypothesis: The cancer stem cell (CSC) theory concludes that a subpopulation of cancer cells, the cancer stem cells, can self‐renew and are…”
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Rho-kinase and myosin II affect dynamic neural crest cell behaviors during epithelial to mesenchymal transition in vivo
Published in Developmental biology (15-12-2008)“…The induction and migration of neural crest cells (NCCs) are essential to the development of craniofacial structures and the peripheral nervous system. A…”
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Control of neural crest cell behavior and migration: Insights from live imaging
Published in Cell adhesion & migration (01-10-2010)“…Neural crest cells (NCCs) are a remarkable, dynamic group of cells that travel long distances in the embryo to reach their target sites. They are responsible…”
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Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase
Published in Head & neck (01-09-2010)“…Background In accord with the cancer stem cell (CSC) theory, only a small subset of cancer cells are capable of forming tumors. We previously reported that…”
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Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition
Published in Development (Cambridge) (01-06-2014)“…The epithelial-to-mesenchymal transition (EMT) is a complex change in cell phenotype that is important for cell migration, morphogenesis and carcinoma…”
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Basement Membranes in the Worm: A Dynamic Scaffolding that Instructs Cellular Behaviors and Shapes Tissues
Published in Current topics in membranes (2015)“…The nematode worm Caenorhabditis elegans has all the major basement membrane proteins found in vertebrates, usually with a smaller gene family encoding each…”
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Rho activation is apically restricted by Arhgap1 in neural crest cells and drives epithelial-to-mesenchymal transition
Published in Journal of cell science (01-08-2013)Get full text
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A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation: e1005786
Published in PLoS genetics (01-01-2016)“…Invadopodia are specialized membrane protrusions composed of F-actin, actin regulators, signaling proteins, and a dynamically trafficked invadopodial membrane…”
Get full text
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