Search Results - "Clauditz, Till"
-
1
IMP3 overexpression occurs in various important cancer types and is linked to aggressive tumor features: A tissue microarray study on 8,877 human cancers and normal tissues
Published in Oncology reports (01-01-2018)“…IMP3 is an RNA binding protein required for ribosomal RNA processing, which has been suggested to be a prognostic marker in a large variety of human types of…”
Get full text
Journal Article -
2
CELA3B immunostaining is a highly specific marker for acinar cell carcinoma of the pancreas
Published in PloS one (28-06-2023)“…Chymotrypsin-like elastase family member 3B (CELA3B, elastase-3B) is a pancreatic enzyme with digestive function in the intestine. Since RNA analyses of normal…”
Get full text
Journal Article -
3
Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans
Published in Blood (17-09-2020)“…Acute graft-versus-host disease (GVHD) is a life-threatening complication after allogeneic hematopoietic cell transplantation (allo-HCT). Although currently…”
Get full text
Journal Article -
4
Automated Ki‐67 labeling index assessment in prostate cancer using artificial intelligence and multiplex fluorescence immunohistochemistry
Published in The Journal of pathology (01-05-2023)“…The Ki‐67 labeling index (Ki‐67 LI) is a strong prognostic marker in prostate cancer, although its analysis requires cumbersome manual quantification of Ki‐67…”
Get full text
Journal Article -
5
Carboxypeptidase A1 (CPA1) Immunohistochemistry Is Highly Sensitive and Specific for Acinar Cell Carcinoma (ACC) of the Pancreas
Published in The American journal of surgical pathology (01-01-2022)“…Carboxypeptidase A1 (CPA1) is a zinc metalloprotease that is produced in pancreatic acinar cells and plays a role in cleaving C-terminal branched-chain and…”
Get full text
Journal Article -
6
Lipidome Analysis of Oropharyngeal Tumor Tissues Using Nanosecond Infrared Laser (NIRL) Tissue Sampling and Subsequent Mass Spectrometry
Published in International journal of molecular sciences (25-04-2023)“…Ultrashort pulse infrared lasers can simultaneously sample and homogenize biological tissue using desorption by impulsive vibrational excitation (DIVE). With…”
Get full text
Journal Article -
7
Analyzing expression and phosphorylation of the EGF receptor in HNSCC
Published in Scientific reports (19-09-2019)“…Overexpression of the epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas (HNSCC) is considered to cause increased EGFR activity,…”
Get full text
Journal Article -
8
Trophoblast Cell Surface Antigen 2 Expression in Human Tumors: A Tissue Microarray Study on 18,563 Tumors
Published in Pathobiology (Basel) (2022)“…Trophoblast cell surface antigen 2 (TROP2) is the target of sacituzumab govitecan, an antibody-drug conjugate approved for treatment of triple negative breast…”
Get more information
Journal Article -
9
Aberrant expression of the microtubule-associated protein tau is an independent prognostic feature in prostate cancer
Published in BMC cancer (01-03-2019)“…Microtubule-associated protein Tau (MAPT) overexpression has been linked to poor prognosis and decreased response to taxane-based therapies in several cancer…”
Get full text
Journal Article -
10
Prevalence of S-methyl-5'-thioadenosine Phosphorylase (MTAP) Deficiency in Human Cancer: A Tissue Microarray Study on 13,067 Tumors From 149 Different Tumor Types
Published in The American journal of surgical pathology (01-10-2024)“…Loss of S-methyl-5'-thioadenosine phosphorylase (MTAP) expression is a common event in cancer leading to a critical vulnerability of cancer cells towards…”
Get full text
Journal Article -
11
Up-regulation of Biglycan is Associated with Poor Prognosis and PTEN Deletion in Patients with Prostate Cancer
Published in Neoplasia (New York, N.Y.) (01-09-2017)“…Biglycan (BGN), a proteoglycan of the extracellular matrix, is included in mRNA signatures for prostate cancer aggressiveness. To understand the impact of BGN…”
Get full text
Journal Article -
12
Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers
Published in Experimental and molecular pathology (01-06-2022)“…Combined analysis of cytokeratin 7 (CK7) and cytokeratin 20 (CK20) is often used for assessing the origin of metastatic cancer. To evaluate the diagnostic…”
Get full text
Journal Article -
13
KLK7 expression in human tumors: a tissue microarray study on 13,447 tumors
Published in BMC cancer (03-07-2024)“…Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal…”
Get full text
Journal Article -
14
Marked Prognostic Impact of Minimal Lymphatic Tumor Spread in Prostate Cancer
Published in European urology (01-09-2018)“…Nodal metastasis (N1) is a strong prognostic parameter in prostate cancer; however, lymph node evaluation is always incomplete. To study the prognostic value…”
Get full text
Journal Article -
15
Comparison of INSM1 immunostaining with established neuroendocrine markers synaptophysin and chromogranin A in over 14,000 neuroendocrine and non-neuroendocrine tumors
Published in Molecular and cellular endocrinology (01-02-2024)“…INSM1 is a transcription factor protein which is increasingly used as an immunohistochemical marker for neuroendocrine differentiation. To determine the…”
Get full text
Journal Article -
16
TTF-1 is a highly sensitive but not fully specific marker for pulmonary and thyroidal cancer: a tissue microarray study evaluating more than 17,000 tumors from 152 different tumor entities
Published in Virchows Archiv : an international journal of pathology (01-11-2024)“…Thyroid transcription factor 1 (TTF-1) immunohistochemistry (IHC) is routinely used for the distinction of primary pulmonary adenocarcinomas. However, TTF-1…”
Get full text
Journal Article -
17
TRPS1 is a Highly Sensitive Marker for Breast Cancer: A Tissue Microarray Study Evaluating More Than 19,000 Tumors From 152 Different Tumor Entities
Published in The American journal of surgical pathology (01-06-2024)“…Trichorhinophalangeal syndrome 1 (TRPS1) is a nuclear protein highly expressed in breast epithelial cells. TRPS1 immunohistochemistry (IHC) has been suggested…”
Get full text
Journal Article -
18
PAX8 expression in cancerous and non-neoplastic tissue: a tissue microarray study on more than 17,000 tumors from 149 different tumor entities
Published in Virchows Archiv : an international journal of pathology (01-09-2024)“…PAX8 plays a role in development of the thyroid, kidney, and the Wolffian and Mullerian tract. In surgical pathology, PAX8 immunohistochemistry is used to…”
Get full text
Journal Article -
19
FABP1 expression in human tumors: a tissue microarray study on 17,071 tumors
Published in Virchows Archiv : an international journal of pathology (01-12-2022)“… Fatty acid–binding proteins (FABPs) play a pivotal role in the metabolism of fatty acids and are expressed in a tissue-specific manner. FABP1 is most…”
Get full text
Journal Article -
20
Cadherin-16 (CDH16) immunohistochemistry: a useful diagnostic tool for renal cell carcinoma and papillary carcinomas of the thyroid
Published in Scientific reports (09-08-2023)“…Cadherin-16 (CDH16) plays a role in the embryonal development in kidney and thyroid. Downregulation of CDH16 RNA was found in papillary carcinomas of the…”
Get full text
Journal Article