Search Results - "Claudia Regina Bonini-Domingos"

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    Potential utility of melatonin as an antioxidant therapy in the management of sickle cell anemia by da Silva, Danilo Grünig Humberto, Ricci Jr, Octávio, de Almeida, Eduardo Alves, Bonini-Domingos, Claudia Regina

    Published in Journal of pineal research (01-03-2015)
    “…This study aimed to assess antioxidant effects of melatonin treatment compared to N‐acetylcysteine (NAC) and to their combination in a sickle cell suspension…”
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    Journal Article
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    Twenty Years of Neonatal Screening for Sickle Cell Disease in Brazil: The Challenges of a Continental Country with High Genetic Heterogeneity by Santos, Helena Pimentel dos, Domingos, Claudia Regina Bonini, Castro, Simone Martins de

    “…Abstract Sickle cell disease (SCD) is the most common inherited hematological disease worldwide. The benefits of diagnosis and early intervention have led to…”
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    Effects of benzo[a]pyrene on the blood and liver of Physalaemus cuvieri and Leptodactylus fuscus (Anura: Leptodactylidae) by Fanali, Lara Zácari, Franco-Belussi, Lilian, Bonini-Domingos, Cláudia Regina, de Oliveira, Classius

    Published in Environmental pollution (1987) (01-06-2018)
    “…Benzo[a]pyrene (BaP) is a bio-accumulative toxic compound found in the atmosphere, water, and soil that may affect the life cycle of amphibians. In this study,…”
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    Screening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting by De Souza Carrocini, Gisele Cristine, Venancio, Larissa Paola Rodrigues, Bonini-Domingos, Claudia Regina

    Published in Evolutionary Bioinformatics (01-01-2015)
    “…Fetal hemoglobin (Hb F) is an important genetic modulator of the beta-hemoglobinopathies. The regulation of Hb F levels is influenced by transcription factors…”
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    The 844ins68 cystathionine beta-synthase and C677T MTHFR gene polymorphism and the vaso-occlusive event risk in sickle cell disease by Alves Jacob, Maza, da Cunha Bastos, Celso, Regina Bonini-Domingos, Claudia

    Published in Archives of medical science (01-02-2011)
    “…Sickle cell disease (SCD) is an inflammatory condition with an increase in the adhesion of sickled erythrocytes, and it is a potential cause of vaso-occlusive…”
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    O processo de consentimento livre e esclarecido nas pesquisas em doença falciforme by Valêncio, Luis Felipe Siqueira, Domingos, Claudia Regina Bonini

    Published in Revista bioética (01-12-2016)
    “…Resumo Doença falciforme diz respeito a grupo de hemoglobinopatias associadas à presença da hemoglobina S. Sendo majoritária na população negra, e acometendo…”
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    Hemoglobin D-Punjab: origin, distribution and laboratory diagnosis by Torres, Lidiane de Souza, Okumura, Jéssika Viviani, Silva, Danilo Grünig Humberto da, Bonini-Domingos, Claudia Regina

    “…This review discusses hemoglobin D-Punjab, also known as hemoglobin D-Los Angeles, one of the most common hemoglobin variants worldwide. It is derived from a…”
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    Oxidative stress in sickle cell disease: An overview of erythrocyte redox metabolism and current antioxidant therapeutic strategies by Silva, Danilo Grunig Humberto, Belini Junior, Edis, de Almeida, Eduardo Alves, Bonini-Domingos, Claudia Regina

    Published in Free radical biology & medicine (01-12-2013)
    “…Erythrocytes have an environment of continuous pro-oxidant generation due to the presence of hemoglobin (Hb), which represents an additional and quantitatively…”
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    P-212 - Influence of hemoglobin S on metabolic homeostasis of human erythrocytes – partial results by Chaves, Nayara Alves, Humberto da Silva, Danilo Grünig, Domingos, Claudia Regina Bonini

    Published in Free radical biology & medicine (20-05-2018)
    “…This is an initial study regarding the influence of redox imbalance of sickle cells on erythrocyte metabolism. Thus, the study is carrying out on ten patients…”
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