Search Results - "Clauser, Johanna C."
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Hemolysis at low blood flow rates: in-vitro and in-silico evaluation of a centrifugal blood pump
Published in Journal of translational medicine (05-01-2021)“…Treating severe forms of the acute respiratory distress syndrome and cardiac failure, extracorporeal membrane oxygenation (ECMO) has become an established…”
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2
Ghost cells as a two-phase blood analog fluid-high-volume and high-concentration production
Published in Artificial organs (27-08-2024)“…Hemolysis in mechanical circulatory support systems is currently determined quantitatively. To also locally resolve hemolysis, we are developing a fluorescent…”
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3
Refurbishment of Extracorporeal Life Support Oxygenators in the Context of In Vitro Testing
Published in ASAIO journal (1992) (01-10-2023)“…Refurbishing single use extracorporeal membrane oxygenation (ECMO) oxygenators for in vitro research applications is common. However, the refurbishment…”
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4
The porcine abattoir blood model—Evaluation of platelet function for in‐vitro hemocompatibility investigations
Published in Artificial organs (01-05-2022)“…Background The major obstacle of blood‐contacting medical devices is insufficient hemocompatibility, particularly thrombogenicity and platelet activation…”
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5
Validation of a Miniaturized Test Loop for the Assessment of Human Blood Damage by Continuous-Flow Left-Ventricular Assist Devices
Published in Annals of biomedical engineering (01-12-2021)“…Despite improved hemocompatibility of left-ventricular assist devices (LVADs), assessment of blood damage remains mandatory in preclinical testing as…”
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6
Quantitative analysis of heme and hemoglobin for the detection of intravascular hemolysis
Published in Analytica chimica acta (11-07-2024)“…Intravascular hemolysis is associated with massive release of hemoglobin and consequently labile heme into the blood, resulting in prothrombotic and…”
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Miniaturized Test Loop for the Assessment of Blood Damage by Continuous-Flow Left-Ventricular Assist Devices
Published in Annals of biomedical engineering (01-02-2020)“…Although the hemocompatibility of left-ventricular assist devices (LVADs) has continuously improved, assessment of hemolysis remains mandatory in pre-clinical…”
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8
In vitro thrombogenicity testing of pulsatile mechanical circulatory support systems: Design and proof‐of‐concept
Published in Artificial organs (01-12-2021)“…Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess…”
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Comparison of Aspiration Catheters with Modified Standard Catheters for Treatment of Large Pulmonary Embolism Using an In-vitro Patho-Physiological Model
Published in Cardiovascular and interventional radiology (01-01-2022)“…Purpose The presented in-vitro study provides a comparison of various catheters for mechanical treatment of large-burden pulmonary embolism (PE) under…”
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Hemocompatibility Evaluation of BiomaterialsThe Crucial Impact of Analyzed Area
Published in ACS biomaterials science & engineering (08-02-2021)“…The hemocompatibility of blood-contacting medical devices remains one of the major challenges in medical device development. A common tool for the analysis of…”
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In vitro study on the hemocompatibility of plasma electrolytic oxidation coatings on titanium substrates
Published in Artificial organs (01-04-2020)“…Passively levitated ventricular assist devices (VADs) are vulnerable to impeller‐housing contact and could benefit from surface coatings that improve wear…”
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12
Ghost Cells for Mechanical Circulatory Support In Vitro Testing: A Novel Large Volume Production
Published in Biotechnology journal (01-04-2020)“…The aim of this work is to establish a large volume batch production system to produce sufficient volumes of ghost cells to facilitate hemolysis testing of…”
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Automation of hemocompatibility analysis using image segmentation and supervised classification
Published in Engineering applications of artificial intelligence (01-01-2021)“…The hemocompatibility of blood-contacting medical devices remains one of the major challenges in biomedical engineering and makes research in the field of new…”
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14
Automation of Hemocompatibility Analysis Using Image Segmentation and a Random Forest
Published 13-10-2020“…The hemocompatibility of blood-contacting medical devices remains one of the major challenges in biomedical engineering and makes research in the field of new…”
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