Search Results - "Clarke, Don"

Notch activation is required for downregulation of HoxA3-dependent endothelial cell phenotype during blood formation by Sanghez, Valentina, Luzzi, Anna, Clarke, Don, Kee, Dustin, Beuder, Steven, Rux, Danielle, Osawa, Mitsujiro, Madrenas, Joaquín, Chou, Tsui-Fen, Kyba, Michael, Iacovino, Michelina

“…Hemogenic endothelium (HE) undergoes endothelial-to-hematopoietic transition (EHT) to generate blood, a process that requires progressive down-regulation of…”
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Brain transplantation of genetically corrected Sanfilippo type B neural stem cells induces partial cross-correction of the disease by Pearse, Yewande, Clarke, Don, Kan, Shih-hsin, Le, Steven Q., Sanghez, Valentina, Luzzi, Anna, Pham, Ivy, Nih, Lina R., Cooper, Jonathan D., Dickson, Patricia I., Iacovino, Michelina

“…Sanfilippo syndrome type B (mucopolysaccharidosis type IIIB) is a recessive genetic disorder that severely affects the brain due to a deficiency in the enzyme…”
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Influence of 10 wk of soy consumption on plasma concentrations and excretion of isoflavonoids and on gut microflora metabolism in healthy adults by WISEMAN, Helen, CASEY, Karen, BOWEY, Elizabeth A, DUFFY, Rosanna, DAVIES, Margaret, ROWLAND, Ian R, LLOYD, Antony S, MURRAY, Alistair, THOMPSON, Richard, CLARKE, Don B

“…Little information is currently available on the role of the gut microflora in modulating isoflavone bioavailability or on sex differences in isoflavone…”
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Mass spectral studies towards more reliable measurement of perfluorooctanesulfonic acid and other perfluorinated chemicals (PFCs) in food matrices using liquid chromatography/tandem mass spectrometry by Lloyd, Antony S., Bailey, Victoria A., Hird, Simon J., Routledge, Anne, Clarke, Don B.

“…Liquid chromatography/mass spectrometry (LC/MS) experiments are described, leading to a reliable method for the measurement of perfluorooctanesulfonic acid…”
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Genetically Corrected iPSC-Derived Neural Stem Cell Grafts Deliver Enzyme Replacement to Affect CNS Disease in Sanfilippo B Mice by Clarke, Don, Pearse, Yewande, Kan, Shih-hsin, Le, Steven Q., Sanghez, Valentina, Cooper, Jonathan D., Dickson, Patricia I., Iacovino, Michelina

“…Sanfilippo syndrome type B (mucopolysaccharidosis type IIIB [MPS IIIB]) is a lysosomal storage disorder primarily affecting the brain that is caused by a…”
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Development of a food compositional database for the estimation of dietary intake of phyto-oestrogens in a group of postmenopausal women previously treated for breast cancer and validation with urinary excretion by Clarke, Don B., Lloyd, Antony S., Lawrence, Judy M., Brown, Jonathan E., Storey, Lesley, Raats, Monique, Rainsbury, Richard M., Culliford, D. J., Bailey-Horne, Victoria A., Parry, Barbara M.

“…The scientific literature contains evidence suggesting that women who have been treated for breast cancer may, as a result of their diagnosis, increase their…”
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A Humoral Immune Response Alters the Distribution of Enzyme Replacement Therapy in Murine Mucopolysaccharidosis Type I by Le, Steven Q, Kan, Shih-Hsin, Clarke, Don, Sanghez, Valentina, Egeland, Martin, Vondrak, Kristen N, Doherty, Terence M, Vera, Moin U, Iacovino, Michelina, Cooper, Jonathan D, Sands, Mark S, Dickson, Patricia I

“…Antibodies against recombinant proteins can significantly reduce their effectiveness in unanticipated ways. We evaluated the humoral response of mice with the…”
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Measurement of intact sulfate and glucuronide phytoestrogen conjugates in human urine using isotope dilution liquid chromatography-tandem mass spectrometry with [formula omitted]isoflavone internal standards by Clarke, Don B, Lloyd, Antony S, Botting, Nigel P, Oldfield, Mark F, Needs, Paul W, Wiseman, Helen

“…A method has been developed for the analysis of phytoestrogens and their conjugates in human urine using liquid chromatography electrospray ionization tandem…”
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Isoflavone Aglycon and Glucoconjugate Content of High- and Low-Soy U.K. Foods Used in Nutritional Studies by Wiseman, Helen, Casey, Karen, Clarke, Don B, Barnes, Karen A, Bowey, Elizabeth

“…The isoflavone aglycon and glucoconjugate content of commercially prepared and “home-prepared” high- and low-soy foods selected for use in an on-going…”
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Influence of soya-based infant formula consumption on isoflavone and gut microflora metabolite concentrations in urine and on faecal microflora composition and metabolic activity in infants and children by Hoey, Leane, Rowland, Ian R., Lloyd, Antony S., Clarke, Don B., Wiseman, Helen

“…The urinary excretion of soya isoflavones and gut microflora metabolites was investigated in infants and children who had been fed soya-based infant formulas…”
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Levels of phytoestrogens, inorganic trace-elements, natural toxicants and nitrate in vegetarian duplicate diets by Clarke, Don B, Barnes, Karen A, Castle, Laurence, Rose, Martin, Wilson, Lesley A, Baxter, Malcolm J, Price, Keith R, DuPont, M.Susan

“…Vegetarian duplicate diets were collected in summer (16) and winter (19) and were analysed for the levels of 13 phytoestrogens, nitrate, 12 trace elements, two…”
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Assessment of performance of laboratories in determining acrylamide in crispbread by CLARKE, Don B, KELLY, Janet, WILSON, Lesley A

“…A proficiency testing round was undertaken to assess the performance of laboratories to measure acrylamide in a sample of crispbread. Retail samples of…”
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Photosynthetic light response curves determined with the leaf oxygen electrode: minimisation of errors and significance of the convexity term by Akhkha, Abdellah, Reid, Iain, Clarke, Don D., Dominy, Peter

“…From photosynthetic studies on a range of monocotyledonous (C-3 and C-4) and dicotyledonous (C-3) plants using a leaf oxygen electrode, we conclude the…”
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Repositioning the Early Pathology of Type 1 Diabetes to the Extraislet Vasculature by Costanzo, Anne, Clarke, Don, Holt, Marie, Sharma, Siddhartha, Nagy, Kenna, Tan, Xuqian, Kain, Lisa, Abe, Brian, Luce, Sandrine, Boitard, Christian, Wyseure, Tine, Mosnier, Laurent O, Su, Andrew I, Grimes, Catherine, Finn, M G, Savage, Paul B, Gottschalk, Michael, Pettus, Jeremy, Teyton, Luc

“…Type 1 diabetes (T1D) is a prototypic T cell-mediated autoimmune disease. Because the islets of Langerhans are insulated from blood vessels by a double…”
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Development of a stem cell gene therapy for Sanfilippo syndrome type B by Clarke, Don L, Sanguez, Valentina, Kan, Shih, Lee, Steven, Iacovino, Michelina, Dickson, Patricia

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Infraspecific Variation of Foliage Terpenes of Podocarpus hallii by Clarke, Don B., Weavers, Rex T., Perry, Nigel B.

“…A detailed study of the levels of sesquiterpenoids and diterpenoids in essential oils from 36 specimens of Podocarpus hallii from two populations has revealed…”
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Infraspecific variation of foliage terpenes of Podocarpus hallii by Clarke, D.B, Weavers, R.T, Perry, N.B

“…A detailed study of the levels of sesquiterpenoids and diterpenoids in essential oils from 36 specimens of Podocarpus hallii from two populations has revealed…”
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Reliéva, a Mahonia aquifolium extract for the treatment of adult patients with atopic dermatitis by Donsky, Howard, Clarke, Don

“…This clinical study was conducted to determine the efficacy and safety of Reliéva cream in adult patients with atopic dermatitis (eczema). This was an…”
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Extraction of perfluorinated compounds from food matrices using fluorous solvent partitioning by Bailey, Victoria Adele, Clarke, Don, Routledge, Anne

“…A novel sample extraction and cleanup procedure has been developed to measure PFOS in fat-containing samples. The extraction is based on fluorous liquid–liquid…”
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Neural stem cells provide continuous enzyme replacement therapy and reduce neuropathology in Sanfilippo syndrome type B mice by Pearse, Yewande E.O., Clarke, Don, Shih-hsin, Kan, Le, Steven Q., Sanghez, Valentina, Cooper, Jonathan D., Dickson, Patricia I., Iacovino, Michelina

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