Search Results - "Clausen, E"

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity by Croxford, Andrew L., Lanzinger, Margit, Hartmann, Felix J., Schreiner, Bettina, Mair, Florian, Pelczar, Pawel, Clausen, Björn E., Jung, Steffen, Greter, Melanie, Becher, Burkhard

“…Granulocyte-macrophage colony-stimulating factor (GM-CSF) has emerged as a crucial cytokine produced by auto-reactive T helper (Th) cells that initiate tissue…”
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IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively by Sichien, Dorine, Scott, Charlotte L., Martens, Liesbet, Vanderkerken, Matthias, Van Gassen, Sofie, Plantinga, Maud, Joeris, Thorsten, De Prijck, Sofie, Vanhoutte, Leen, Vanheerswynghels, Manon, Van Isterdael, Gert, Toussaint, Wendy, Madeira, Filipe Branco, Vergote, Karl, Agace, William W., Clausen, Björn E., Hammad, Hamida, Dalod, Marc, Saeys, Yvan, Lambrecht, Bart N., Guilliams, Martin

“…Interferon regulatory factor-8 (IRF8) has been proposed to be essential for development of monocytes, plasmacytoid dendritic cells (pDCs) and type 1…”
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Dendritic cells as gatekeepers of tolerance by Waisman, Ari, Lukas, Dominika, Clausen, Björn E., Yogev, Nir

“…Dendritic cells (DC) are unique hematopoietic cells, linking innate and adaptive immune responses. In particular, they are considered as the most potent…”
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Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin by Romani, Nikolaus, Clausen, Björn E, Stoitzner, Patrizia

“…Langerhans cells (LCs) are antigen-presenting dendritic cells (DCs) that reside in epithelia. The best studied example is the LC of the epidermis. By electron…”
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Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses by Clausen, Björn E, Stoitzner, Patrizia

“…Dendritic cells (DC) are a heterogeneous family of professional antigen-presenting cells classically recognized as most potent inducers of adaptive immune…”
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Dynamically important magnetic fields near accreting supermassive black holes by Zamaninasab, M., Clausen-Brown, E., Savolainen, T., Tchekhovskoy, A.

“…A study of 76 radio-loud active galaxies shows that the magnetic field in the bipolar jet that emanates from each galaxy is tightly correlated with the…”
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Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis by Tran, Sophie, Baba, Ines, Poupel, Lucie, Dussaud, Sébastien, Moreau, Martine, Gélineau, Adélaïde, Marcelin, Geneviève, Magréau-Davy, Elissa, Ouhachi, Melissa, Lesnik, Philippe, Boissonnas, Alexandre, Le Goff, Wilfried, Clausen, Björn E., Yvan-Charvet, Laurent, Sennlaub, Florian, Huby, Thierry, Gautier, Emmanuel L.

“…Kupffer cells (KCs) are liver-resident macrophages that self-renew by proliferation in the adult independently from monocytes. However, how they are maintained…”
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Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection by Sparber, Florian, Dolowschiak, Tamas, Mertens, Sarah, Lauener, Laura, Clausen, Björn E, Joller, Nicole, Stoitzner, Patrizia, Tussiwand, Roxane, LeibundGut-Landmann, Salomé

“…The opportunistic fungal pathogen Candida albicans frequently causes diseases such as oropharyngeal candidiasis (OPC) in immunocompromised individuals…”
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Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin by Nagao, Keisuke, Kobayashi, Tetsuro, Moro, Kazuyo, Ohyama, Manabu, Adachi, Takeya, Kitashima, Daniela Y, Ueha, Satoshi, Horiuchi, Keisuke, Tanizaki, Hideaki, Kabashima, Kenji, Kubo, Akiharu, Cho, Young-hun, Clausen, Björn E, Matsushima, Kouji, Suematsu, Makoto, Furtado, Glaucia C, Lira, Sergio A, Farber, Joshua M, Udey, Mark C, Amagai, Masayuki

“…Hair is a skin component that functions as a physical barrier and thermal regulator. Nagao and colleagues show that hair follicles recruit Langerhans cells to…”
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Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A by Idoyaga, Juliana, Lubkin, Ashira, Fiorese, Christopher, Lahoud, Mireille H, Caminschi, Irina, Huang, Yaoxing, Rodriguez, Anthony, Clausen, Björn E, Park, Chae Gyu, Trumpfheller, Christine, Steinman, Ralph M

“…Improved protein-based vaccines should facilitate the goal of effective vaccines against HIV and other pathogens. With respect to T cells, the efficiency of…”
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Classical DC2 subsets and monocyte‐derived DC: Delineating the developmental and functional relationship by Backer, Ronald A., Probst, Hans Christian, Clausen, Björn E.

“…To specifically tailor immune responses to a given pathogenic threat, dendritic cells (DC) are highly heterogeneous and comprise many specialized subtypes,…”
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β-Catenin in dendritic cells exerts opposite functions in cross-priming and maintenance of CD8⁺ T cells through regulation of IL-10 by Fu, Chunmei, Liang, Xinjun, Cui, Weiguo, Ober-Blöbaum, Julia L., Vazzana, Joseph, Shrikant, Protul A., Lee, Kelvin P., Clausen, Björn E., Mellman, Ira, Jiang, Aimin

“…Recent studies have demonstrated that β-catenin in DCs serves as a key mediator in promoting both CD4⁺ and CD8⁺ T-cell tolerance, although how β-catenin exerts…”
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Talin1 sets the stage for dendritic cell activation by Clausen, Björn E

“…In this issue of JEM, Lim et al. (https://doi.org/10.1084/jem.20191810) provide exciting new evidence that talin1 plays an essential role in dendritic cell…”
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Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity by Bennett, Clare L, van Rijn, Erwin, Jung, Steffen, Inaba, Kayo, Steinman, Ralph M, Kapsenberg, Martien L, Clausen, Björn E

“…Langerhans cells (LC) form a unique subset of dendritic cells (DC) in the epidermis but so far their in vivo functions in skin immunity and tolerance could not…”
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Multicolor fate mapping of Langerhans cell homeostasis by Ghigo, Clément, Mondor, Isabelle, Jorquera, Audrey, Nowak, Jonathan, Wienert, Stephan, Zahner, Sonja P, Clausen, Björn E, Luche, Hervé, Malissen, Bernard, Klauschen, Frederick, Bajénoff, Marc

“…Langerhans cells (LCs) constitute a network of immune sentinels in the skin epidermis that is seeded during embryogenesis. Whereas the development of LCs has…”
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Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions by Nagao, Keisuke, Ginhoux, Florent, Leitner, Wolfgang W, Motegi, Sei-Ichiro, Bennett, Clare L, Clausen, Björn E, Merad, Miriam, Udey, Mark C

“…A new langerin⁺ DC subset has recently been identified in murine dermis (langerin⁺ dDC), but the lineage and functional relationships between these cells and…”
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Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice by Hanson, Julien, Gille, Andreas, Zwykiel, Sabrina, Lukasova, Martina, Clausen, Björn E, Ahmed, Kashan, Tunaru, Sorin, Wirth, Angela, Offermanns, Stefan

“…The antidyslipidemic drug nicotinic acid and the antipsoriatic drug monomethyl fumarate induce cutaneous flushing through activation of G protein-coupled…”
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Langerhans cells are negative regulators of the anti-Leishmania response by Kautz-Neu, Kordula, Noordegraaf, Madelon, Dinges, Stephanie, Bennett, Clare L, John, Dominik, Clausen, Björn E, von Stebut, Esther

“…Migratory skin dendritic cells (DCs) are thought to play an important role in priming T cell immune responses against Leishmania major, but DC subtypes…”
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Dual Therapeutic Efficacy of Vinblastine as a Unique Chemotherapeutic Agent Capable of Inducing Dendritic Cell Maturation by TANAKA, Hiroaki, MATSUSHIMA, Hironori, NISHIBU, Akiko, CLAUSEN, Björn E, TAKASHIMA, Akira

“…Our recent unbiased functional screen of 54 chemotherapeutic drugs unveiled striking heterogeneity in their effects on dendritic cells (DC). Most notably,…”
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E-Cadherin is Dispensable to Maintain Langerhans Cells in the Epidermis by Brand, Anna, Diener, Nathalie, Zahner, Sonja P., Tripp, Christoph, Backer, Ronald A., Karram, Khalad, Jiang, Aimin, Mellman, Ira, Stoitzner, Patrizia, Clausen, Björn E.

“…The cell adhesion molecule E-cadherin is a major component of adherens junctions and marks Langerhans cells (LC), the only dendritic cell (DC) population of…”
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