Search Results - "Clasen, Liv S."
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The influence of puberty on subcortical brain development
Published in NeuroImage (Orlando, Fla.) (01-03-2014)“…Puberty is characterized by hormonal, physical and psychological transformation. The human brain undergoes significant changes between childhood and adulthood,…”
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Longitudinal four-dimensional mapping of subcortical anatomy in human development
Published in Proceedings of the National Academy of Sciences - PNAS (28-01-2014)“…Growing access to large-scale longitudinal structural neuroimaging data has fundamentally altered our understanding of cortical development en route to human…”
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3
Sex-chromosome dosage effects on gene expression in humans
Published in Proceedings of the National Academy of Sciences - PNAS (10-07-2018)“…A fundamental question in the biology of sex differences has eluded direct study in humans: How does sex-chromosome dosage (SCD) shape genome function? To…”
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4
Normative brain size variation and brain shape diversity in humans
Published in Science (American Association for the Advancement of Science) (15-06-2018)“…Brain size variation over primate evolution and human development is associated with shifts in the proportions of different brain regions. Individual brain…”
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5
Developmental changes in the structure of the social brain in late childhood and adolescence
Published in Social cognitive and affective neuroscience (01-01-2014)“…Social cognition provides humans with the necessary skills to understand and interact with one another. One aspect of social cognition, mentalizing, is…”
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Prenatal growth in humans and postnatal brain maturation into late adolescence
Published in Proceedings of the National Academy of Sciences - PNAS (10-07-2012)“…Prenatal life encompasses a critical phase of human brain development, but neurodevelopmental consequences of normative differences in prenatal growth among…”
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7
The developmental mismatch in structural brain maturation during adolescence
Published in Developmental neuroscience (01-01-2014)“…Regions of the human brain develop at different rates across the first two decades of life, with some maturing before others. It has been hypothesized that a…”
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Aneuploidy effects on human gene expression across three cell types
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-2023)“…Aneuploidy syndromes impact multiple organ systems but understanding of tissue-specific aneuploidy effects remains limited-especially for the comparison…”
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Sexual dimorphism of brain developmental trajectories during childhood and adolescence
Published in NeuroImage (Orlando, Fla.) (15-07-2007)“…Human total brain size is consistently reported to be ∼ 8–10% larger in males, although consensus on regionally specific differences is weak. Here, in the…”
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Youth with Down syndrome display widespread increased functional connectivity during rest
Published in Scientific reports (14-06-2022)“…Studies of resting-state functional connectivity in young people with Down syndrome (DS) have yielded conflicting results. Some studies have found increased…”
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Sex-biased trajectories of amygdalo-hippocampal morphology change over human development
Published in NeuroImage (Orlando, Fla.) (01-01-2020)“…The amygdala and hippocampus are two adjacent allocortical structures implicated in sex-biased and developmentally-emergent psychopathology. However, the…”
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Psychostimulant Treatment and the Developing Cortex in Attention Deficit Hyperactivity Disorder
Published in The American journal of psychiatry (01-01-2009)“…Objective: While there has been considerable concern over possible adverse effects of psychostimulants on brain development, this issue has not been examined…”
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Dynamic Mapping of Human Cortical Development during Childhood through Early Adulthood
Published in Proceedings of the National Academy of Sciences - PNAS (25-05-2004)“…We report the dynamic anatomical sequence of human cortical gray matter development between the age of 4-21 years using quantitative four-dimensional maps and…”
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Distinct cortical correlates of autistic versus antisocial traits in a longitudinal sample of typically developing youth
Published in The Journal of neuroscience (04-04-2012)“…In humans, behaviors associated with autism and antisociality, disorders characterized by distinct social impairments, can be viewed as quantitative traits…”
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Variegation of autism related traits across seven neurogenetic disorders
Published in Translational psychiatry (07-04-2022)“…Gene dosage disorders (GDDs) constitute a major class of genetic risks for psychopathology, but there is considerable debate regarding the extent to which…”
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Deep phenotypic analysis of psychiatric features in genetically defined cohorts: application to XYY syndrome
Published in Journal of neurodevelopmental disorders (20-02-2023)“…Recurrent gene dosage disorders impart substantial risk for psychopathology. Yet, understanding that risk is hampered by complex presentations that challenge…”
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Anatomical coupling among distributed cortical regions in youth varies as a function of individual differences in vocabulary abilities
Published in Human brain mapping (01-05-2014)“…Patient lesion and functional magnetic resonance imaging (fMRI) studies have provided convincing evidence that a distributed brain network subserves word…”
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Author Correction: Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders
Published in Nature communications (17-11-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans
Published in Proceedings of the National Academy of Sciences - PNAS (04-08-2020)“…Humans display reproducible sex differences in cognition and behavior, which may partly reflect intrinsic sex differences in regional brain organization…”
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Deep Screening for X Chromosome Parent-of-Origin Effects on Neurobehavioral and Neuroanatomical Phenotypes in 47,XXY Klinefelter Syndrome
Published in Biological psychiatry global open science (01-11-2024)“…X chromosome parent of origin (POX) has been proposed as a source of phenotypic variation within sex chromosome aneuploidies such as Klinefelter syndrome…”
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