Search Results - "Claus, T H"

Effect of CL-316,243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rats by Himms-Hagen, J, Cui, J, Danforth, Jr, E, Taatjes, D J, Lang, S S, Waters, B L, Claus, T H

“…The objective was to assess the effect of a new, highly selective beta 3-adrenergic agonist, CL-316,243 (CL) (J. D. Bloom, M. D. Dutia, B. D. Johnson, A…”
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Hepatic gluconeogenesis/glycolysis : regulation and structure/function relationships of substrate cycle enzymes by PILKIS, S. J, CLAUS, T. H

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Hormonal Regulation of Hepatic Gluconeogenesis and Glycolysis by Pilkis, S J, El-Maghrabi, M R, Claus, T H

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Fructose-2,6-bisphosphate in control of hepatic gluconeogenesis. From metabolites to molecular genetics by Pilkis, S J, el-Maghrabi, M R, Claus, T H

“…Fructose-2,6-bisphosphate in control of hepatic gluconeogenesis. From metabolites to molecular genetics. S J Pilkis , M R el-Maghrabi and T H Claus Department…”
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Beta-3 adrenoceptor selectivity of the dioxolane dicarboxylate phenethanolamines by Dolan, J A, Muenkel, H A, Burns, M G, Pellegrino, S M, Fraser, C M, Pietri, F, Strosberg, A D, Largis, E E, Dutia, M D, Bloom, J D

“…The beta-1, beta-2 and beta-3 adrenergic properties of several benzodioxole-containing phenethanolamines were determined in vitro in both functional and…”
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Regulation of rat liver fructose 2,6-bisphosphatase by El-Maghrabi, M R, Claus, T H, Pilkis, J, Fox, E, Pilkis, S J

“…An enzyme activity that catalyzes the hydrolysis of phosphate from the C-2 position of fructose 2,6-bisphosphate has been detected in rat liver cytoplasm. The…”
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Fructose 2,6-bisphosphate. A new activator of phosphofructokinase by Pilkis, S J, El-Maghrabi, M R, Pilkis, J, Claus, T H, Cumming, D A

“…A new activator of rat liver phosphofructokinase was partially purified from rat hepatocyte extracts by DEAE-Sephadex chromatography. The activator, which…”
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Hormonal Stimulation of DNA Synthesis in Primary Cultures of Adult Rat Hepatocytes by Richman, Robert A., Claus, Thomas H., Pilkis, Simon J., Friedman, Daniel L.

“…Adult rat hepatocytes have been previously isolated and maintained in monolayer culture, but attempts to stimulate DNA synthesis have been unsuccessful…”
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Regulation of 6-phosphofructo-2-kinase Activity by Cyclic AMP-Dependent Phosphorylation by El-Maghrabi, M. Raafat, Claus, Thomas H., Pilkis, Jo, Pilkis, Simon J.

“…Addition of glucagon to isolated rat hepatocytes resulted in inhibition of 6-phosphofructo-2-kinase (ATP:D-fructose-6-phosphate 2-phosphotransferase) activity…”
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The action of insulin on hepatic fructose 2,6-bisphosphate metabolism by Pilkis, S J, Chrisman, T D, El-Maghrabi, M R, Colosia, A, Fox, E, Pilkis, J, Claus, T H

“…The inhibition of hepatocyte 6-phosphofructo-1-kinase by glucagon was suppressed by insulin when the enzyme was measured in crude extracts. However, no effect…”
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Hormonal control of cyclic 3':5'-AMP levels and gluconeogenesis in isolated hepatocytes from fed rats by Pilkis, S J, Claus, T H, Johnson, R A, Park, C R

“…Glucagon can stimulate gluconeogenesis from 2 mM lactate nearly 4-fold in isolated liver cells from fed rats; exogenous cyclic adenosine 3':5'-monophosphate…”
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Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent beta-adrenergic agonist virtually specific for beta 3 receptors. A promising antidiabetic and antiobesity agent by Bloom, J D, Dutia, M D, Johnson, B D, Wissner, A, Burns, M G, Largis, E E, Dolan, J A, Claus, T H

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Modulation of the phosphorylation state of rat liver pyruvate kinase by allosteric effectors and insulin by Claus, T H, El-Maghrabi, M R, Pilkis, S J

“…The regulation of pyruvate kinase in isolated hepatocytes from fasted rats was studied where the intracellular level of fructose 1,6-bisphosphate was elevated…”
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Hormonal control of [14C]glucose synthesis from [U-14C]dihydroxyacetone and glycerol in isolated rat hepatocytes by Pilkis, S J, Riou, J P, Claus, T H

“…The hormonal control of [14C]glucose synthesis from [U-14C-A1dihydroxyacetone was studied in hepatocytes from fed and starved rats. In cells from fed rats,…”
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Regulation of the phosphorylation and activity of 6-phosphofructo 1-kinase in isolated hepatocytes by alpha-glycerolphosphate and fructose 2,6-bisphosphate by Claus, T H, Schlumpf, J R, El-Maghrabi, M R, Pilkis, S J

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The sugar phosphate specificity of rat hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by Pilkis, S J, Pilkis, J, el-Maghrabi, M R, Claus, T H

“…The sugar phosphate specificity of the active site of 6-phosphofructo-2-kinase and of the inhibitory site of fructose-2,6-bisphosphatase was investigated. The…”
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Mechanism of Action of Glucagon on Hepatocyte Phosphofructokinase Activity by Claus, Thomas H., Schlumpf, John R., El-Maghrabi, M. Raafat, Pilkis, Jo, Pilkis, Simon J.

“…Addition of glucagon to isolated hepatocytes reduced the activity of 6-phosphofructokinase (ATP:D-fructose-6-phosphate 1-phosphotransferase, EC 2.7.1.11) and…”
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Influence of phosphorylation on the interaction of effectors with rat liver pyruvate kinase by RAAFAT EL-MAGHRABI, M, CLAUS, T. H, MCGRANE, M. M, PILKIS, S. J

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Effect of diabetes, insulin, starvation, and refeeding on the level of rat hepatic fructose 2,6-bisphosphate by Neely, P., El-Maghrabi, M. R., Pilkis, S. J., Claus, T. H.

“…Effect of diabetes, insulin, starvation, and refeeding on the level of rat hepatic fructose 2,6-bisphosphate. P Neely , M R El-Maghrabi , S J Pilkis and T H…”
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Fructose 2,6-bisphosphate: a mediator of hormone action at the fructose 6-phosphate/fructose 1,6-bisphosphate substrate cycle by Pilkis, S J, El-Maghrabi, M R, McGrane, M, Pilkis, J, Fox, E, Claus, T H

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