Search Results - "Clausen, Anne Skovsbo"
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64Cu-DOTATATE Positron Emission Tomography (PET) of Borrelia Burgdorferi Infection: In Vivo Imaging of Macrophages in Experimental Model of Lyme Arthritis
Published in Diagnostics (Basel) (06-10-2020)“…Macrophages play a key role in the inflammatory response in Lyme arthritis (LA) and could be a target for diagnosing and monitoring active Borrelia burgdorferi…”
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Targeted imaging of uPAR expression in vivo with cyclic AE105 variants
Published in Scientific reports (11-10-2023)“…A comprehensive literature reports on the correlation between elevated levels of urokinase-type plasminogen activator receptor (uPAR) and the severity of…”
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Development of a 64Cu-labeled CD4+ T cell targeting PET tracer: evaluation of CD4 specificity and its potential use in collagen-induced arthritis
Published in EJNMMI research (16-09-2022)“…Background CD4 + T cells are central inflammatory mediators in the pathogenesis of autoimmune rheumatoid arthritis (RA), as they are one of the dominating cell…”
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3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism
Published in iScience (20-01-2023)“…Lyme neuroborreliosis (LNB), a tick-borne infection caused by spirochetes within the Borrelia burgdorferi sensu lato (s.L.) complex, is among the most…”
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Synthesis and evaluation of hydrogen peroxide sensitive tofacitinib prodrugs
Published in European journal of medicinal chemistry reports (01-04-2022)“…Tofacitinib (CP-690,550), an approved Janus kinase (JAK) inhibitor, has been proven highly efficacious in treating rheumatoid arthritis (RA). Unfortunately,…”
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Development and Preclinical Evaluation of [211At]PSAt-3-Ga: An Inhibitor for Targeted a-Therapy of Prostate Cancer
Published in The Journal of nuclear medicine (1978) (01-04-2024)“…The application of prostate -specific membrane antigen (PSMA)- targeted a -therapy is a promising alternative to b 2 -particle-based treatments. 211 At is…”
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Development and Preclinical Evaluation of [ 211 At]PSAt-3-Ga: An Inhibitor for Targeted α-Therapy of Prostate Cancer
Published in Journal of Nuclear Medicine (01-04-2024)“…The application of prostate-specific membrane antigen (PSMA)-targeted α-therapy is a promising alternative to β -particle-based treatments. At is among the…”
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Corrigendum to ‘quantitative determination of 64Cu-liposome accumulation at inflammatory and infectious sites: Potential for future theranostic system’: [journal of controlled release 327 (2020) 737–746]
Published in Journal of controlled release (10-02-2021)“…Therapeutic interventions for infectious and inflammatory diseases are becoming increasingly challenging in terms of therapeutic resistance and side-effects…”
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Quantitative determination of 64Cu-liposome accumulation at inflammatory and infectious sites: Potential for future theranostic system
Published in Journal of controlled release (10-11-2020)“…Therapeutic interventions for infectious and inflammatory diseases are becoming increasingly challenging in terms of therapeutic resistance and side-effects…”
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