Search Results - "Clauss, Wolfgang"

Mechanosensitive activation of CFTR by increased cell volume and hydrostatic pressure but not shear stress by Vitzthum, Constanze, Clauss, Wolfgang G., Fronius, Martin

“…The cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl− channel that is essential for electrolyte and fluid homeostasis. Preliminary evidence…”
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Mechano-sensitivity of epithelial sodium channels (ENaCs): laminar shear stress increases ion channel open probability by Althaus, Mike, Bogdan, Roman, Clauss, Wolfgang G, Fronius, Martin

“…Epithelial cells are exposed to a variety of mechanical forces, but little is known about the impact of these forces on epithelial ion channels. Here we show…”
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Mechano-sensitivity of ENaC: may the (shear) force be with you by Fronius, Martin, Clauss, Wolfgang G.

“…The epithelial Na + channel (ENaC) is the rate-limiting step for Na + absorption in various vertebrate epithelia and deeply enmeshed in the control of salt and…”
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Hydrostatic pressure activates ATP‐sensitive K+ channels in lung epithelium by ATP release through pannexin and connexin hemichannels by Richter, Katrin, Kiefer, Kevin P., Grzesik, Benno A., Clauss, Wolfgang G., Fronius, Martin

“…Lungs of air‐breathing vertebrates are constantly exposed to mechanical forces and therefore are suitable for investigation of mechanotransduction processes in…”
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Why Do We have to Move Fluid to be Able to Breathe? by Fronius, Martin, Clauss, Wolfgang G, Althaus, Mike

“…The ability to breathe air represents a fundamental step in vertebrate evolution that was accompanied by several anatomical and physiological adaptations. The…”
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Laminar shear stress modulates the activity of heterologously expressed P2X(4) receptors by Kessler, Sarah, Clauss, Wolfgang G, Fronius, Martin

“…P2X(4) receptors are involved in mechanotransduction processes, but it is unknown whether or not P2X(4) receptors form mechanosensitive ion channels. This…”
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Nicotinic receptors on rat alveolar macrophages dampen ATP-induced increase in cytosolic calcium concentration by Mikulski, Zbigniew, Hartmann, Petra, Jositsch, Gitte, Zasłona, Zbigniew, Lips, Katrin S, Pfeil, Uwe, Kurzen, Hjalmar, Lohmeyer, Jürgen, Clauss, Wolfgang G, Grau, Veronika, Fronius, Martin, Kummer, Wolfgang

“…Nicotinic acetylcholine receptors (nAChR) have been identified on a variety of cells of the immune system and are generally considered to trigger…”
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Luminal acetylcholine does not affect the activity of the CFTR in tracheal epithelia of pigs by Dittrich, Nikolaus P., Kummer, Wolfgang, Clauss, Wolfgang G., Fronius, Martin

“…Fluid homeostasis mediated by the airway epithelium is required for proper lung function, and the CFTR (cystic fibrosis transmembrane conductance regulator)…”
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Nitric oxide inhibits highly selective sodium channels and the Na+/K+-ATPase in H441 cells by Althaus, Mike, Pichl, Alexandra, Clauss, Wolfgang G, Seeger, Werner, Fronius, Martin, Morty, Rory E

“…Nitric oxide (NO) is an important regulator of Na(+) reabsorption by pulmonary epithelial cells and therefore of alveolar fluid clearance. The mechanisms by…”
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Carbon Monoxide Rapidly Impairs Alveolar Fluid Clearance by Inhibiting Epithelial Sodium Channels by Althaus, Mike, Fronius, Martin, Buchackert, Yasmin, Vadasz, Istvan, Clauss, Wolfgang G, Seeger, Werner, Motterlini, Roberto, Morty, Rory E

“…Carbon monoxide (CO) is currently being evaluated as a therapeutic modality in the treatment of patients with acute lung injury and acute respiratory distress…”
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Amiloride-Sensitive Sodium Channels and Pulmonary Edema by Althaus, Mike, Clauss, Wolfgang G., Fronius, Martin

“…The development of pulmonary edema can be considered as a combination of alveolar flooding via increased fluid filtration, impaired alveolar-capillary barrier…”
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Expression and functional characterization of P2X receptors in mouse alveolar macrophages by Kessler, Sarah, Clauss, Wolfgang G., Günther, Andreas, Kummer, Wolfgang, Fronius, Martin

“…Alveolar macrophages (AM) are crucial for pulmonary host defense, and evidence emerges that ATP-gated P2X receptors are involved in inflammatory processes…”
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Evidence for expression and function of angiotensin II receptor type 1 in pulmonary epithelial cells by Ashry, Omaima, Schnecko, Anja, Clauss, Wolfgang G, Fronius, Martin

“…Highlights • Angiotensin II receptor type 1 is expressed in Xenopus lung and H441 cells. • Apical angiotensin II increases transepithelial short circuit…”
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Gasotransmitters: novel regulators of ion channels and transporters by Althaus, Mike, Clauss, Wolfgang G

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Thiol-reactive compounds from garlic inhibit the epithelial sodium channel (ENaC) by Krumm, Patrick, Giraldez, Teresa, de la Rosa, Diego Alvarez, Clauss, Wolfgang G., Fronius, Martin, Althaus, Mike

“…Epithelial Na+ channels (ENaCs) were heterologously expressed in Xenopus oocytes and exposed to garlic extract and its main compounds. Garlic extract and…”
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Differential N termini in epithelial Na+ channel δ-subunit isoforms modulate channel trafficking to the membrane by Wesch, Diana, Althaus, Mike, Miranda, Pablo, Cruz-Muros, Ignacio, Fronius, Martin, González-Hernández, Tomás, Clauss, Wolfgang G, Alvarez de la Rosa, Diego, Giraldez, Teresa

“…The epithelial Na(+) channel (ENaC) is a heteromultimeric ion channel that plays a key role in Na(+) reabsorption across tight epithelia. The canonical ENaC is…”
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Evidence for basolateral Cl- channels as modulators of apical Cl- secretion in pulmonary epithelia of Xenopus laevis by Berger, Jens, Richter, Katrin, Clauss, Wolfgang G, Fronius, Martin

“…Pulmonary epithelia of air-breathing vertebrates are covered by a thin, fluid layer that is essential for immune defense and gas diffusion. The composition of…”
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Effect of luminal acetylcholine on ENaC- and CFTR-activity in porcine airway epithelium by Dittrich, Nikolaus P, Clauss, Wolfgang G, Kummer, Wolfgang, Fronius, Martin

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Basolateral Cl- uptake mechanisms in Xenopus laevis lung epithelium by Berger, Jens, Hardt, Martin, Clauss, Wolfgang G, Fronius, Martin

“…A thin liquid layer covers the lungs of air-breathing vertebrates. Active ion transport processes via the pulmonary epithelial cells regulate the maintenance…”
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Effect of giving birth on the cortisol level in a bonobo groups’ (Pan paniscus) saliva by Behringer, Verena, Clauß, Wolfgang, Hachenburger, Katja, Kuchar, Alexandra, Möstl, Erich, Selzer, Dieter

“…This study documents the cortisol levels in the saliva of a bonobo group, especially that of a bonobo female which had given birth for the first time. During a…”
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