Search Results - "Clauser, Johanna C."

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  1. 1

    Hemolysis at low blood flow rates: in-vitro and in-silico evaluation of a centrifugal blood pump by Schöps, Malte, Groß-Hardt, Sascha H, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Brodie, Daniel, Clauser, Johanna C, Karagiannidis, Christian

    Published in Journal of translational medicine (05-01-2021)
    “…Treating severe forms of the acute respiratory distress syndrome and cardiac failure, extracorporeal membrane oxygenation (ECMO) has become an established…”
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    Journal Article
  2. 2

    Ghost cells as a two-phase blood analog fluid-high-volume and high-concentration production by Schürmann, Benjamin J, Creutz, Pia, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Clauser, Johanna C

    Published in Artificial organs (27-08-2024)
    “…Hemolysis in mechanical circulatory support systems is currently determined quantitatively. To also locally resolve hemolysis, we are developing a fluorescent…”
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    Journal Article
  3. 3

    Refurbishment of Extracorporeal Life Support Oxygenators in the Context of In Vitro Testing by Strudthoff, Lasse J., Hesselmann, Felix, Clauser, Johanna C., Arens, Jutta

    Published in ASAIO journal (1992) (01-10-2023)
    “…Refurbishing single use extracorporeal membrane oxygenation (ECMO) oxygenators for in vitro research applications is common. However, the refurbishment…”
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    Journal Article
  4. 4

    The porcine abattoir blood model—Evaluation of platelet function for in‐vitro hemocompatibility investigations by Clauser, Johanna C., Maas, Judith, Mager, Ilona, Halfwerk, Frank R., Arens, Jutta

    Published in Artificial organs (01-05-2022)
    “…Background The major obstacle of blood‐contacting medical devices is insufficient hemocompatibility, particularly thrombogenicity and platelet activation…”
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  5. 5

    Validation of a Miniaturized Test Loop for the Assessment of Human Blood Damage by Continuous-Flow Left-Ventricular Assist Devices by Woelke, Eva, Mager, Ilona, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Clauser, Johanna C.

    Published in Annals of biomedical engineering (01-12-2021)
    “…Despite improved hemocompatibility of left-ventricular assist devices (LVADs), assessment of blood damage remains mandatory in preclinical testing as…”
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  6. 6

    Quantitative analysis of heme and hemoglobin for the detection of intravascular hemolysis by Hopp, Marie-T., Vaidya, Sonali M., Grimmig, Karina M., Strudthoff, Lasse J., Clauser, Johanna C., Yuan, Xiaojing, Singh, Sneha, Müller, Jens, Oldenburg, Johannes, Hamza, Iqbal, Imhof, Diana

    Published in Analytica chimica acta (11-07-2024)
    “…Intravascular hemolysis is associated with massive release of hemoglobin and consequently labile heme into the blood, resulting in prothrombotic and…”
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  7. 7

    Miniaturized Test Loop for the Assessment of Blood Damage by Continuous-Flow Left-Ventricular Assist Devices by Woelke, Eva, Klein, Mario, Mager, Ilona, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Arens, Jutta, Clauser, Johanna C.

    Published in Annals of biomedical engineering (01-02-2020)
    “…Although the hemocompatibility of left-ventricular assist devices (LVADs) has continuously improved, assessment of hemolysis remains mandatory in pre-clinical…”
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    Journal Article
  8. 8

    In vitro thrombogenicity testing of pulsatile mechanical circulatory support systems: Design and proof‐of‐concept by Brockhaus, Moritz K., Behbahani, Mehdi J., Muris, Farina, Jansen, Sebastian V., Schmitz‐Rode, Thomas, Steinseifer, Ulrich, Clauser, Johanna C.

    Published in Artificial organs (01-12-2021)
    “…Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess…”
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  9. 9
  10. 10

    Hemocompatibility Evaluation of BiomaterialsThe Crucial Impact of Analyzed Area by Clauser, Johanna C, Maas, Judith, Arens, Jutta, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Berkels, Benjamin

    Published in ACS biomaterials science & engineering (08-02-2021)
    “…The hemocompatibility of blood-contacting medical devices remains one of the major challenges in medical device development. A common tool for the analysis of…”
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    Journal Article
  11. 11

    In vitro study on the hemocompatibility of plasma electrolytic oxidation coatings on titanium substrates by Klein, Mario, Kuhn, Yasmin, Woelke, Eva, Linde, Torsten, Ptock, Christoph, Kopp, Alexander, Bletek, Thomas, Schmitz‐Rode, Thomas, Steinseifer, Ulrich, Arens, Jutta, Clauser, Johanna C.

    Published in Artificial organs (01-04-2020)
    “…Passively levitated ventricular assist devices (VADs) are vulnerable to impeller‐housing contact and could benefit from surface coatings that improve wear…”
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    Journal Article
  12. 12

    Ghost Cells for Mechanical Circulatory Support In Vitro Testing: A Novel Large Volume Production by Schöps, Malte, Clauser, Johanna C., Menne, Matthias F., Faßbänder, Dennis, Schmitz‐Rode, Thomas, Steinseifer, Ulrich, Arens, Jutta

    Published in Biotechnology journal (01-04-2020)
    “…The aim of this work is to establish a large volume batch production system to produce sufficient volumes of ghost cells to facilitate hemolysis testing of…”
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    Journal Article
  13. 13

    Automation of hemocompatibility analysis using image segmentation and supervised classification by Clauser, Johanna C., Maas, Judith, Arens, Jutta, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Berkels, Benjamin

    “…The hemocompatibility of blood-contacting medical devices remains one of the major challenges in biomedical engineering and makes research in the field of new…”
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  14. 14

    Automation of Hemocompatibility Analysis Using Image Segmentation and a Random Forest by Clauser, Johanna C, Maas, Judith, Arens, Jutta, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Berkels, Benjamin

    Published 13-10-2020
    “…The hemocompatibility of blood-contacting medical devices remains one of the major challenges in biomedical engineering and makes research in the field of new…”
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    Journal Article