Search Results - "Claudia, Lefeuvre"
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Genomic characterization of metastatic breast cancers
Published in Nature (London) (01-05-2019)“…Metastasis is the main cause of death for patients with breast cancer. Many studies have characterized the genomic landscape of breast cancer during its early…”
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Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER)
Published in The lancet oncology (01-03-2014)“…Summary Background Breast cancer is characterised by genomic alterations. We did a multicentre molecular screening study to identify abnormalities in…”
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A Pragmatic Study Evaluating NEPA Versus Aprepitant for Prevention of Chemotherapy‐Induced Nausea and Vomiting in Patients Receiving Moderately Emetogenic Chemotherapy
Published in The oncologist (Dayton, Ohio) (01-10-2021)“…Background Neurokinin (NK) 1 receptor antagonists (RAs), administered in combination with a 5‐hydroxytryptamine‐3 (5‐HT3) RA and dexamethasone (DEX), have…”
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Development of multiplex digital PCR assays for the detection of PIK3CA mutations in the plasma of metastatic breast cancer patients
Published in Scientific reports (27-08-2021)“…With the approval of new therapies targeting the PI3K pathway, the detection of PIK3CA mutations has become a key factor in treatment management for HR+/HER2−…”
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Adjustment of young women with breast cancer after chemotherapy: A mediation model of emotional competence via emotional distress
Published in Psycho-oncology (Chichester, England) (01-05-2022)“…Objective Emotional competence (EC) is considered a substantial resource in the adjustment of cancer patients, especially via its effect on anxiety and…”
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Plasma‐based analysis of ERBB2 mutational status by multiplex digital PCR in a large series of patients with metastatic breast cancer
Published in Molecular oncology (01-11-2024)“…Erb‐b2 receptor tyrosine kinase 2 (ERBB2)‐activating mutations are therapeutically actionable alterations found in various cancers, including metastatic breast…”
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Brief Hospital Supervision of Exercise and Diet During Adjuvant Breast Cancer Therapy Is Not Enough to Relieve Fatigue: A Multicenter Randomized Controlled Trial
Published in Nutrients (09-10-2020)“…Supervised exercise dietary programs are recommended to relieve cancer-related fatigue and weight increase induced by adjuvant treatment of early breast cancer…”
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Jaw osteonecrosis in patients treated with denosumab 120 mg with regular dental monitoring: 4-year retrospective study
Published in Journal of oral medicine and oral surgery (2021)“…Background: Medication-related osteonecrosis of the jaw (MRONJ) is an expected, but rare adverse effect of denosumab. There are few data denosumab 120 mg…”
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Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer
Published in The New England journal of medicine (19-12-2019)“…When used as maintenance therapy, the PARP inhibitor olaparib provided a significant progression-free survival benefit in women with ovarian cancer who had a…”
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A phase III randomized multicenter trial evaluating cognition in post-menopausal breast cancer patients receiving adjuvant hormonotherapy
Published in Breast cancer research and treatment (01-08-2015)“…Cognitive impairment, especially verbal episodic memory and executive function impairments, has been considered to be a possible adverse effect of aromatase…”
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Clinical, pathological, and comprehensive molecular analysis of the uterine clear cell carcinoma: a retrospective national study from TMRG and GINECO network
Published in Journal of translational medicine (23-06-2023)“…Uterine clear cell carcinomas (CCC) represent less than 5% of uterine cancers. Their biological characteristics and clinical management remain uncertain. A…”
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Feasibility and efficacy of a supervised home-based physical exercise program for metastatic cancer patients receiving oral targeted therapy: study protocol for the phase II/III - UNICANCER SdS 01 QUALIOR trial
Published in BMC cancer (09-10-2020)“…Currently, oral targeted therapies are known to be effective and are frequently used to treat metastatic cancer patients, but fatigue is a frequently reported…”
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Durvalumab compared to maintenance chemotherapy in metastatic breast cancer: the randomized phase II SAFIR02-BREAST IMMUNO trial
Published in Nature medicine (01-02-2021)“…The impact of single-agent antibodies against programmed death-ligand 1 (PD-L1) as maintenance therapy is unknown in patients with metastatic breast cancer…”
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Immunologic and Clinical Effects of Injecting Mature Peptide-Loaded Dendritic Cells by Intralymphatic and Intranodal Routes in Metastatic Melanoma Patients
Published in Clinical cancer research (15-12-2006)“…Purpose: A phase I/II trial was conducted to evaluate clinical and immunologic responses after intralymphatic and intranodal injections of mature dendritic…”
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Biodistribution of radiolabelled human dendritic cells injected by various routes
Published in European journal of nuclear medicine and molecular imaging (01-07-2005)“…The purpose of this study was to investigate the biodistribution of mature dendritic cells (DCs) injected by various routes, during a cell therapy protocol. In…”
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Osteonecrosis of the jaw under palbociclib: A case series description
Published in Journal of oncology pharmacy practice (01-12-2023)“…Introduction Cases of osteonecrosis of the jaw have been reported by dental surgeons to the pharmacovigilance center in Rennes, France, occurring among…”
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Impact of EPclin on adjuvant therapeutic decision making and comparison of EPclin to the PREDICT tool
Published in The International journal of biological markers (01-06-2021)“…Purpose: Genomic signatures, such as EndoPredict®, may help clinicians to decide which adjuvant treatment is the most appropriate. Methods: We propose the…”
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Patients' preferences for subcutaneous trastuzumab versus conventional intravenous infusion for the adjuvant treatment of HER2-positive early breast cancer: final analysis of 488 patients in the international, randomized, two-cohort PrefHer study
Published in Annals of oncology (01-10-2014)“…Patients with HER2-positive early breast cancer (EBC) preferred subcutaneous (s.c.) trastuzumab, delivered via single-use injection device (SID), over the…”
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