Search Results - "Claus M. Larsen"

Interleukin-1–Receptor Antagonist in Type 2 Diabetes Mellitus by Larsen, Claus M, Faulenbach, Mirjam, Vaag, Allan, Vølund, Aage, Ehses, Jan A, Seifert, Burkhardt, Mandrup-Poulsen, Thomas, Donath, Marc Y

“…The expression of interleukin-1–receptor antagonist is reduced in pancreatic islets in type 2 diabetes, and high glucose concentrations induce interleukin-1β…”
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Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes by Larsen, Claus M, Faulenbach, Mirjam, Vaag, Allan, Ehses, Jan A, Donath, Marc Y, Mandrup-Poulsen, Thomas

“…OBJECTIVE: Interleukin (IL)-1 impairs insulin secretion and induces β-cell apoptosis. Pancreatic β-cell IL-1 expression is increased and interleukin-1 receptor…”
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Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men by Brøns, Charlotte, Jensen, Christine B., Storgaard, Heidi, Hiscock, Natalie J., White, Andrew, Appel, Julie S., Jacobsen, Stine, Nilsson, Emma, Larsen, Claus M., Astrup, Arne, Quistorff, Bjørn, Vaag, Allan

“…A high-fat, high-calorie diet is associated with obesity and type 2 diabetes. However, the relative contribution of metabolic defects to the development of…”
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Bayesian Synthetic Likelihood for Calibration of Stochastic Radio Channel Model by Adeogun, Ramoni, Larsen, Claus M., Sand, Dennis, Bovbjerg, Holger S., Fisker, Peter K., Gjerde, Tor K.

“…This paper presents a novel Bayesian Synthetic Likelihood (BSL) method for calibration of stochastic radio channels without multi path parameter estimation. To…”
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IL-1 receptor antagonism and muscle gene expression in patients with type 2 diabetes by Berchtold, Lukas A, Larsen, Claus M, Vaag, Allan, Faulenbach, Mirjam, Workman, Christopher T, Kruhøffer, Mogens, Donath, Marc, Mandrup-Poulsen, Thomas

“…We have previously reported that systemic blockade of IL-1beta in patients with type 2 diabetes with anakinra (a recombinant human interleukin-1-receptor…”
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Serum Proteome Pool Changes in Type 2 Diabetic Patients Treated with Anakinra by Koefoed, Mette, Larsen, Claus M, Faulenbach, Mirjam V, Vaag, Allan, Ehses, Jan A, Donath, Marc Y, McGuire, James Norton, Pociot, Flemming, Mandrup-Poulsen, Thomas

“…Introduction High glucose concentrations induce the production of IL-1β in human pancreatic beta cells leading to impaired insulin secretion, decreased cell…”
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Ciliary neurotrophic factor potentiates the β-cell inhibitory effect of IL-1β in rat pancreatic islets associated with increased nitric oxide synthesis and increased expression of inducible nitric oxide synthase by WADT, K. A. W, LARSEN, C. M, ANDERSEN, H. U, NIELSEN, K, KARLSEN, A. E, MANDRUP-POULSEN, T

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The growth arrest and DNA damage-inducible gene inhibits proapoptotic Jun N[H.sub.2]-terminal kinase signaling in pancreatic [beta]-cells exposed to interleukin-1[beta] .(Brief Article) by Larsen, Claus M, Franzoso, Guido, Billestrup, Nils, Mandrup-Poulsen, Thomas

“…By the induction of apoptosis in pancreatic [beta]-cells, interleukin (IL)-1[beta] is believed to be an important mediator of the [beta]-cell destruction…”
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The Growth Arrest and DNA Damage-Inducible Gene (gadd45[beta]) Inhibits Proapoptotic Jun NH^sub 2^-Terminal Kinase Signaling in Pancreatic [beta]-Cells Exposed to Interleukin-1[beta] by Larsen, Claus M, Franzoso, Guido, Billestrup, Nils, Mandrup-Poulsen, Thomas

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Interleukin-1β-induced Rat Pancreatic Islet Nitric Oxide Synthesis Requires Both the p38 and Extracellular Signal-regulated Kinase 1/2 Mitogen-activated Protein Kinases by Larsen, Claus M., Wadt, Karin A.W., Juhl, Lone F., Andersen, Henrik U., Karlsen, Allan E., Su, Michael S.-S., Seedorf, Klaus, Shapiro, Leland, Dinarello, Charles A., Mandrup-Poulsen, Thomas

“…Interleukin-1β (IL-1β) is cytotoxic to rat pancreatic β-cells by inhibiting glucose oxidation, causing DNA damage and inducing apoptosis. Nitric oxide (NO) is…”
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Ciliary neurotrophic factor potentiates the (Beta-cell) inhibitory effect of (IL-1Beta) in rat pancreatic islets associated with increased nitric oxide synthesis by Wadt, Karin A W, Larsen, Claus M, Andersen, Henrik U, Nielsen, Karin

“…Proinflammatory cytokines are implicated as effector molecules in the pathogenesis of IDDM. Interleukin-6 (IL-6) alone or in combination with IL-1beta inhibits…”
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Interleukin-1β-induced Rat Pancreatic Islet Nitric Oxide Synthesis Requires Both the p38 and Extracellular Signal-regulated Kinase 1/2 Mitogen-activated Protein Kinases by Claus M. Larsen, Karin A. W. Wadt, Lone F. Juhl, Henrik U. Andersen, Allan E. Karlsen, Michael S.-S. Su, Klaus Seedorf, Leland Shapiro, Charles A. Dinarello, Thomas Mandrup-Poulsen

“…Interleukin-1β (IL-1β) is cytotoxic to rat pancreatic β-cells by inhibiting glucose oxidation, causing DNA damage and inducing apoptosis. Nitric oxide (NO)…”
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DEXAMETHASONE PREVENTS INTERLEUKIN-1β-MEDIATED INHIBITION OF RAT ISLET INSULIN SECRETION WITHOUT DECREASING NITRIC OXIDE PRODUCTION by Mauricio, Dı́dac, Andersen, Henrik U., Larsen, Claus M., Karlsen, Allan E., Mandrup-Poulsen, Thomas, Nerup, Jørn

“…The deleterious effects of interleukin 1 (IL-1) on insulin-producing β-cells are partly mediated by the generation of the free radical nitric oxide (NO). We…”
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Three Cases of ACTH-Producing Pheochromocytoma – Full Hormonal Workup in Patients With an Adrenal Mass May Be Crucial For Correct Management by Andreassen, Mikkel, Toft, Birgitte Grønkær, Feltoft, Claus Larsen, Hitz, Mette Friberg, Rasmussen, Åse Krogh, Feldt-Rasmussen, Ulla

“…Objective: In rare cases, adrenal medullary tumors secrete adrenocorticotropic hormone (ACTH) in addition to catecholamines.Methods: We present 3 cases of…”
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