Search Results - "Clarke, J. S."

Universal quantum logic in hot silicon qubits by Petit, L., Eenink, H. G. J., Russ, M., Lawrie, W. I. L., Hendrickx, N. W., Philips, S. G. J., Clarke, J. S., Vandersypen, L. M. K., Veldhorst, M.

“…Quantum computation requires many qubits that can be coherently controlled and coupled to each other 1 . Qubits that are defined using lithographic techniques…”
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Neutrophil lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer by Chua, W, Charles, K A, Baracos, V E, Clarke, S J

“…Background: Advances in the treatment of metastatic colorectal cancer (mCRC) in the last decade have significantly improved survival; however, simple…”
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Spin Lifetime and Charge Noise in Hot Silicon Quantum Dot Qubits by Petit, L, Boter, J M, Eenink, H G J, Droulers, G, Tagliaferri, M L V, Li, R, Franke, D P, Singh, K J, Clarke, J S, Schouten, R N, Dobrovitski, V V, Vandersypen, L M K, Veldhorst, M

“…We investigate the magnetic field and temperature dependence of the single-electron spin lifetime in silicon quantum dots and find a lifetime of 2.8 ms at a…”
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A derived neutrophil to lymphocyte ratio predicts survival in patients with cancer by Proctor, M J, McMillan, D C, Morrison, D S, Fletcher, C D, Horgan, P G, Clarke, S J

“…Background: The neutrophil lymphocyte ratio (NLR) has prognostic value in patients with a variety of cancers. Many chemotherapeutic trial databases hold…”
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Interfacing spin qubits in quantum dots and donors—hot, dense, and coherent by Vandersypen, L. M. K., Bluhm, H., Clarke, J. S., Dzurak, A. S., Ishihara, R., Morello, A., Reilly, D. J., Schreiber, L. R., Veldhorst, M.

“…Semiconductor spins are one of the few qubit realizations that remain a serious candidate for the implementation of large-scale quantum circuits. Excellent…”
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Tunable Coupling and Isolation of Single Electrons in Silicon Metal-Oxide-Semiconductor Quantum Dots by Eenink, H. G. J, Petit, L, Lawrie, W. I. L, Clarke, J. S, Vandersypen, L. M. K, Veldhorst, M

“…Extremely long coherence times, excellent single-qubit gate fidelities, and two-qubit logic have been demonstrated with silicon metal-oxide-semiconductor spin…”
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Valley Splitting in Silicon from the Interference Pattern of Quantum Oscillations by Lodari, M, Lampert, L, Zietz, O, Pillarisetty, R, Clarke, J S, Scappucci, G

“…We determine the energy splitting of the conduction-band valleys in two-dimensional electrons confined in silicon metal oxide semiconductor Hall-bar…”
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Inflammation and Cancer: Causes and Consequences by Moore, M M, Chua, W, Charles, K A, Clarke, S J

“…The link between chronic inflammation and increased risk of developing some cancers is well established. The molecular mechanisms that underlie this process…”
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Cognitive function and fatigue after diagnosis of colorectal cancer by Vardy, J., Dhillon, H.M., Pond, G.R., Rourke, S.B., Xu, W., Dodd, A., Renton, C., Park, A., Bekele, T., Ringash, J., Zhang, H., Burkes, R., Clarke, S.J., Tannock, I.F.

“…Cognitive impairment and fatigue have been associated with cancer and its treatment. We present baseline data from a large longitudinal study that evaluates…”
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Use of Inflammatory Markers to Guide Cancer Treatment by Clarke, S J, Chua, W, Moore, M, Kao, S, Phan, V, Tan, C, Charles, K, McMillan, D C

“…Patient‐related factors, especially markers of inflammatory response, are prognostic in many common solid cancers. Here we review how such markers, in…”
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Single-centre experience with peptide receptor radionuclide therapy for neuroendocrine tumours (NETs): results using a theranostic molecular imaging-guided approach by Gordon, S., Chan, D. L. H., Bernard, E. J., Eslick, M. E., Willowson, K. P., Roach, P. J., Engel, A. F., Maher, R., Clarke, S. J., Agarwal, V., Yasmin, L., De Silva, M., Mascall, S., Conner, A., Nevell, D., Pavlakis, N., Bailey, D. L.

“…Aim To summarise our centre’s experience managing patients with neuroendocrine tumours (NETs) in the first 5 years after the introduction of peptide receptor…”
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Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response by RIVORY, L. P, SLAVIERO, K. A, CLARKE, S. J

“…Inflammatory disease states (infection, arthritis) are associated with reduced drug oxidation by the cytochrome P450 3A system. Many chemotherapy agents are…”
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Molecular markers of response and toxicity to FOLFOX chemotherapy in metastatic colorectal cancer by Chua, W, Goldstein, D, Lee, C K, Dhillon, H, Michael, M, Mitchell, P, Clarke, S J, Iacopetta, B

“…Background: To investigate three genetic alterations ( TP53 mutation, Kras mutation and microsatellite instability (MSI)) and three polymorphisms (methylene…”
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A quantum dot crossbar with sublinear scaling of interconnects at cryogenic temperature by Bavdaz, P. L., Eenink, H. G. J., van Staveren, J., Lodari, M., Almudever, C. G., Clarke, J. S., Sebasatiano, F., Veldhorst, M., Scappucci, G.

“…We demonstrate a 36 × 36 gate electrode crossbar that supports 648 narrow-channel field effect transistors (FET) for gate-defined quantum dots, with a…”
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Spin fluctuations away from ( π , 0 ) in the superconducting phase of molecular-intercalated FeSe by Taylor, A. E., Sedlmaier, S. J., Cassidy, S. J., Goremychkin, E. A., Ewings, R. A., Perring, T. G., Clarke, S. J., Boothroyd, A. T.

“…Magnetic fluctuations in the molecular-intercalated FeSe superconductor Li sub(x) (ND sub(2)) sub(y)(ND sub(3)) sub(1-y) Fe sub(2) Se sub(2) (T sub(c) = 43 K)…”
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Priority water research questions as determined by UK practitioners and policy makers by Brown, L.E., Mitchell, G., Holden, J., Folkard, A., Wright, N., Beharry-Borg, N., Berry, G., Brierley, B., Chapman, P., Clarke, S.J., Cotton, L., Dobson, M., Dollar, E., Fletcher, M., Foster, J., Hanlon, A., Hildon, S., Hiley, P., Hillis, P., Hoseason, J., Johnston, K., Kay, P., McDonald, A., Parrott, A., Powell, A., Slack, R.J., Sleigh, A., Spray, C., Tapley, K., Underhill, R., Woulds, C.

“…Several recent studies have emphasised the need for a more integrated process in which researchers, policy makers and practitioners interact to identify…”
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Inflammation and Altered Drug Clearance in Cancer: Transcriptional Repression of a Human CYP3A4 Transgene in Tumor-bearing Mice by Robertson, GR, Liddle, C, Clarke, SJ

“…A tumor‐associated inflammatory response has recently been found to contribute to the considerable interindividual variability in cytotoxic drug clearance seen…”
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Long-term outcome of radiological-guided insertion of implanted central venous access port devices (CVAPD) for the delivery of chemotherapy in cancer patients: institutional experience and review of the literature by VARDY, J, ENGELHARDT, K, WAUGH, R, CLARKE, S. J, COX, K, JACQUET, J, MCDADE, A, BOYER, M, BEALE, P, STOCKLER, M, LONERAGAN, R, DENNIEN, B

“…Central venous access port devices (CVAPD) are necessary for delivery of prolonged infusional chemotherapy or in patients with poor peripheral venous access…”
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Disarming the guarded prognosis: predicting survival in newly referred patients with incurable cancer by STOCKLER, M. R, TATTERSALL, M. H. N, BOYER, M. J, CLARKE, S. J, BEALE, P. J, SIMES, R. J

“…People affected by cancer want information about their prognosis but clinicians have trouble estimating and talking about it. We sought to determine the nature…”
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A phase II study of fixed-dose capecitabine and assessment of predictors of toxicity in patients with advanced metastatic colorectal cancer by SHARMA, R, RIVORY, L, BEALE, P, ONG, S, HORVATH, L, CLARKE, S. J

“…The purpose of this study was to evaluate the safety and activity of fixed-dose capecitabine in patients with advanced colorectal cancer and to correlate…”
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