Search Results - "Claudia Regina Bonini-Domingos"
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Interleukin 17F Gene Polymorphism as a Potential Protective Factor in the Immunopathology of Ocular Toxoplasmosis
Published in Parasite immunology (01-05-2024)“…ABSTRACT Ocular toxoplasmosis (OT) is characterised by intraocular inflammation due to Toxoplasma gondii infection. Studies have found that interleukin 17…”
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Potential utility of melatonin as an antioxidant therapy in the management of sickle cell anemia
Published in Journal of pineal research (01-03-2015)“…This study aimed to assess antioxidant effects of melatonin treatment compared to N‐acetylcysteine (NAC) and to their combination in a sickle cell suspension…”
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The relationship between of ACE I/D and the MTHFR C677T polymorphisms in the pathophysiology of type 2 diabetes mellitus in a population of Brazilian obese patients
Published in Archives of Endocrinology and Metabolism (01-02-2018)“…Objectives This study aimed to evaluate the frequencies of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) and methylenetetrahydrofolate…”
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Twenty Years of Neonatal Screening for Sickle Cell Disease in Brazil: The Challenges of a Continental Country with High Genetic Heterogeneity
Published in Journal of inborn errors of metabolism and screening (2021)“…Abstract Sickle cell disease (SCD) is the most common inherited hematological disease worldwide. The benefits of diagnosis and early intervention have led to…”
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Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01-10-2007)“…We present evidence for Plasmodium vivax infection among Duffy blood group-negative inhabitants of Brazil. The P. vivax identification was determined by both…”
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Anti-Toxoplasma gondii antibodies in patients with beta-hemoglobinopathies: the first report in the Americas
Published in BMC research notes (14-06-2017)“…In Brazil, there have been no previous studies of Toxoplasma gondii infection in sickle cell anemia patients and carriers of severe forms of beta-thalassemia…”
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Effects of benzo[a]pyrene on the blood and liver of Physalaemus cuvieri and Leptodactylus fuscus (Anura: Leptodactylidae)
Published in Environmental pollution (1987) (01-06-2018)“…Benzo[a]pyrene (BaP) is a bio-accumulative toxic compound found in the atmosphere, water, and soil that may affect the life cycle of amphibians. In this study,…”
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Prevalence of βS-globin gene haplotypes, α-thalassemia (3.7 kb deletion) and redox status in patients with sickle cell anemia in the state of Paraná, Brazil
Published in Genetics and molecular biology (01-09-2015)“…The aim of this study was to determine the frequency of beta S-globin gene (β S globin) haplotypes and alpha thalassemia with 3.7 kb deletion (−α 3.7kb…”
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Screening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting
Published in Evolutionary Bioinformatics (01-01-2015)“…Fetal hemoglobin (Hb F) is an important genetic modulator of the beta-hemoglobinopathies. The regulation of Hb F levels is influenced by transcription factors…”
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The 844ins68 cystathionine beta-synthase and C677T MTHFR gene polymorphism and the vaso-occlusive event risk in sickle cell disease
Published in Archives of medical science (01-02-2011)“…Sickle cell disease (SCD) is an inflammatory condition with an increase in the adhesion of sickled erythrocytes, and it is a potential cause of vaso-occlusive…”
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O processo de consentimento livre e esclarecido nas pesquisas em doença falciforme
Published in Revista bioética (01-12-2016)“…Resumo Doença falciforme diz respeito a grupo de hemoglobinopatias associadas à presença da hemoglobina S. Sendo majoritária na população negra, e acometendo…”
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Mixed Plasmodium falciparum infections and its clinical implications in four areas of the Brazilian Amazon region
Published in Acta tropica (2008)“…The aim of this study was to assess the prevalence pattern of mixed- Plasmodium falciparum malaria infections in Brazil by molecular diagnosis and to address…”
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Compound heterozygosity for hemoglobin S and D: what do we need to know?
Published in Revista brasileira de hematologia e hemoterapia (01-07-2016)Get full text
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Polymorphism in the IL-1β promoter is associated with IgG antibody response to circumsporozoite protein repeats of Plasmodium vivax
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (06-11-2020)“…Abstract Background It is well established that infection by Plasmodium vivax is a result of host-parasite interactions. In the present study, association with…”
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Molecular screening of Plasmodium sp. asymptomatic carriers among transfusion centers from brazilian amazon region
Published in Revista do Instituto de Medicina Tropical de São Paulo (01-01-2007)“…The transmission of malaria in Brazil is heterogeneous throughout endemic areas and the presence of asymptomatic Plasmodium sp. carriers (APCs) in the…”
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Hemoglobin D-Punjab: origin, distribution and laboratory diagnosis
Published in Revista brasileira de hematologia e hemoterapia (01-03-2015)“…This review discusses hemoglobin D-Punjab, also known as hemoglobin D-Los Angeles, one of the most common hemoglobin variants worldwide. It is derived from a…”
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Oxidative stress in sickle cell disease: An overview of erythrocyte redox metabolism and current antioxidant therapeutic strategies
Published in Free radical biology & medicine (01-12-2013)“…Erythrocytes have an environment of continuous pro-oxidant generation due to the presence of hemoglobin (Hb), which represents an additional and quantitatively…”
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The Cs a and Cs b Red Cell Antigens of the Cost Blood Group Collection Correspond to the HNA-3a and HNA-3b Neutrophil Antigens: Unexpected Twins with Implications for Sickle Cell Anemia
Published in Blood (02-11-2023)“…Recent genome-wide association and murine studies identified the human neutrophil antigen 3a/b polymorphism (HNA-3a/b) in SLC44A2 (rs2288904-G/A) as a risk…”
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P-212 - Influence of hemoglobin S on metabolic homeostasis of human erythrocytes – partial results
Published in Free radical biology & medicine (20-05-2018)“…This is an initial study regarding the influence of redox imbalance of sickle cells on erythrocyte metabolism. Thus, the study is carrying out on ten patients…”
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Frequencies of ABO, MNSs, and Duffy Phenotypes Among Blood Donors and Malaria Patients from Four Brazilian Amazon Areas
Published in Human biology (01-04-2006)“…We compared the serological phenotypic frequencies of ABO, MNSs, and Duffy in 417 blood donors and 309 malaria patients from four Brazilian Amazon areas. Our…”
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