Search Results - "Clarke, Nicholas M P"

Standardized Diagnostic Criteria for Developmental Dysplasia of the Hip in Early Infancy by Roposch, Andreas, Liu, Liang Q., Hefti, Fritz, Clarke, Nicholas M. P., Wedge, John H.

“…Background Clinicians use various criteria to diagnose developmental dysplasia of the hip (DDH) in early infancy, but the importance of these various criteria…”
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An Explorative Study into the Aetiology of Developmental Dysplasia of the Hip Using Targeted Urine Metabolomics by Rhodes, Amanda M L, Ali, Sehrish, Minnion, Magdalena, Lee, Ling H, Joseph, Brijil M, Ndzo, Judwin, Clarke, Nicholas M P, Feelisch, Martin, Aarvold, Alexander

“…Developmental dysplasia of the hip (DDH) is the most prevalent congenital musculoskeletal disorder, yet its cause remains unknown. Adequate nutrient provision…”
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Acetabuloplasties at Open Reduction Prevent Acetabular Dysplasia in Intentionally Delayed Developmental Dysplasia of the Hip: A Case-control Study by Carsi, M. Belen, Clarke, Nicholas M. P.

“…Background Avascular necrosis (AVN) and residual acetabular dysplasia are the two main complications of developmental dysplasia of the hip (DDH) treatment…”
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Managing bone and joint infection in children by Faust, Saul N, Clark, Julia, Pallett, Ann, Clarke, Nicholas M P

“…There is little high quality evidence on which to base the management of bone and joint infections in children. This pragmatic practice note aims to provide a…”
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Twenty years experience of selective secondary ultrasound screening for congenital dislocation of the hip by Clarke, Nicholas M P, Reading, Isabel C, Corbin, Charles, Taylor, Colm C, Bochmann, Thomas

“…Objectives The authors report the results of a selective ultrasound screening programme for congenital dislocation of the hip (CDH) over a period of 20 years,…”
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Pleiotrophin/Osteoblast‐Stimulating Factor 1: Dissecting Its Diverse Functions in Bone Formation by Tare, Rahul S., Oreffo, Richard O. C., Clarke, Nicholas M. P., Roach, Helmtrud I.

“…OSF‐1, more commonly known as pleiotrophin (PTN) or heparin‐binding growth‐associated molecule (HB‐GAM), belongs to a new family of secreted HB proteins, which…”
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Induction of Human Osteoprogenitor Chemotaxis, Proliferation, Differentiation, and Bone Formation by Osteoblast Stimulating Factor‐1/Pleiotrophin: Osteoconductive Biomimetic Scaffolds for Tissue Engineering by Yang, Xuebin, Tare, Rahul S, Partridge, Kris A, Roach, Helmtrud I, Clarke, Nicholas MP, Howdle, Steven M, Shakesheff, Kevin M, Oreffo, Richard OC

“…The process of bone growth, regeneration, and remodeling is mediated, in part, by the immediate cell‐matrix environment. Osteoblast stimulating factor‐1…”
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Bilateral acromial fractures in a neonate with epileptic encephalopathy by Jacoby, Joseph, Nicholls, Alexander J., Clarke, Nicholas M. P., Fairhurst, Joanna

“…We present a case of a newborn male with seizures who on subsequent radiographs was shown to have bilateral acromial fractures. These are uncommon fractures…”
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What Is the Impact of Center Variability in a Multicenter International Prospective Observational Study on Developmental Dysplasia of the Hip? by Mulpuri, Kishore, Schaeffer, Emily K., Kelley, Simon P., Castañeda, Pablo, Clarke, Nicholas M. P., Herrera-Soto, Jose A., Upasani, Vidyadhar, Narayanan, Unni G., Price, Charles T.

“…Background Little information exists concerning the variability of presentation and differences in treatment methods for developmental dysplasia of the hip…”
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Late Reduction in Congenital Dislocation of the Hip and the Need for Secondary Surgery: Radiologic Predictors and Confounding Variables by Bolland, Benjamin J, Wahed, Abdul, Al-Hallao, Sariyah, Culliford, David J, Clarke, Nicholas M.P

“…BACKGROUNDDespite early recognition and appropriate treatment of congenital dislocation of the hip, there are a number of cases that subsequently require…”
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Differences in childhood adiposity influence upper limb fracture site by Moon, Rebecca J, Lim, Adelynn, Farmer, Megan, Segaran, Avinash, Clarke, Nicholas M.P, Dennison, Elaine M, Harvey, Nicholas C, Cooper, Cyrus, Davies, Justin H

“…Abstract Introduction Although it has been suggested that overweight and obese children have an increased risk of fracture, recent studies in post-menopausal…”
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Epidemiology of Vitamin D Deficiency in Children Presenting to a Pediatric Orthopaedic Service in the UK by Davies, Justin H, Reed, Joseph M, Blake, Elizabeth, MRCPCH, Max Priesemann, Jackson, Alan A, Clarke, Nicholas M.P

“…BACKGROUND:Vitamin D deficiency may increase predisposition to a number of pediatric orthopaedic conditions and the prevalence of vitamin D deficiency is…”
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Acute haematogenous osteomyelitis in children: is there any evidence for how long we should treat? by Weichert, Stefan, Sharland, Mike, Clarke, Nicholas MP, Faust, Saul N

“…PURPOSE OF REVIEWDespite diagnostic and therapeutic advances, acute haematogenous osteomyelitis in children continues to cause significant morbidity and…”
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Sugioka Transtrochanteric Valgus Osteotomy for Hinge Abduction in Children by Kurup, Harish V, Clarke, Nicholas M.P

“…We report our experience of Sugioka transtrochanteric valgus osteotomy (TVO) for hinge abduction in children. The advantages are early union with simple…”
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Association between the abnormal expression of matrix‐degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions by Roach, Helmtrud I., Yamada, Norikazu, Cheung, Kelvin S. C., Tilley, Simon, Clarke, Nicholas M. P., Oreffo, Richard O. C., Kokubun, Shoichi, Bronner, Felix

“…Objective To investigate whether the abnormal expression of matrix metalloproteinases (MMPs) 3, 9, and 13 and ADAMTS‐4 by human osteoarthritic (OA)…”
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Closed Reduction for Developmental Dysplasia of the Hip: Early-term Results From a Prospective, Multicenter Cohort by Sankar, Wudbhav N, Gornitzky, Alex L, Clarke, Nicholas M P, Herrera-Soto, José A, Kelley, Simon P, Matheney, Travis, Mulpuri, Kishore, Schaeffer, Emily K, Upasani, Vidyadhar V, Williams, Nicole, Price, Charles T

“…Closed reduction (CR) is a common treatment for infantile developmental dysplasia of the hip. The purpose of this observational, prospective, multicenter study…”
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Reliability of a New Radiographic Classification for Developmental Dysplasia of the Hip by Narayanan, Unni, Mulpuri, Kishore, Sankar, Wudbhav N, Clarke, Nicholas M.P, Hosalkar, Harish, Price, Charles T

“…BACKGROUND:Existing radiographic classification schemes (eg, Tönnis criteria) for DDH quantify the severity of disease based on the position of the ossific…”
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Even Experts Can Be Fooled: Reliability of Clinical Examination for Diagnosing Hip Dislocations in Newborns by Harper, Philip, Joseph, Brijil M., Clarke, Nicholas M.P., Herrera-Soto, Jose, Sankar, Wudbhav N., Schaeffer, Emily K., Mulpuri, Kishore, Aarvold, Alexander

“…BACKGROUND:The aim of this study was to assess the accuracy of clinical screening examination in newborns with dislocated hips compared with ultrasound scan…”
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Comparison of Ponseti Versus Surgical Treatment in Congenital Talipes Equinovarus by Clarke, Nicholas M.P., ChM, FRCS, FRCS Ed, Uglow, Michael G., MB, FRCS, Valentine, Katy M., BM

“…Abstract In the present study we compared the rate of relapse after conservative Ponseti treatment method with that of a historical cohort who underwent…”
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The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation by Kanczler, Janos M, Ginty, Patrick J, White, Lisa, Clarke, Nicholas M.P, Howdle, Steven M, Shakesheff, Kevin M, Oreffo, Richard O.C

“…Abstract Regenerating bone tissue involves complex, temporal and coordinated signal cascades of which bone morphogenic protein-2 (BMP-2) and vascular…”
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