Search Results - "Clarke, William A."

Hydroxychloroquine Blood Levels in Systemic Lupus Erythematosus: Clarifying Dosing Controversies and Improving Adherence by Durcan, Laura, Clarke, William A, Magder, Laurence S, Petri, Michelle

“…Hydroxychloroquine (HCQ) is used for its effect on systemic lupus erythematosus (SLE) disease activity and longterm benefits. This can be limited by adherence…”
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COVID-19 Serology at Population Scale: SARS-CoV-2-Specific Antibody Responses in Saliva by Pisanic, Nora, Randad, Pranay R, Kruczynski, Kate, Manabe, Yukari C, Thomas, David L, Pekosz, Andrew, Klein, Sabra L, Betenbaugh, Michael J, Clarke, William A, Laeyendecker, Oliver, Caturegli, Patrizio P, Larman, H Benjamin, Detrick, Barbara, Fairley, Jessica K, Sherman, Amy C, Rouphael, Nadine, Edupuganti, Srilatha, Granger, Douglas A, Granger, Steve W, Collins, Matthew H, Heaney, Christopher D

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of an ongoing pandemic that has infected over 36 million and killed over 1 million…”
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Therapeutic drug monitoring in oncology: International Association of Therapeutic Drug Monitoring and Clinical Toxicology consensus guidelines for imatinib therapy by Clarke, William A., Chatelut, Etienne, Fotoohi, Alan K., Larson, Richard A., Martin, Jennifer H., Mathijssen, Ron H.J., Salamone, Salvatore J.

“…Although therapeutic drug monitoring (TDM) is an important tool in guiding drug dosing for other areas of medicine including infectious diseases, cardiology,…”
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Heterologous Ad.26.COV2.S versus homologous BNT162b2/mRNA‐1273 as a third dose in solid organ transplant recipients seronegative after two‐dose mRNA vaccination by Chiang, Teresa PY, Alejo, Jennifer L., Mitchell, Jonathan, Kim, Jake D., Abedon, Aura T., Karaba, Andrew H., Thomas, Letitia, Levan, Macey L., Garonzik‐Wang, Jacqueline M., Avery, Robin K., Pekosz, Andrew, Clarke, William A., Warren, Daniel S., Tobian, Aaron A. R., Massie, Allan B., Segev, Dorry L., Werbel, William A.

“…Heterologous vaccination (“mixing platforms”) for the third (D3) dose of SARS‐CoV‐2 vaccine is a potential strategy to improve antibody responses in solid…”
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Cross-sectional estimates revealed high HIV incidence in Botswana rural communities in the era of successful ART scale-up in 2013-2015 by Moyo, Sikhulile, Gaseitsiwe, Simani, Mohammed, Terence, Pretorius Holme, Molly, Wang, Rui, Kotokwe, Kenanao Peggy, Boleo, Corretah, Mupfumi, Lucy, Yankinda, Etienne Kadima, Chakalisa, Unoda, van Widenfelt, Erik, Gaolathe, Tendani, Mmalane, Mompati O, Dryden-Peterson, Scott, Mine, Madisa, Lebelonyane, Refeletswe, Bennett, Kara, Leidner, Jean, Wirth, Kathleen E, Tchetgen Tchetgen, Eric, Powis, Kathleen, Moore, Janet, Clarke, William A, Lockman, Shahin, Makhema, Joseph M, Essex, Max, Novitsky, Vlad

“…Botswana is close to reaching the UNAIDS "90-90-90" HIV testing, antiretroviral treatment (ART), and viral suppression goals. We sought to determine HIV…”
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Characterization of glycation adducts on human serum albumin by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry by Wa, Chunling, Cerny, Ronald L., Clarke, William A., Hage, David S.

“…Non-enzymatic glycation of human serum albumin (HSA) is associated with the long-term complications of diabetes. We examined the structure and location of…”
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SARS-CoV-2 Antibody Prevalence among Industrial Livestock Operation Workers and Nearby Community Residents, North Carolina, 2021 to 2022 by Gigot, Carolyn, Pisanic, Nora, Kruczynski, Kate, Gregory Rivera, Magdielis, Spicer, Kristoffer, Kurowski, Kathleen M, Randad, Pranay, Koehler, Kirsten, Clarke, William A, Holmes, Phyla, Hall, Jr, D J, Hall, Devon J, Heaney, Christopher D

“…Industrial livestock operations (ILOs), particularly processing facilities, emerged as centers of coronavirus disease 2019 (COVID-19) outbreaks in spring 2020…”
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Validation of a lateral flow chromatographic immunoassay for the detection of fentanyl in drug samples by Park, Ju Nyeong, Sherman, Susan G., Sigmund, Victor, Breaud, Autumn, Martin, Kathryn, Clarke, William A.

“…Drug overdose deaths remain the primary cause of unintentional injuries in the United States. We examined the validity of a fentanyl test strip (FTS) in…”
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New Immunoassays in Therapeutic Drug Monitoring: Where is the Journey Heading? by Salamone, Salvatore J., Courtney, Jodi B., Clarke, William A.

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Characterization of drug binding with alpha1-acid glycoprotein in clinical samples using ultrafast affinity extraction by Beeram, Sandya R., Zhang, Chenhua, Suh, Kyungah, Clarke, William A., Hage, David S.

“…•Ultrafast affinity extraction (UAE) was used to directly examine drug binding by alpha1-acid glycoprotein (AGP) in serum.•Binding by representative drugs from…”
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Rigorous justification of the Whitham modulation equations for equations of Whitham type by Clarke, William A., Marangell, Robert, Perkins, Wesley R.

“…We prove that the modulational instability criterion of the formal Whitham modulation theory agrees with the spectral stability of long‐wavelength…”
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Magnetofluidic immuno-PCR for point-of-care COVID-19 serological testing by Zhang, Pengfei, Chen, Liben, Hu, Jiumei, Trick, Alexander Y., Chen, Fan-En, Hsieh, Kuangwen, Zhao, Yang, Coleman, Branch, Kruczynski, Kate, Pisanic, Thomas R., Heaney, Christopher D., Clarke, William A., Wang, Tza-Huei

“…Serological tests play an important role in the fight against Coronavirus Disease 2019 (COVID-19), including monitoring the dynamic immune response after…”
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Integrated care van delivery of evidence‐based services for people who inject drugs: A cluster‐randomized trial by Page, Kathleen R., Weir, Brian W., Zook, Katie, Rosecrans, Amanda, Harris, Robert, Grieb, Suzanne M., Falade‐Nwulia, Oluwaseun, Landry, Miles, Escobar, Wendy, Ramirez, Michael P., Saxton, Ronald E., Clarke, William A., Sherman, Susan G., Lucas, Gregory M.

“…Background and aims People who inject drugs (PWID) are at risk for adverse outcomes across multiple dimensions. While evidence‐based interventions are…”
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Early Development and Durability of SARS-CoV-2 Antibodies Among Solid Organ Transplant Recipients: A Pilot Study by Boyarsky, Brian J., Ou, Michael T., Werbel, William A., Avery, Robin K., Clarke, William A., Tobian, Aaron A.R., Massie, Allan B., Segev, Dorry L., Garonzik Wang, Jacqueline M.

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Neutralizing activity and 3-month durability of tixagevimab and cilgavimab prophylaxis against Omicron sublineages in transplant recipients by Karaba, Andrew H., Kim, Jake D., Chiang, Teresa P-Y., Alejo, Jennifer L., Sitaras, Ioannis, Abedon, Aura T., Eby, Yolanda, Johnston, Trevor Scott, Li, Maggie, Aytenfisu, Tihitina, Hussey, Casey, Jefferis, Alexa, Fortune, Nicole, Abedon, Rivka, Thomas, Letitia, Habtehyimer, Feben, Ruff, Jessica, Warren, Daniel S., Avery, Robin K., Clarke, William A., Pekosz, Andrew, Massie, Allan B., Tobian, Aaron A.R., Segev, Dorry L., Werbel, William A.

“…Neutralizing antibody (nAb) responses are attenuated in solid organ transplant recipients (SOTRs) despite severe acute respiratory syndrome-coronavirus-2…”
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Implementation of a Self-Audit Tool Improves Regulatory Compliance for Point-of-Care Respiratory Virus Testing in the Emergency Department by Rackow, Ashley R, Mumford, Jeanne, Stauffer, Jennifer, Colburn, Tracy, Bledsoe, Lesley, Clarke, William A

“…Point-of-care testing in the emergency department decreases wait times and supports evidence-based patient care. However, hurdles to successful implementation…”
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The HIV Screening Cascade: Current Emergency Department-Based Screening Strategies Leave Many Patients With HIV Undiagnosed by Mohareb, Amir M., Patel, Anuj V., Laeyendecker, Oliver B., Toerper, Matthew F., Signer, Danielle, Clarke, William A., Kelen, Gabor D., Quinn, Thomas C., Haukoos, Jason S., Rothman, Richard E., Hsieh, Yu-Hsiang

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Persistent SARS-CoV-2–specific immune defects in kidney transplant recipients following third mRNA vaccine dose by Werbel, William A., Karaba, Andrew H., Chiang, Teresa Po-Yu, Massie, Allan B., Brown, Diane M., Watson, Natasha, Chahoud, Maggie, Thompson, Elizabeth A., Johnson, Aileen C., Avery, Robin K., Cochran, Willa V., Warren, Daniel, Liang, Tao, Fribourg, Miguel, Huerta, Christopher, Samaha, Hady, Klein, Sabra L., Bettinotti, Maria P., Clarke, William A., Sitaras, Ioannis, Rouphael, Nadine, Cox, Andrea L., Bailey, Justin R., Pekosz, Andrew, Tobian, Aaron A.R., Durand, Christine M., Bridges, Nancy D., Larsen, Christian P., Heeger, Peter S., Segev, Dorry L.

“…Kidney transplant recipients (KTRs) show poorer response to SARS-CoV-2 mRNA vaccination, yet response patterns and mechanistic drivers following third doses…”
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Fentanyl Delays the Platelet Inhibition Effects of Oral Ticagrelor: Full Report of the PACIFY Randomized Clinical Trial by Ibrahim, Khalil, Shah, Rohan, Goli, Rakesh R, Kickler, Thomas S, Clarke, William A, Hasan, Rani K, Blumenthal, Roger S, Thiemann, David R, Resar, Jon R, Schulman, Steven P, McEvoy, John W

“…Morphine delays oral P2Y platelet inhibitor absorption and is associated with adverse outcomes after myocardial infarction. Consequently, many physicians and…”
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Effect of Intravenous Fentanyl on Ticagrelor Absorption and Platelet Inhibition Among Patients Undergoing Percutaneous Coronary Intervention: The PACIFY Randomized Clinical Trial (Platelet Aggregation With Ticagrelor Inhibition and Fentanyl) by McEvoy, John W, Ibrahim, Khalil, Kickler, Thomas S, Clarke, William A, Hasan, Rani K, Czarny, Matthew J, Keramati, Ali R, Goli, Rakesh R, Gratton, Travis P, Brinker, Jeffrey A, Chacko, Matthews, Hwang, Chao-Wei, Johnston, Peter V, Miller, Julie M, Trost, Jeffrey C, Herzog, William R, Blumenthal, Roger S, Thiemann, David R, Resar, Jon R, Schulman, Steven P

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